What is DVT (deep vein thrombosis)?

A venous thromboembolism (VTE) is a blood clot in a deep vein. The most common type of VTE is deep vein thrombosis (DVT), which refers to blood clots in the deep veins of the leg, arm, or pelvis. When blood clots form in the deep veins of the legs, thighs, or pelvis, this can cause blood to back up, resulting in swelling and pain.
DVT can be dangerous because if the blood clot breaks off, it can travel to other parts of the body and block blood vessels there. Blood clots can travel from the legs to the lungs causing pulmonary embolism (PE), which can be fatal.
What are the risk factors for developing DVT during pregnancy?
Pregnancy itself is a risk factor for developing deep vein thrombosis (DVT). Pregnant women have venous thromboembolism (VTE) at a rate 4 to 50 times higher than women who are not pregnant. The risk for venous thromboembolism is higher in the postpartum period, right after a woman has given birth, is two to five times greater.
During pregnancy, factors that increase the risk of DVT and venous thromboembolism include:- Varicose veins
- Diabetes
- Multiple gestations (carrying twins or multiples)
- Inflammatory bowel disease (IBD)
- Urinary tract infection (UTI)
- A body mass index (BMI) of 30 or greater
- Over 35 years of age
- Hospitalization for non-delivery reasons (especially those lasting more than 3 days)
What are the risk factors for developing DVT postpartum?
In the postpartum period, particularly within the first 6 weeks after delivery, risk factors for VTE/DVT include:
- Cesarean section, particularly emergency C-sections
- Stillbirth
- High blood pressure (hypertension)
- Eclampsia or preeclampsia
- Postpartum infection
- Obstetric hemorrhage
- Preterm delivery at less than 36 weeks
- Other underlying medical conditions (such as cardiac disease, varicose veins, inflammatory bowel disease)
- A body mass index (BMI) of 25 or greater
- Age over 35 years
- Smoking

SLIDESHOW
A Visual Guide to Deep Vein Thrombosis (DVT) See SlideshowWhat are the symptoms of DVT?
Common symptoms of DVT in the legs include:
What are the treatment and management guidelines for DVT during pregnancy?
Treatment and management guidelines for deep vein thrombosis (DVT) during pregnancy may include:
- Anticoagulation therapy is the treatment for DVT diagnosed during pregnancy.
- Low-molecular-weight heparins (LMWHs) usually are the first-line medications.
- Anticoagulant therapy may need to be continued into the postpartum period when the risk of DVT/VTE increases.
Warfarin (Coumadin, Jantoven) should be avoided during pregnancy because it can harm a developing fetus.
Is DVT dangerous during pregnancy? Can it be fatal?
Complications of deep vein thrombosis (DVT) during pregnancy may include:
https://www.uptodate.com/contents/deep-vein-thrombosis-and-pulmonary-embolism-in-pregnancy-treatment
Malhotra, MD, Atul and Steven E Weinberger, MD. Deep vein thrombosis in pregnancy: Epidemiology, pathogenesis, and diagnosis. 7 January 2017.
https://www.uptodate.com/contents/deep-vein-thrombosis-in-pregnancy-epidemiology-pathogenesis-and-diagnosis?search=DVT%20pregnancy&source=search_result&selectedTitle=3~150&usage_type=default&display_rank=3
Pai, MD, FRCPC, Menaka and James D Douketis, MD, FRCPC, FACP, FCCP. Patient education: Deep vein thrombosis (DVT) (Beyond the Basics). Updated: May 02, 2018.
https://www.uptodate.com/contents/deep-vein-thrombosis-dvt-beyond-the-basics?search=DVT&source=search_result&selectedTitle=3~150&usage_type=default&display_rank=3#H248133985
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