uses
What is fosaprepitant used for?Fosarepitant is commonly used to prevent nausea and vomiting that is caused by chemotherapy.Fosaprepitant may also be used for other conditions as determined by your health care provider.How does fosaprepitant work (mechanism of action)?Fosaprepitant is a type of medicine known as an antiemetic (anti-nausea medicine). It turns into another medicine, called aprepitant, in the body. Aprepitant works by preventing a substance in the brain from binding to neurokinin-1 (NK1) receptors. This helps suppress the vomiting reflex.How is fosaprepitant supplied (dosage forms)?Brands and other namesEmend injectionFocinvezDosage forms and strengthsFosaprepitant is available in an injectable form that is given by a health care provider.
See also : Aprepitant (Aponvie, Cinvanti,Emend oral)How should I store fosaprepitant?Fosaprepitant is usually given by a health care provider in a hospital or clinic.
You will not store it at home.how to use
liquid that is injected into a blood vessel
drug interactions
Does fosaprepitant interact with foods or drinks?There are no known interactions between fosaprepitant and foods or drinks.It is unknown if drinking alcohol will affect fosaprepitant.Does fosaprepitant interact with other medicines (drug interactions)?Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.In particular, make sure that you discuss if you are using any of the following before using fosaprepitant.A birth control pill, patch, vaginal ring, implant, injection, or intrauterine device (IUD) that contains hormonesPimozide, an antipsychotic medicine used to treat symptoms of Tourette syndromeWarfarin, which is a blood thinnerRifampin (Rifadin), which is a medicine commonly used to treat an infection called tuberculosisFluconazole (Diflucan), itraconazole (Sporanox, Tolsura), ketoconazole, posaconazole (Noxafil), or voriconazole (Vfend), which are used for fungal infectionsDiltiazem (Cardizem CD and others), which is a medicine used for high blood pressure and other conditionsA benzodiazepine, such as alprazolam or triazolam, which is a medicine used for anxiety, muscle spasms, or seizuresA corticosteroid, such as dexamethasone or methylprednisolone, which is a medicine for certain inflammatory conditionsClarithromycin, which is a medicine used for bacterial infectionsA protease inhibitor, such as nelfinavir (Viracept) or ritonavir (Norvir), which is a medicine commonly used to treat HIVNefazodone, which is a medicine used to treat depressionAny medicine for seizures, such as carbamazepine or phenytoinMany other medicines may alter the blood levels of fosaprepitant, and vice versa. Tell your health care provider about all medicines that you take or have recently taken.This may not be a complete list of medicines that can interact with fosaprepitant. Always check with your health care provider.
side effects
What are the most common side effects of fosaprepitant?The most common side effects of fosaprepitant are listed below. These side effects may vary based on your age. Tell your health care provider if you have any of these side effects that bother you.TirednessDiarrheaBlood disorders, including low white blood cell levels, low neutrophil levels (neutropenia), and low red blood cell levels WeaknessTingling, weakness, numbness, or pain in the arms or legsUpset stomachKidney or bladder infectionThere may be other side effects of fosaprepitant that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.What are the serious side effects of fosaprepitant?While less common, the most serious side effects of fosaprepitant are described below, along with what to do if they happen.Severe Allergic Reactions. Fosrepitant may cause allergic reactions, which can be serious. Get help right away if you have any of the following symptoms of a serious allergic reaction.Breathing problems or wheezingFast or weak heartbeatFever or general ill feelingSwollen lymph nodesSwelling of the face, lips, mouth, tongue, or throatTrouble swallowing or throat tightnessItching, skin rash, or pale red bumps on the skin called hivesSkin peeling or soresNausea or vomitingDizziness, feeling lightheaded, or faintingFlushing or skin rednessStomach crampsJoint painInfusion Reactions. Fosaprepitant can cause infusion reactions that can be serious. The risk of these reactions may be higher if you are also receiving certain types of chemotherapy. Tell your health care provider right away if you have any reactions or skin changes where you receive your infusion, such as pain, swelling, spots, lumps, bruising, or discoloration or redness at the infusion site.
overdose and misseddose
What should I do if I accidentally use too much fosaprepitant?If you or someone else has used too much fosaprepitant, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.What should I do if I miss a dose of fosaprepitant?Fosaprepitant is usually given by a health care provider in a hospital. Your health care provider will make sure you are receiving fosaprepitant as scheduled. If you miss an appointment, call to make another appointment as soon as possible.Â
warnings and Precautions
Who should not use fosaprepitant?Allergies to Ingredients. People who are allergic to any of the following should not use fosaprepitant.AprepitantEmendFocinvezFosaprepitantAny of the ingredients in the specific product dispensedYour pharmacist can tell you all of the ingredients in the specific fosaprepitant products they stock.Drug Interactions. Fosaprepitant should not be used while you are using certain other medicines. Before using fosaprepitant, tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.What should I know about fosaprepitant before using it?Fosaprepitant is usually given by a health care provider in a hospital or clinic. Do not use fosaprepitant unless it has been prescribed to you by a health care provider. Fosaprepitant may make certain types of birth control not work as well. If you are using a form of birth control that contains hormones (such as a pill, patch, or vaginal ring) to prevent pregnancy, you should use backup nonhormonal birth control (such as condoms) while using fosaprepitant and for one month after your last dose. What should I tell my health care provider before using fosaprepitant?Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if fosaprepitant is right for you.In particular, make sure that you discuss any of the following.Liver Problems. It is unknown if or how fosaprepitant may affect you if you have severe liver problems. Tell your health care provider about any prior or current liver problems.Pregnancy. It is not known if or how fosaprepitant could affect pregnancy or harm an unborn baby. Tell your health care provider if you are or plan to become pregnant.Breastfeeding. It is not known if fosaprepitant passes into breast milk. Tell your health care provider if you are breastfeeding or plan to breastfeed. Your health care provider will advise you if you should use aprepitant while breastfeeding.
about
Fosarepitant is used to prevent nausea and vomiting. Common side effects include tiredness, diarrhea, or weakness. Fosaprepitant is given by a health care provider as an infusion into a vein (IV). Tell your health care provider right away if you develop a rash or have any reactions or skin changes where you receive your infusion, such as pain, swelling, or discoloration or redness at the infusion site.