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EstroGel Drug and Medication User Reviews on RxList

EstroGel

USER REVIEWS

Comment from: Geneviève 55-64 Transgender 1 to 6 months Caregiver Published: July 18

Hi... I am a Transgender Woman just starting medical transition. Have been using EstroGel for 3 months in conjuction with Spironolactone. Even though I've only been taking EstroGel for a short time, I gave it a 5 in 'effectiveness' as my physical changes are on par to what they are supposed to be. Have noted some side effects... anxiety attacks, one severe. Intermittent racing heart and nausea. A one time numbness in my left hand. Anxious to see the full effects of these meds... PS... a note to the Webmaster... Male/Female is one's Sex, Woman/Man is one's Gender...

Comment from: Estrogel 45-54 Transgender 1 to 6 months Caregiver Published: October 18

I’ve been using Estrogel now for just over a month and I have noticed changes. I use two pumps. I started putting it on the outer arm and in the inner thighs I do this in the morning I find I have more energy, maybe a little bit of stomach pain, but nothing major definitely tenderness in my nipples but it’s been two days now and that symptom has gone… no more soreness in my breast. I find I have more energy, and sleep through the night. I think it’s just a matter of being patient and letting it take its course. I react to everything, a very sensitive stomach so far I'm a happy patient. Everyone is different, I truly am happy so far.

Comment from: Beebop 45-54 Transgender 1 to 6 months Caregiver Published: June 29

This estrogen gel is amazing.im 50 years old with endometriosis and I'm postmenopause..I've been using this for 36 days,just one pump a night on my arm..my insomnia is gone ,I sleep so good ,my mood focus brain fog all under control,my sex drive coming back and no more vaginal dryness,no heightened allergies and my dry skin has cleared up..I love it ,10 stars ..

Comment from: RM 55-64 Transgender 6 months to less than 1 year Caregiver Published: June 14

Hysteracomy at 36, at the age of 55, I have been prescribed ESTROGEL since 09/2023, two pumps a day, I was told to start slow and gradually increase. After use for a month, I had tender breasts and painful nipples, and I started having severe headaches and loss of hair. It did not help with hot flashes, I used it for many months, When I stopped the headaches (migraine) stopped.

Comment from: Arlene 55-64 Transgender less than 1 month Caregiver Published: April 15

Been on Estrogel for 3 weeks, game changer. Using this for menopause related insomnia, which affected my quality of life. I can sleep through a night now without sleeping pills, which I used at least 3 times a week. Quality sleep now means no more brain fog, anxiety, irritability. Feeling more energetic. Added bonus no more hot flashes and my sex drive is coming back. Absolutely no side effects, using 2 pumps in the morning after showering.

Comment from: L Lewis 65-74 Transgender less than 1 month Caregiver Published: January 07

This gel is an abomination. I think I need to be about 30 stone to have enough thighs to absorb the prescribed dose

Comment from: Mel 55-64 Transgender 2 to less than 5 years Caregiver Published: November 25

I’ve been using two pumps for over a year. The bottle was oval shaped. When the bottle changed to round the problems began. I thought nothing of the bottle change. The product looked and smelt the same, however, the amount was different. After a few months I began to have symptoms again, nightsweats, anxiety, then I started bleeding which is very alarming . I changed to patches for a while which frankly I dislike. I’ve tested the weight pumped out with my jewellers digital scales..it’s all over the place. Not consistent. I’ve reported it to yellow flag as have lots of other ladies..but we are still being prescribed this excellent medicine in INEFFECTIVE PACKAGING. sort it out please!

Comment from: Deborah Transgender 2 to less than 5 years Caregiver Published: November 14

After having a full hysterectomy I was prescribed this gel, at first it worked great but since they’ve changed the packaging it’s awful, there is a forum whereby lots of women have said the same thing. My legs constantly hurt, I’m always extremely hot, agitated, emotional and now have major anxiety amongst other things.

Comment from: Mandy Transgender 1 to 6 months Caregiver Published: November 02

I have been taken off the one a day HRT tablets and out onto the pump, I don’t particularly like the stickiness of the gel but once my hands are washed after rubbing it in, its ok. I appreciate the instructions for use are on a separate leaflet but it’s impossible to read the yellow print on the back of the tube. Perhaps the manufacturers could consider their target market and ensure this print has more contrast to the white background?

Comment from: Fi 45-54 Transgender 1 to 6 months Caregiver Published: October 12

Increased blood pressure and agitation. Don’t like the strong smell of alcohol in the gel, and feel this isn’t a healthy option to increase oestrogen

Comment from: Anne-Marie 55-64 Transgender 1 to 6 months Caregiver Published: May 15

Never had hot flashes or vaginal dryness, just generally feeling very warm all the time. This has been a great help with brain fog, fatigue, muscle aches and motivation in general. A life-changer!

Comment from: Nicola J G 45-54 Transgender less than 1 month Caregiver Published: March 11

Age 51 & in UK. 5th year on HRT...Femostan 1 & 2 both successful. Need for change now as I've just had a full hysterectomy. Started on Oestrogel, 4 pumps daily (inner thighs 2 morning/2 evening) & Utrogestan (a bioidentical progesterone tablet) taken at bed time.(Still need progesterone due to severity of endometriosis). 2 weeks in & all seems very positive...although still recovering from surgery I have no horrid menopause signs so here's hoping!! Good luck ladies :-)

Comment from: Angela Troy 55-64 Transgender 5 to less than 10 years Caregiver Published: March 04

This treatment is hailed as the holy grail of HRT by many gynaecologists. It helps slow down the onset of dementia and osteoporosis as well as reducing the risk of breast cancer. However it MUST be used with a progesterone as used alone it can cause thickening of the lining of the womb which can be very dangerous. Coupled with the mirena coil I have had many years of relief from awful menopausal symptoms. My mood swings, hot flushes and joint aches and pains have all ceased. Even though I am now 58 my gynea has advsied me to continue to use for as long as possible as it really does carry so many health benefits as we get older. As for hair loss, I have not experienced this although it can be a natural ide effect of the menopause for some

Comment from: Rita 65-74 Transgender 1 to 6 months Caregiver Published: November 29

I have been using for about three months....hot flashes gone but so is my hair....falling out in globs since using the gel. That is the only thing I can contribute this too as I did not have a hair in my brush and now I can make a toupe! Don't know what to do .... may half my doses to control hair loss!

Comment from: Janice 45-54 Transgender 10 years or more Caregiver Published: June 11

Marked it excellent as it has been for years, until my last refill & I received one different looking bottle. Pharmacist said same product, new look. But it's definitely not the same. Hot flashes, etc all came back within 2 weeks of using. Still had one of the older design bottles left so went back to that and symptoms disappeared. Something has changed with the product, or I received a bad bottle.

Comment from: Lesley 45-54 Transgender 1 to 6 months Caregiver Published: March 16

I’ve been using oestrogel for 5 weeks now, because have osteoporosis my GP said I had to do something for my bones ass high calcium diet had issues with my heart. Plus side my skins softer better, sleeping better too and vaginal atrophy changed now the tissue down there is engorged. Bad effects nausea, I’ve noticed increased pain in joints/muscles and my abdomen, bloating, fluid retention, honestly I feel strange to say the least … not sure how I feel about it yet with bone health in mind?? I’ll try it for 3 months as my GP asked me to? I had radical hysterectomy in 2011 I stopped HRT because was awful in 2013. I’ve had no oestrogen for 10yrs so I’m not sure if this will help or not?? I find it easy to use and it’s safer than the tablets. Time will tell !

Comment from: 0-2 Transgender 1 to 6 months Caregiver Published: December 28

I apply 2 pumps of estrogel and I’m on promethium (100mg) tablets, and I’ve nearly been on it for 2 months. I love it and it has changed my life. I had server hot flashes day and night everyday and my mood was all over the place. my periods had stopped for 7 months before taking it and now I have regular light periods and no hot flashes at all. Love it!!

Comment from: Dee 45-54 Transgender 1 to 6 months Caregiver Published: November 11

On one pump a day sleeping like a baby but brain fog and agitation very extreme so going to stop. I'm also on evorel patches

Comment from: Helen 55-64 Transgender less than 1 month Caregiver Published: October 25

I experienced pins and needles down my arms to my hands and numb hands at night. Also felt heart racing. Had stopped using

Comment from: Fiona 35-44 Transgender 1 to 6 months Caregiver Published: September 14

Ignore the people saying this is synthetic. This is a bioidentical product made from yams and soy. It also won’t make you gain weight. If your levels of this hormone are too low then you will gain weight. In the U.K. where I am starting dose is 2 pumps which is working well for me with night sweats, moodiness, aching joints and lack of energy all sorted. We can take up to 4 pumps a day here if needed. I’d argue that you aren’t using enough over there. I’m also on bioidentical progesterone at night which helps me sleep. Look up The Menopause Doctor in the U.K. Her website and app give fantastic advice based on real research and science. This medication has changed my life

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What Is Osteoporosis? Treatment, Symptoms, Medication See Slideshow
References
Medical Editor: John P. Cunha, DO, FACOEP