How Do Diagnostic Antimicrobials Work?

Tuberculin purified protein derivative (PPD) or Mantoux test belongs to the class of diagnostic antimicrobials and is used to identify tuberculosis infection. It helps to minimize the risk of transmission of infection by early detection and treatment.

PPD is a cell-free purified protein fraction obtained from a human strain of Mycobacterium tuberculosis. When the mycobacterium invades the body, the immune system sends antibodies to attack these microbes. After three to eight weeks, these antibodies enter the bloodstream and then circulate for years. When tuberculin PPD is given, these antibodies react to the purified protein fraction and cause a local reaction.

Diagnostic antimicrobials are used to identify tuberculosis infection in people who are at an increased risk of developing active disease.

Some of the side effects of diagnostic antimicrobials include:

• Rash
• Itching
• Bruising
• Pain, redness, or irritation at the site of injection
• Breathing problems

The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

Generic and brand names of diagnostic antimicrobials include:

• Aplisol
• Mantoux
• PPD
• Sclavo PPD solution
• Tuberculin purified protein derivative
• Tubersol