What Is Etripamil intranasal and How Does It Work?
Etripamil is used to restore a normal heart rhythm in adults who have symptoms of sudden episodes of fast heartbeat, also called paroxysmal supraventricular tachycardia (PSVT).
It works by blocking the flow of calcium into certain cells of the heart and blood vessels. By interrupting the abnormal electrical signals in the heart, Etripamil helps your heart return to a normal rhythm.
- Etripamil is available under the following different brand names: Cardamyst.
What Are Side Effects Associated with Using Etripamil intranasal?
Common side effects of Etripamil intranasal include:
- Nasal discomfort
- Runny nose or stuffy nose
- Sore throat
- Nosebleed
Serious side effects of Etripamil include:
- Fainting. Cardamyst may cause effects on blood pressure, heart rate, and the electrical activity of the heart that lead to dizziness or fainting. This is more likely if you have a history of fainting or certain heart problems. You should use this medicine while sitting in a safe area where you are unlikely to fall. If you feel lightheaded, lie down.
This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.
What Are the Dosages of Etripamil intranasal?
Dosage Forms & Strengths
- Nasal Spray: 70 mg per device
Paroxysmal Supraventricular Tachycardia (PSVT)
Adult Dose: One spray in each nostril (70 mg total) as soon as symptoms start. If symptoms continue after 10 minutes, a second dose of one spray in each nostril (70 mg) may be used. Do not use more than 140 mg (2 devices) in a 24-hour period.
Pediatric Dose: Safety and effectiveness have not been established in children.
What Other Drugs Interact with Etripamil intranasal?
Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if Etripamil is right for you.
This may not be a complete list of medicines that can interact with Etripamil. Always check with your health care provider.
What Are Warnings and Precautions for Etripamil intranasal?
Contraindications
Do not use Etripamil if you have:
- An allergy to Etripamil or any of the ingredients in the nasal spray.
- Moderate to severe heart failure.
- Certain abnormal heart rhythm patterns, including Wolff-Parkinson-White (WPW) syndrome, Lown-Ganong-Levine (LGL) syndrome, or a "delta wave" on an EKG.
- Sick sinus syndrome, unless you have a permanent pacemaker.
- A heart rhythm problem called second degree or higher heart block.
Cautions
Pregnancy: It is not known if Etripamil will harm an unborn baby. Tell your health care provider if you are pregnant or plan to become pregnant.
Lactation: It is unknown if Etripamil passes into breast milk. However, because of the risk of serious side effects like low blood pressure or a slow heartbeat in a nursing baby, you should stop breastfeeding and pump and throw away your breast milk for 12 hours after using this medicine.
