Calcium Vitamin D

Calcium/Vitamin D is an over-the-counter medication used as Calcium Supplementation.

• Calcium/Vitamin D is available under the following different brand names: Caltrate 600+D3, Os-Cal Calcium+D3, Os-Cal Extra D3, Os-Cal Ultra, Citracal.

Adult dosage

Caplet

• 315mg/250IU
• 500mg/200IU
• 500mg/600IU

Capsule

• 600mg/100IU
• 600mg/400IU
• 600mg/500IU
• 600mg/1000IU

Tablet

• 250mg/125IU
• 200mg/250IU
• 250mg/200IU
• 315mg/215IU
• 500mg/200IU
• 600mg/200IU
• 600mg/400IU
• 600mg/800IU

Tablet, chewable

• 250mg/400IU
• 500mg/100IU
• 500mg/200IU
• 500mg/600IU
• 600mg/400IU
• 600mg/800IU

Calcium Supplementation

Adult dosage

Daily dietary reference intake

• 19-50 years: 1000mg/600 IU daily
• 51-70 years (males): 1000 mg/600 IU
• 51 years of age or older (female): 1200 mg/600 IU
• 70 years of age or older (males): 1200 mg/800 IU
• Pregnancy/lactating: 1000 mg/600 IU
• Osteoporosis prevention in adults 50 years of age or older: Vitamin D intake may need to be increased to 800-1000 mg

Daily supplement:

• 1-2 tablets/caplets orally twice daily with or without food (food may increase absorption)

Dosage Considerations – Should be Given as Follows: 

• See "Dosages."

Common side effects of Calcium/Vitamin D include:

• constipation
• upset stomach

Serious side effects of Calcium/Vitamin D include:

• hives, 
• difficulty breathing, 
• swelling of the face, lips, tongue, or throat, 
• nausea, 
• vomiting, 
• loss of appetite, 
• unusual weight loss, 
• mental or mood changes, 
• bone or muscle pain, 
• headache, 
• increased thirst or urination, 
• weakness, 
• unusual tiredness, 
• rash, 
• itching, and
• severe dizziness

Rare side effects of Calcium/Vitamin D include:

• none 

This is not a complete list of side effects and other serious side effects or health problems may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

• Calcium/Vitamin D has severe interactions with no other drugs. 
• Calcium/Vitamin D has serious interactions with the following drug:
  • baloxavir marboxil
• Calcium/Vitamin D has moderate interactions with the following drugs:
  • cabotegravir
  • deferiprone
  • delafloxacin
  • omadacycline
  • rifampin
  • rilpivirine
  • sarecycline
  • sodium sulfate/magnesium sulfate/potassium chloride
  • sodium sulfate/potassium sulfate/magnesium sulfate
• Calcium/Vitamin D has minor interactions with no other drugs. 

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this drug, tell your doctor or pharmacist of all the drugs you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

Contraindications

• Calcium carbonate
• Hypersensitivity
• Hypercalciuria
• Renal calculi
• Hypophosphatemia
• Hypercalcemia
• Suspected digoxin toxicity
• Vitamin D
• Hypercalcemia
• Hypervitaminosis D
• Ergocalciferol (oral): GI, liver, or biliary disease associated with malabsorption of vitamin D analogs. 

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Calcium/Vitamin D?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Calcium/Vitamin D?”

Cautions

• Constipation, bloating, and gas may occur
• Achlorhydria, which is common in elderly, may impair calcium absorption; use the citrate salt and administer with food in such patients
• Hypercalcemia and hypercalciuria may occur in hypoparathyroid patients receiving high doses of vitamin D
• Use caution in patients with renal failure; frequent monitoring of serum calcium and phosphorus necessary to prevent hypercalcemia
• Calcium supplements may interfere with absorption of some medications and minerals; use caution
• Use caution administering calcium supplements to patients with a history of kidney stones

Pregnancy and Lactation

• Available data suggests safe use during pregnancy.
• Available data suggests safe use during lactation.