Ceftibuten

Ceftibuten is a prescription medicine used to treat a wide variety of bacterial infections.

• Ceftibuten is available under the following different brand names: Cedax

Common side effects of Ceftibuten include:

• nausea,
• vomiting,
• diarrhea,
• stomach upset, and
• headache

Serious side effects of Ceftibuten include:

• hives,
• difficulty breathing,
• swelling of the face, lips, tongue, or throat,
• dark urine,
• persistent nausea or vomiting,
• yellowing of the eyes or skin (jaundice),
• black stool,
• change in the amount of urine,
• joint pain,
• fever,
• persistent sore throat,
• easy bleeding,
• unusual bruising,
• tiredness,
• fast or pounding heartbeat,
• seizure,
• mood changes,
• confusion,
• president diarrhea,
• abdominal pain or cramping,
• blood or mucus in the stool,
• white patches in the mouth,
• change in vaginal discharge, and
• severe dizziness

Rare side effects of Ceftibuten include:

• none

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out. 

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Adult and pediatric dosage

Capsule

• 400 mg

Oral suspension

• 90 mg/5mL
• 180 mg/5mL

Infections

Adult dosage

• 400 mg orally every day for 10 days

Pediatric dosage

• Aged below 6 months: Safety and efficacy not established
• 6-12 years old or less than 45 kg: 9 mg/kg orally every day; 400 mg/day orally for 10 days maximum  
• Aged above 12 years old or above 45 kg: As in adults

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

• Ceftibuten has severe interactions with no other drugs.
• Ceftibuten has serious interactions with the following drugs:
  • BCG vaccine live
  • cholera vaccine
  • typhoid vaccine live
• Ceftibuten has moderate interactions with the following drugs:
  • bazedoxifene/conjugated estrogens
  • dienogest/estradiol valerate
  • estradiol
  • estropipate
  • ethinylestradiol
  • levonorgestrel oral/ethinylestradiol/ferrous bisglycinate
  • mestranol
  • mycophenolate
  • pivmecillinam
  • probenecid
  • sodium picosulfate/magnesium oxide/anhydrous citric acid
  • temocillin
  • ticarcillin
  • voclosporin
  • warfarin
  • zinc
• Ceftibuten has minor interactions with at least 49 other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all your products. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your healthcare professional or doctor for additional medical advice, or if you have health questions or concerns.

Contraindications

• Documented hypersensitivity

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Ceftibuten?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Ceftibuten?”

Cautions

• Diabetics: oral suspension contains 1 g sucrose/tsp
• Modify dosage in severe renal impairment; prolonged use may result in superinfection; caution in seizure disorder; may cause antibiotic-associated colitis

Pregnancy and Lactation

• May be acceptable during pregnancy
• Lactation
  • Excretion in milk unknown; use with caution