Atenolol-Chlorthalidone

Atenolol-Chlorthalidone is a combination medication used for the treatment of hypertension (high blood pressure).

• Atenolol-Chlorthalidone is available under the following different brand names: Tenoretic

Common side effects of Atenolol-Chlorthalidone include:

• tired feeling,
• dizziness,
• slow heartbeats,
• depression,
• nausea,
• diarrhea, and
• trouble breathing

Serious side effects of Atenolol-Chlorthalidone include:

• hives,
• difficulty breathing,
• swelling of the face, lips, tongue, or throat,
• cold feeling in the hands and feet,
• yellowing of the skin or feet (jaundice),
• headache,
• confusion,
• slurred speech,
• severe weakness,
• vomiting,
• loss of coordination,
• feeling unsteady,
• uneven heart rate,
• extreme thirst,
• increased urination,
• leg discomfort,
• muscle weakness,
• limp feeling,
• dry mouth,
• restless feeling,
• confusion,
• nausea,
• muscle pain,
• fast heart rate,
• lightheadedness,
• fainting, and
• seizure

Rare side effects of Atenolol-Chlorthalidone include:

• none 

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out.

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Adult dosage

Tablet

• 50 mg/25 mg
• 100 mg/25 mg

Hypertension

Adult dosage

• Initial dose: 50 mg atenolol/25 mg chlorthalidone orally every day
• May increase to 100 mg atenolol/25 mg chlorthalidone orally every day if needed

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

• Atenolol-Chlorthalidone has severe interactions with no other drugs.
• Atenolol-Chlorthalidone has serious interactions with at least 31 other drugs.
• Atenolol-Chlorthalidone has moderate interactions with at least 238 other drugs.
• Atenolol-Chlorthalidone has minor interactions with at least 170 other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all your products. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your healthcare professional or doctor for additional medical advice, or if you have health questions or concerns.

Contraindications

• Anuria
• Cardiogenic shock
• Heart block 2°/3°
• Hypersensitivity to either component or sulfonamides
• Overt cardiac failure
• Sinus bradycardia
• Untreated pheochromocytoma

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Atenolol-Chlorthalidone?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Atenolol-Chlorthalidone?”

Cautions

• Surgery/Anesthesia: Chronically administered beta-blockers should not be routinely withdrawn before major surgery; however, the impaired ability of the heart to respond to reflex adrenergic stimuli may augment the risks of general anesthesia and surgical procedures
• Bronchospastic disease
• Cerebrovascular insufficiency
• Correct hypokalemia before initiating therapy
• CHF, beta-blockade carries the potential hazard of further depressing myocardial contractility and precipitating more severe failure
• Use caution in diabetes mellitus, fluid or electrolyte imbalance (hypochloremic alkalosis, hypercalcemia, hyponatremia), moderate or high cholesterol concentrations, history of asthma, hyperuricemia or gout, hypotension, SLE
• Hyperthyroidism/thyrotoxicosis, liver disease
• May aggravate digitalis toxicity
• Peripheral vascular disease
• Renal impairment
• Risk of male sexual dysfunction
• Sensitivity reactions may occur with or without a history of allergy or asthma
• Compromised left ventricular function
• Patients receiving clonidine - discontinue atenolol several days before the withdrawal of clonidine

Pregnancy and Lactation

• Use in LIFE-THREATENING emergencies when no safer drug is available
• Lactation
  • Excreted in breast milk, use caution