Eprosartan

Eprosartan is a prescription medication indicated for the treatment of hypertension (high blood pressure). It may be used alone or in combination with other antihypertensives such as diuretics and calcium channel blockers.

• Eprosartan is available under the following different brand names: Teveten

Common side effects of Eprosartan include:

• dizziness
• lightheadedness, and
• blurred vision as the body adjusts to the medication
• runny or stuffy nose
• sore throat
• cough
• joint pain
• nausea
• stomach pain
• diarrhea
• headache
• tired feeling

Serious side effects of Eprosartan include:

• swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
• hoarseness
• difficulty breathing or swallowing

Rare side effects of Eprosartan include:

• none 

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, coordination loss, unsteady, very stiff muscles, high fever, profuse sweating, or tremors
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Adult dosage

Tablet

• 400 mg
• 600 mg

Hypertension

Adult and geriatric dosage

• Initial: 600 mg orally once a day, in patients without intravascular volume depletion
• Maintenance: 400-800 mg/day orally once a day OR divided every 12 hours orally (twice daily may improve effect)
• See also combo with hydrochlorothiazide (Teveten HCT)
• Generally, adjust every month; more aggressively in high-risk patients

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, healthcare provider, or pharmacist first.

• Eprosartan has severe interactions with the following drugs:
  • aliskiren
  • sparsentan
• Eprosartan has serious interactions with the following drugs:
  • benazepril
  • captopril
  • enalapril
  • fosinopril
  • lisinopril
  • lithium
  • lofexidine
  • moexipril
  • perindopril
  • potassium phosphates, IV
  • quinapril
  • ramipril
  • trandolapril
• Eprosartan has moderate interactions with at least 123 other drugs
• Eprosartan has minor interactions with the following drugs:
  • agrimony
  • cornsilk
  • entecavir
  • food
  • noni juice
  • octacosanol
  • patiromer
  • reishi
  • shepherd's purse

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all the products you use. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your healthcare professional or doctor for additional medical advice, health questions, or concerns.

Contraindications

• Hypersensitivity
• Pregnancy (2nd/3rd trimesters): significant risk of fetal/neonatal morbidity and mortality
• Bilateral renal artery stenosis
• Do not coadminister aliskiren in patients with diabetes

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Eprosartan?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Eprosartan?”

Cautions

• Angioedema, hypovolemia, hyperkalemia, surgery, and anesthesia
• Discontinue STAT if pregnant: potential risk for congenital malformations
• Risk for hypotension, especially if hypovolemic/hyponatremic or on concomitant diuretics or dialysis
• Dual blockade of the renin-angiotensin system with angiotensin receptor blockers, angiotensin-converting enzyme inhibitors, or aliskiren associated with an increased risk for hypotension, hyperkalemia, and renal function changes (including acute renal failure) compared with monotherapy
• Risk for anaphylactoid reactions and/or angioedema
• Increased risk for renal dysfunction with congestive heart failure
• Renal/hepatic impairment

Pregnancy and Lactation

• Use with caution if the benefits outweigh the risks during 1st trimester; Use in LIFE-THREATENING emergencies when no safer drug available during 2nd & 3rd trimesters. During the second and third trimesters of pregnancy, these drugs have been associated with fetal injury that includes hypotension, neonatal skull hypoplasia, anuria, reversible or irreversible renal failure, and death
• Lactation 
  • Excretion in milk unknown/not recommended