Cetrorelix

Cetrorelix is a prescription medication used to treat the symptoms of infertility. 

• Cetrorelix is available under the following different brand names: Cetrotide

Common side effects of Cetrorelix include:

• Nausea,
• Headache, and
• Redness, bruising, itching, or swelling at the injection site.

Serious side effects of Cetrorelix include:

• Stomach pain,
• Bloating,
• Nausea,
• Vomiting,
• Diarrhoea,
• Rapid weight gain, especially in the face and midsection,
• Little or no urination,
• Pain while breathing,
• Rapid heart rate, and
• Shortness of breath

Rare side effects of Cetrorelix include:

• None 

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out. 

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Adult dosage

Injectable solution

• 0.25 mg
• 3 mg

Infertility Treatment

Adult dosage

• Single-dose regimen: 3 mg subcutaneous when serum estradiol levels show appropriate stimulation response (range days 5-9) usually day 7; if hCG is not administered within 4 days, continue dose at 0.25 mg/day until hCG administered
• Multiple-dose regimen: 0.25 mg subcutaneous morning or evening of stimulation day 5 or morning of stimulation day 6; continue until hCG administered

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

• Cetrorelix has no noted severe interactions with any other drugs.
• Cetrorelix has no noted serious interactions with any other drugs.
• Cetrorelix has no noted moderate interactions with any other drugs.
• Cetrorelix has no noted minor interactions with any other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all your products. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your healthcare professional or doctor for additional medical advice, or if you have health questions or concerns.

Contraindications

• Pregnancy
• Hypersensitivity
• Breastfeeding

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Cetrorelix?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Cetrorelix?”

Cautions

• May cause elevations of hepatic enzymes: ALT, AST, GGT, AP
• Exclude pregnancy before initiating therapy
• Monitor closely for hypersensitivity following the first injection

Pregnancy and Lactation

• Do not use it during pregnancy.
• Lactation
  • Excretion in milk unknown/contraindicated