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Pristiq Drug and Medication User Reviews on RxList

DESVENLAFAXINE EXTENDED-RELEASE - ORAL

USER REVIEWS

Comment from: DavetheDad 45-54 Transgender 10 years or more Caregiver Published: June 29

I took Pristiq for over 10 years. It was a great benefit in the early years and over time became a problem. Dosage was increased over the years to combat diminishing returns. Side effects included severe constipation from time to time, restless leg Syndrome and impacted my central sleep apnoea. I have now been off Pristiq for 6 months and although it was very good for me initially, it became a problem and I am now fearful of trying any other anti-depressants. My Advice from my experience - try it, but put a definite time limit on its use. 6 months to 2 years and no more. Make sure you can deal with restless leg syndrome and constipation.

Comment from: DavetheDad 45-54 Transgender 10 years or more Caregiver Published: June 29

I took Pristiq for over 10 years. It was a great benefit in the early years and over time became a problem. Dosage was increased over the years to combat diminishing returns. Side effects included severe constipation from time to time, restless leg Syndrome and impacted my central sleep apnoea. I have now been off Pristiq for 6 months and although it was very good for me initially, it became a problem and I am now fearful of trying any other anti-depressants. My Advice from my experience - try it, but put a definite time limit on its use. 6 months to 2 years and no more. Make sure you can deal with restless leg syndrome and constipation.

Comment from: Wendy 45-54 Transgender 2 to less than 5 years Caregiver Published: June 25

I have been on antidepressants since the 1980s for depression and anxiety. This is the best one yet. Recently, my husband tried and failed on other meds. He was switched to desvenlafaxine and he's back to his normal self. I'm very happy.

Related Reading: depression | anxiety

SLIDESHOW

Learn to Spot Depression: Symptoms, Warning Signs, Medication See Slideshow
Comment from: DavetheDad 45-54 Transgender 10 years or more Caregiver Published: June 29

I took Pristiq for over 10 years. It was a great benefit in the early years and over time became a problem. Dosage was increased over the years to combat diminishing returns. Side effects included severe constipation from time to time, restless leg Syndrome and impacted my central sleep apnoea. I have now been off Pristiq for 6 months and although it was very good for me initially, it became a problem and I am now fearful of trying any other anti-depressants. My Advice from my experience - try it, but put a definite time limit on its use. 6 months to 2 years and no more. Make sure you can deal with restless leg syndrome and constipation.

Comment from: Wendy 45-54 Transgender 2 to less than 5 years Caregiver Published: June 25

I have been on antidepressants since the 1980s for depression and anxiety. This is the best one yet. Recently, my husband tried and failed on other meds. He was switched to desvenlafaxine and he's back to his normal self. I'm very happy.

Related Reading: depression | anxiety

Comment from: maura 19-24 Transgender 1 to 6 months Caregiver Published: June 09

worked extremely quickly, and had a massive impact. each med does something different for each person, it is not one size fits all. this one was absolutely amazing for me.

Comment from: DavetheDad 45-54 Transgender 10 years or more Caregiver Published: June 29

I took Pristiq for over 10 years. It was a great benefit in the early years and over time became a problem. Dosage was increased over the years to combat diminishing returns. Side effects included severe constipation from time to time, restless leg Syndrome and impacted my central sleep apnoea. I have now been off Pristiq for 6 months and although it was very good for me initially, it became a problem and I am now fearful of trying any other anti-depressants. My Advice from my experience - try it, but put a definite time limit on its use. 6 months to 2 years and no more. Make sure you can deal with restless leg syndrome and constipation.

Comment from: Wendy 45-54 Transgender 2 to less than 5 years Caregiver Published: June 25

I have been on antidepressants since the 1980s for depression and anxiety. This is the best one yet. Recently, my husband tried and failed on other meds. He was switched to desvenlafaxine and he's back to his normal self. I'm very happy.

Related Reading: depression | anxiety

Comment from: maura 19-24 Transgender 1 to 6 months Caregiver Published: June 09

worked extremely quickly, and had a massive impact. each med does something different for each person, it is not one size fits all. this one was absolutely amazing for me.

Comment from: NC 25-34 Transgender 2 to less than 5 years Caregiver Published: June 04

I've had doctors try every med under the sun for my major depressive disorder. Nothing ever came close to helping me until a mental health professional tried Pristiq. It was the difference between night and day, and honestly I'm so grateful to finally have a med work. I'm no longer overwhelmed by depression which is saying a lot because I've been battling it for decades. Do not miss a dose though, makes me feel like everything is moving constantly. This med changed my life, and I didn't want to be dependent on meds, but I'll never be without this one again. I can't stress enough how much good this has done for my life.

Related Reading: mental health | pristiq | depression

QUESTION

Depression is a(n) __________ . See Answer
Comment from: DavetheDad 45-54 Transgender 10 years or more Caregiver Published: June 29

I took Pristiq for over 10 years. It was a great benefit in the early years and over time became a problem. Dosage was increased over the years to combat diminishing returns. Side effects included severe constipation from time to time, restless leg Syndrome and impacted my central sleep apnoea. I have now been off Pristiq for 6 months and although it was very good for me initially, it became a problem and I am now fearful of trying any other anti-depressants. My Advice from my experience - try it, but put a definite time limit on its use. 6 months to 2 years and no more. Make sure you can deal with restless leg syndrome and constipation.

Comment from: Wendy 45-54 Transgender 2 to less than 5 years Caregiver Published: June 25

I have been on antidepressants since the 1980s for depression and anxiety. This is the best one yet. Recently, my husband tried and failed on other meds. He was switched to desvenlafaxine and he's back to his normal self. I'm very happy.

Related Reading: depression | anxiety

Comment from: maura 19-24 Transgender 1 to 6 months Caregiver Published: June 09

worked extremely quickly, and had a massive impact. each med does something different for each person, it is not one size fits all. this one was absolutely amazing for me.

Comment from: NC 25-34 Transgender 2 to less than 5 years Caregiver Published: June 04

I've had doctors try every med under the sun for my major depressive disorder. Nothing ever came close to helping me until a mental health professional tried Pristiq. It was the difference between night and day, and honestly I'm so grateful to finally have a med work. I'm no longer overwhelmed by depression which is saying a lot because I've been battling it for decades. Do not miss a dose though, makes me feel like everything is moving constantly. This med changed my life, and I didn't want to be dependent on meds, but I'll never be without this one again. I can't stress enough how much good this has done for my life.

Related Reading: mental health | pristiq | depression

Comment from: Kris 19-24 Transgender 2 to less than 5 years Caregiver Published: April 29

I went from feeling like a no-energy zombie to feeling like "my old self" that I had lost for years. It does disturb my sleep alittle but not to the point of fatigue. I take a low dose Seroquel for that. I am 75 yrs. old

Related Reading: seroquel

Comment from: DavetheDad 45-54 Transgender 10 years or more Caregiver Published: June 29

I took Pristiq for over 10 years. It was a great benefit in the early years and over time became a problem. Dosage was increased over the years to combat diminishing returns. Side effects included severe constipation from time to time, restless leg Syndrome and impacted my central sleep apnoea. I have now been off Pristiq for 6 months and although it was very good for me initially, it became a problem and I am now fearful of trying any other anti-depressants. My Advice from my experience - try it, but put a definite time limit on its use. 6 months to 2 years and no more. Make sure you can deal with restless leg syndrome and constipation.

Comment from: Wendy 45-54 Transgender 2 to less than 5 years Caregiver Published: June 25

I have been on antidepressants since the 1980s for depression and anxiety. This is the best one yet. Recently, my husband tried and failed on other meds. He was switched to desvenlafaxine and he's back to his normal self. I'm very happy.

Related Reading: depression | anxiety

Comment from: maura 19-24 Transgender 1 to 6 months Caregiver Published: June 09

worked extremely quickly, and had a massive impact. each med does something different for each person, it is not one size fits all. this one was absolutely amazing for me.

Comment from: NC 25-34 Transgender 2 to less than 5 years Caregiver Published: June 04

I've had doctors try every med under the sun for my major depressive disorder. Nothing ever came close to helping me until a mental health professional tried Pristiq. It was the difference between night and day, and honestly I'm so grateful to finally have a med work. I'm no longer overwhelmed by depression which is saying a lot because I've been battling it for decades. Do not miss a dose though, makes me feel like everything is moving constantly. This med changed my life, and I didn't want to be dependent on meds, but I'll never be without this one again. I can't stress enough how much good this has done for my life.

Related Reading: mental health | pristiq | depression

Comment from: Kris 19-24 Transgender 2 to less than 5 years Caregiver Published: April 29

I went from feeling like a no-energy zombie to feeling like "my old self" that I had lost for years. It does disturb my sleep alittle but not to the point of fatigue. I take a low dose Seroquel for that. I am 75 yrs. old

Related Reading: seroquel

Comment from: Janet 45-54 Transgender 1 to 6 months Caregiver Published: April 27

Pristiq changed my life. I have had anxiety off and on for 12 years and resisted prescription medications. Sometimes my anxiety would last for 3 months and sometimes for 3 days. This last time it lasted for 6 months. My doctor recommended Pristiq and I resisted even then for 3 more months. I analyzed every drug on line and was scared to take anything because each drug had issues with some people. Finally one day I had enough and told myself I had to try something. I was in "analysis paralysis" according to a friend. For the first 10 days I stressed and stressed and felt like I should not have started this. I had a tremor, headaches, still had anxiety and other side effects. However about day 11 I noticed a sharp change for the better and after about another 10 days even more. For the first time in a long time I was in a good mood for the majority of the day. I also have insomnia and take different meds for that....I was able to decrease my insomnia meds and that makes me even happier

Related Reading: pristiq | anxiety | insomnia

Comment from: DavetheDad 45-54 Transgender 10 years or more Caregiver Published: June 29

I took Pristiq for over 10 years. It was a great benefit in the early years and over time became a problem. Dosage was increased over the years to combat diminishing returns. Side effects included severe constipation from time to time, restless leg Syndrome and impacted my central sleep apnoea. I have now been off Pristiq for 6 months and although it was very good for me initially, it became a problem and I am now fearful of trying any other anti-depressants. My Advice from my experience - try it, but put a definite time limit on its use. 6 months to 2 years and no more. Make sure you can deal with restless leg syndrome and constipation.

Comment from: Wendy 45-54 Transgender 2 to less than 5 years Caregiver Published: June 25

I have been on antidepressants since the 1980s for depression and anxiety. This is the best one yet. Recently, my husband tried and failed on other meds. He was switched to desvenlafaxine and he's back to his normal self. I'm very happy.

Related Reading: depression | anxiety

Comment from: maura 19-24 Transgender 1 to 6 months Caregiver Published: June 09

worked extremely quickly, and had a massive impact. each med does something different for each person, it is not one size fits all. this one was absolutely amazing for me.

Comment from: NC 25-34 Transgender 2 to less than 5 years Caregiver Published: June 04

I've had doctors try every med under the sun for my major depressive disorder. Nothing ever came close to helping me until a mental health professional tried Pristiq. It was the difference between night and day, and honestly I'm so grateful to finally have a med work. I'm no longer overwhelmed by depression which is saying a lot because I've been battling it for decades. Do not miss a dose though, makes me feel like everything is moving constantly. This med changed my life, and I didn't want to be dependent on meds, but I'll never be without this one again. I can't stress enough how much good this has done for my life.

Related Reading: mental health | pristiq | depression

Comment from: Kris 19-24 Transgender 2 to less than 5 years Caregiver Published: April 29

I went from feeling like a no-energy zombie to feeling like "my old self" that I had lost for years. It does disturb my sleep alittle but not to the point of fatigue. I take a low dose Seroquel for that. I am 75 yrs. old

Related Reading: seroquel

Comment from: Janet 45-54 Transgender 1 to 6 months Caregiver Published: April 27

Pristiq changed my life. I have had anxiety off and on for 12 years and resisted prescription medications. Sometimes my anxiety would last for 3 months and sometimes for 3 days. This last time it lasted for 6 months. My doctor recommended Pristiq and I resisted even then for 3 more months. I analyzed every drug on line and was scared to take anything because each drug had issues with some people. Finally one day I had enough and told myself I had to try something. I was in "analysis paralysis" according to a friend. For the first 10 days I stressed and stressed and felt like I should not have started this. I had a tremor, headaches, still had anxiety and other side effects. However about day 11 I noticed a sharp change for the better and after about another 10 days even more. For the first time in a long time I was in a good mood for the majority of the day. I also have insomnia and take different meds for that....I was able to decrease my insomnia meds and that makes me even happier

Related Reading: pristiq | anxiety | insomnia

Comment from: littledove 19-24 Transgender 6 months to less than 1 year Caregiver Published: April 24

I need to preface this by saying I took a birth control called Yaz for a week and it gave me every symptom of a panic disorder. Lexapro and zoloft didn’t work; I wasn’t depressed at 22, but I was so anxious I couldn’t leave my house. I felt panicky, like I had to leave wherever I was the second I got that feeling. Doctor put me on 25mgs of Pristiq since I was having panic attacks every single day. I couldn’t hold a job, I had to stop going to classes. It was awful. I took the pristiq in the morning since I’ve had issues with insomnia in the past, and in the afternoon i started having a panic attack, but right before that high point of anxiety, I slowly felt myself come back. I got diagnosed with ADHD a few months later and was told the Pristiq also helps symptoms of ADHD and that it’s VERY likely my anxiety stems from my ADHD but was aggravated by the change in hormones from the birth control. So, not a magical pill, but if your problem is anxiety from your flight or fight system, I suggest trying this. Absolutely changed my life.

Related Reading: yaz | lexapro | zoloft

Comment from: Benito 13-18 Transgender 1 to 6 months Caregiver Published: April 18

I've struggled with crippling episodes of Depersonalization/Derealization. Since starting this it has relieved some of my symptoms and overall improved my quality of life. Keep hope and keep trying to get better, it will!

Comment from: Benito 13-18 Transgender 1 to 6 months Caregiver Published: April 18

I've struggled with crippling episodes of Depersonalization/Derealization. Since starting this it has relieved some of my symptoms and overall improved my quality of life. Keep hope and keep trying to get better, it will!

Comment from: NebraskaGuy91 25-34 Transgender 10 years or more Caregiver Published: March 25

I’ve been on Pristiq for 10+ years now & it’s worked the best out of the many different drugs I’ve tried for my depression.

Related Reading: pristiq | depression

Comment from: Benito 13-18 Transgender 1 to 6 months Caregiver Published: April 18

I've struggled with crippling episodes of Depersonalization/Derealization. Since starting this it has relieved some of my symptoms and overall improved my quality of life. Keep hope and keep trying to get better, it will!

Comment from: NebraskaGuy91 25-34 Transgender 10 years or more Caregiver Published: March 25

I’ve been on Pristiq for 10+ years now & it’s worked the best out of the many different drugs I’ve tried for my depression.

Related Reading: pristiq | depression

Comment from: RH 45-54 Transgender Caregiver Published: March 18

What's the "End Game" for taking this? is it to always have to rely on this because I cant be Undepressed? I get to live a medicated half life? There's no surgery to relieve me of this condition. I cant talk my way out of it . So I guess in order to have a life I get to have a "fake" life/ medicated life with side effects, the issue is from within not a condition that can be "cut out" or operated on

SLIDESHOW

Learn to Spot Depression: Symptoms, Warning Signs, Medication See Slideshow
Comment from: Benito 13-18 Transgender 1 to 6 months Caregiver Published: April 18

I've struggled with crippling episodes of Depersonalization/Derealization. Since starting this it has relieved some of my symptoms and overall improved my quality of life. Keep hope and keep trying to get better, it will!

Comment from: NebraskaGuy91 25-34 Transgender 10 years or more Caregiver Published: March 25

I’ve been on Pristiq for 10+ years now & it’s worked the best out of the many different drugs I’ve tried for my depression.

Related Reading: pristiq | depression

Comment from: RH 45-54 Transgender Caregiver Published: March 18

What's the "End Game" for taking this? is it to always have to rely on this because I cant be Undepressed? I get to live a medicated half life? There's no surgery to relieve me of this condition. I cant talk my way out of it . So I guess in order to have a life I get to have a "fake" life/ medicated life with side effects, the issue is from within not a condition that can be "cut out" or operated on

Comment from: Transgender Caregiver Published: March 04

All side effects. Feels like poison. Can't sleep. This drug is the worst of all the ones I've tried, including Zoloft.

Related Reading: zoloft

Comment from: Benito 13-18 Transgender 1 to 6 months Caregiver Published: April 18

I've struggled with crippling episodes of Depersonalization/Derealization. Since starting this it has relieved some of my symptoms and overall improved my quality of life. Keep hope and keep trying to get better, it will!

Comment from: NebraskaGuy91 25-34 Transgender 10 years or more Caregiver Published: March 25

I’ve been on Pristiq for 10+ years now & it’s worked the best out of the many different drugs I’ve tried for my depression.

Related Reading: pristiq | depression

Comment from: RH 45-54 Transgender Caregiver Published: March 18

What's the "End Game" for taking this? is it to always have to rely on this because I cant be Undepressed? I get to live a medicated half life? There's no surgery to relieve me of this condition. I cant talk my way out of it . So I guess in order to have a life I get to have a "fake" life/ medicated life with side effects, the issue is from within not a condition that can be "cut out" or operated on

Comment from: Transgender Caregiver Published: March 04

All side effects. Feels like poison. Can't sleep. This drug is the worst of all the ones I've tried, including Zoloft.

Related Reading: zoloft

Comment from: Carrie 35-44 Transgender 1 to 6 months Caregiver Published: March 03

Before you take every comment on here to heart, remember that everyone's experience is different because every BODY is different. I had tried Prozac and Lexapro before trying Pristiq, and those "horrid side effects" people talked about with this medicine is what I experienced with Lexapro and Prozac. They just weren't for me. I started taking Pristiq 4 weeks ago, and I can't tell you how HAPPY I am that I made the switch. I finally don't feel exhausted all day every day; I finally don't have suicidal ideation on a regular basis, or get depressed from hearing a certain song or the weather changing; I feel so much more confident, energized, and happy! It really has been a saving grace for me. The moral of the story here is that if this doesn't work for you, check on other options! And if anything, please talk to a psychiatrist! I went to my GP for the other two medications, and they clearly didn't understand my needs. My psychiatrist got it right, and I am so grateful for that!

Related Reading: prozac | lexapro | pristiq

Comment from: Benito 13-18 Transgender 1 to 6 months Caregiver Published: April 18

I've struggled with crippling episodes of Depersonalization/Derealization. Since starting this it has relieved some of my symptoms and overall improved my quality of life. Keep hope and keep trying to get better, it will!

Comment from: NebraskaGuy91 25-34 Transgender 10 years or more Caregiver Published: March 25

I’ve been on Pristiq for 10+ years now & it’s worked the best out of the many different drugs I’ve tried for my depression.

Related Reading: pristiq | depression

Comment from: RH 45-54 Transgender Caregiver Published: March 18

What's the "End Game" for taking this? is it to always have to rely on this because I cant be Undepressed? I get to live a medicated half life? There's no surgery to relieve me of this condition. I cant talk my way out of it . So I guess in order to have a life I get to have a "fake" life/ medicated life with side effects, the issue is from within not a condition that can be "cut out" or operated on

Comment from: Transgender Caregiver Published: March 04

All side effects. Feels like poison. Can't sleep. This drug is the worst of all the ones I've tried, including Zoloft.

Related Reading: zoloft

Comment from: Carrie 35-44 Transgender 1 to 6 months Caregiver Published: March 03

Before you take every comment on here to heart, remember that everyone's experience is different because every BODY is different. I had tried Prozac and Lexapro before trying Pristiq, and those "horrid side effects" people talked about with this medicine is what I experienced with Lexapro and Prozac. They just weren't for me. I started taking Pristiq 4 weeks ago, and I can't tell you how HAPPY I am that I made the switch. I finally don't feel exhausted all day every day; I finally don't have suicidal ideation on a regular basis, or get depressed from hearing a certain song or the weather changing; I feel so much more confident, energized, and happy! It really has been a saving grace for me. The moral of the story here is that if this doesn't work for you, check on other options! And if anything, please talk to a psychiatrist! I went to my GP for the other two medications, and they clearly didn't understand my needs. My psychiatrist got it right, and I am so grateful for that!

Related Reading: prozac | lexapro | pristiq

Comment from: Crazy2 55-64 Transgender less than 1 month Caregiver Published: March 03

None of the benefits, but I got all the terrible side-effects. Worst medication I've ever taken.

Comment from: Benito 13-18 Transgender 1 to 6 months Caregiver Published: April 18

I've struggled with crippling episodes of Depersonalization/Derealization. Since starting this it has relieved some of my symptoms and overall improved my quality of life. Keep hope and keep trying to get better, it will!

Comment from: NebraskaGuy91 25-34 Transgender 10 years or more Caregiver Published: March 25

I’ve been on Pristiq for 10+ years now & it’s worked the best out of the many different drugs I’ve tried for my depression.

Related Reading: pristiq | depression

Comment from: RH 45-54 Transgender Caregiver Published: March 18

What's the "End Game" for taking this? is it to always have to rely on this because I cant be Undepressed? I get to live a medicated half life? There's no surgery to relieve me of this condition. I cant talk my way out of it . So I guess in order to have a life I get to have a "fake" life/ medicated life with side effects, the issue is from within not a condition that can be "cut out" or operated on

Comment from: Transgender Caregiver Published: March 04

All side effects. Feels like poison. Can't sleep. This drug is the worst of all the ones I've tried, including Zoloft.

Related Reading: zoloft

Comment from: Carrie 35-44 Transgender 1 to 6 months Caregiver Published: March 03

Before you take every comment on here to heart, remember that everyone's experience is different because every BODY is different. I had tried Prozac and Lexapro before trying Pristiq, and those "horrid side effects" people talked about with this medicine is what I experienced with Lexapro and Prozac. They just weren't for me. I started taking Pristiq 4 weeks ago, and I can't tell you how HAPPY I am that I made the switch. I finally don't feel exhausted all day every day; I finally don't have suicidal ideation on a regular basis, or get depressed from hearing a certain song or the weather changing; I feel so much more confident, energized, and happy! It really has been a saving grace for me. The moral of the story here is that if this doesn't work for you, check on other options! And if anything, please talk to a psychiatrist! I went to my GP for the other two medications, and they clearly didn't understand my needs. My psychiatrist got it right, and I am so grateful for that!

Related Reading: prozac | lexapro | pristiq

Comment from: Crazy2 55-64 Transgender less than 1 month Caregiver Published: March 03

None of the benefits, but I got all the terrible side-effects. Worst medication I've ever taken.

Comment from: Mona 35-44 Transgender 1 to less than 2 years Caregiver Published: February 01

I struggled with debilitating anxiety and panic attacks throughout my life. Having had tried most antidepressants and even some anti psychotic meds before without much relief, I was very sceptical to try Pristiq. Not going to lie, the heightened anxiety in the first 4 weeks made me almost quit the treatment. I am glad that I stuck with it though, this is the most balanced and grounded I have ever felt and I have handled some of the most stressful times in my life with so much ease recently. I am so grateful that we finally found something that works for me.

Related Reading: anxiety | panic attacks | pristiq

Comment from: Benito 13-18 Transgender 1 to 6 months Caregiver Published: April 18

I've struggled with crippling episodes of Depersonalization/Derealization. Since starting this it has relieved some of my symptoms and overall improved my quality of life. Keep hope and keep trying to get better, it will!

Comment from: NebraskaGuy91 25-34 Transgender 10 years or more Caregiver Published: March 25

I’ve been on Pristiq for 10+ years now & it’s worked the best out of the many different drugs I’ve tried for my depression.

Related Reading: pristiq | depression

Comment from: RH 45-54 Transgender Caregiver Published: March 18

What's the "End Game" for taking this? is it to always have to rely on this because I cant be Undepressed? I get to live a medicated half life? There's no surgery to relieve me of this condition. I cant talk my way out of it . So I guess in order to have a life I get to have a "fake" life/ medicated life with side effects, the issue is from within not a condition that can be "cut out" or operated on

Comment from: Transgender Caregiver Published: March 04

All side effects. Feels like poison. Can't sleep. This drug is the worst of all the ones I've tried, including Zoloft.

Related Reading: zoloft

Comment from: Carrie 35-44 Transgender 1 to 6 months Caregiver Published: March 03

Before you take every comment on here to heart, remember that everyone's experience is different because every BODY is different. I had tried Prozac and Lexapro before trying Pristiq, and those "horrid side effects" people talked about with this medicine is what I experienced with Lexapro and Prozac. They just weren't for me. I started taking Pristiq 4 weeks ago, and I can't tell you how HAPPY I am that I made the switch. I finally don't feel exhausted all day every day; I finally don't have suicidal ideation on a regular basis, or get depressed from hearing a certain song or the weather changing; I feel so much more confident, energized, and happy! It really has been a saving grace for me. The moral of the story here is that if this doesn't work for you, check on other options! And if anything, please talk to a psychiatrist! I went to my GP for the other two medications, and they clearly didn't understand my needs. My psychiatrist got it right, and I am so grateful for that!

Related Reading: prozac | lexapro | pristiq

Comment from: Crazy2 55-64 Transgender less than 1 month Caregiver Published: March 03

None of the benefits, but I got all the terrible side-effects. Worst medication I've ever taken.

Comment from: Mona 35-44 Transgender 1 to less than 2 years Caregiver Published: February 01

I struggled with debilitating anxiety and panic attacks throughout my life. Having had tried most antidepressants and even some anti psychotic meds before without much relief, I was very sceptical to try Pristiq. Not going to lie, the heightened anxiety in the first 4 weeks made me almost quit the treatment. I am glad that I stuck with it though, this is the most balanced and grounded I have ever felt and I have handled some of the most stressful times in my life with so much ease recently. I am so grateful that we finally found something that works for me.

Related Reading: anxiety | panic attacks | pristiq

Comment from: Brett 45-54 Transgender 1 to 6 months Caregiver Published: January 31

This medication had no positive benefits.

Comment from: Benito 13-18 Transgender 1 to 6 months Caregiver Published: April 18

I've struggled with crippling episodes of Depersonalization/Derealization. Since starting this it has relieved some of my symptoms and overall improved my quality of life. Keep hope and keep trying to get better, it will!

Comment from: NebraskaGuy91 25-34 Transgender 10 years or more Caregiver Published: March 25

I’ve been on Pristiq for 10+ years now & it’s worked the best out of the many different drugs I’ve tried for my depression.

Related Reading: pristiq | depression

Comment from: RH 45-54 Transgender Caregiver Published: March 18

What's the "End Game" for taking this? is it to always have to rely on this because I cant be Undepressed? I get to live a medicated half life? There's no surgery to relieve me of this condition. I cant talk my way out of it . So I guess in order to have a life I get to have a "fake" life/ medicated life with side effects, the issue is from within not a condition that can be "cut out" or operated on

Comment from: Transgender Caregiver Published: March 04

All side effects. Feels like poison. Can't sleep. This drug is the worst of all the ones I've tried, including Zoloft.

Related Reading: zoloft

Comment from: Carrie 35-44 Transgender 1 to 6 months Caregiver Published: March 03

Before you take every comment on here to heart, remember that everyone's experience is different because every BODY is different. I had tried Prozac and Lexapro before trying Pristiq, and those "horrid side effects" people talked about with this medicine is what I experienced with Lexapro and Prozac. They just weren't for me. I started taking Pristiq 4 weeks ago, and I can't tell you how HAPPY I am that I made the switch. I finally don't feel exhausted all day every day; I finally don't have suicidal ideation on a regular basis, or get depressed from hearing a certain song or the weather changing; I feel so much more confident, energized, and happy! It really has been a saving grace for me. The moral of the story here is that if this doesn't work for you, check on other options! And if anything, please talk to a psychiatrist! I went to my GP for the other two medications, and they clearly didn't understand my needs. My psychiatrist got it right, and I am so grateful for that!

Related Reading: prozac | lexapro | pristiq

Comment from: Crazy2 55-64 Transgender less than 1 month Caregiver Published: March 03

None of the benefits, but I got all the terrible side-effects. Worst medication I've ever taken.

Comment from: Mona 35-44 Transgender 1 to less than 2 years Caregiver Published: February 01

I struggled with debilitating anxiety and panic attacks throughout my life. Having had tried most antidepressants and even some anti psychotic meds before without much relief, I was very sceptical to try Pristiq. Not going to lie, the heightened anxiety in the first 4 weeks made me almost quit the treatment. I am glad that I stuck with it though, this is the most balanced and grounded I have ever felt and I have handled some of the most stressful times in my life with so much ease recently. I am so grateful that we finally found something that works for me.

Related Reading: anxiety | panic attacks | pristiq

Comment from: Brett 45-54 Transgender 1 to 6 months Caregiver Published: January 31

This medication had no positive benefits.

Comment from: Anna 55-64 Transgender 1 to less than 2 years Caregiver Published: January 28

I was on Lexapro for 11 yrs and went off when I retired. I crashed a year later. I was prescribed this and honestly the same day I felt the change. it has been amazing for me. yes I still have "down"days but I can get out of it easily with a walk. I love this pill and will never go off. I have energy, no weight gain (unless I have a few weeks of overeating), level mood and I feel normal.

Related Reading: lexapro

Comment from: DougZ 25-34 Transgender 1 to less than 2 years Caregiver Published: January 25

I've been on and off of anti depressants for over 10 years and this is the first SNRI that I have taken. It has been a little over a year since starting it and it has changed my life. I notice no sexual issues as I have in the past, and my day to day life is quite bearable - no major depressive issues as long as I don't miss a day. I've noticed that it is best for me to take it a few hours before bed. I do notice the next day if I have forgotten to take a pill as I will get very emotional and slightly dizzy.

Comment from: DougZ 25-34 Transgender 1 to less than 2 years Caregiver Published: January 25

I've been on and off of anti depressants for over 10 years and this is the first SNRI that I have taken. It has been a little over a year since starting it and it has changed my life. I notice no sexual issues as I have in the past, and my day to day life is quite bearable - no major depressive issues as long as I don't miss a day. I've noticed that it is best for me to take it a few hours before bed. I do notice the next day if I have forgotten to take a pill as I will get very emotional and slightly dizzy.

Comment from: Here4it333 35-44 Transgender less than 1 month Caregiver Published: December 17

I’ve been on a lot of different medications. I experience side effects very easily which is why I was put on pristiq. I only made it two days because the side effects were insane. I felt like I was on adderall and sleep medication all at the same time. So much energy, but so tired. On day two, I couldn’t even get off the couch. My anxiety was so bad. I had a migraine and terrible nausea. When I woke up on day 3, I felt like my brain had been abused and made the decision to give it a break. I don’t doubt this works for people, but it definitely wasn’t for me.

Related Reading: pristiq | adderall | anxiety

Comment from: DougZ 25-34 Transgender 1 to less than 2 years Caregiver Published: January 25

I've been on and off of anti depressants for over 10 years and this is the first SNRI that I have taken. It has been a little over a year since starting it and it has changed my life. I notice no sexual issues as I have in the past, and my day to day life is quite bearable - no major depressive issues as long as I don't miss a day. I've noticed that it is best for me to take it a few hours before bed. I do notice the next day if I have forgotten to take a pill as I will get very emotional and slightly dizzy.

Comment from: Here4it333 35-44 Transgender less than 1 month Caregiver Published: December 17

I’ve been on a lot of different medications. I experience side effects very easily which is why I was put on pristiq. I only made it two days because the side effects were insane. I felt like I was on adderall and sleep medication all at the same time. So much energy, but so tired. On day two, I couldn’t even get off the couch. My anxiety was so bad. I had a migraine and terrible nausea. When I woke up on day 3, I felt like my brain had been abused and made the decision to give it a break. I don’t doubt this works for people, but it definitely wasn’t for me.

Related Reading: pristiq | adderall | anxiety

Comment from: Hpbggg 35-44 Transgender 1 to 6 months Caregiver Published: December 14

40 pound weight gain in only four months despite increasing exercise and marathon training

Comment from: DougZ 25-34 Transgender 1 to less than 2 years Caregiver Published: January 25

I've been on and off of anti depressants for over 10 years and this is the first SNRI that I have taken. It has been a little over a year since starting it and it has changed my life. I notice no sexual issues as I have in the past, and my day to day life is quite bearable - no major depressive issues as long as I don't miss a day. I've noticed that it is best for me to take it a few hours before bed. I do notice the next day if I have forgotten to take a pill as I will get very emotional and slightly dizzy.

Comment from: Here4it333 35-44 Transgender less than 1 month Caregiver Published: December 17

I’ve been on a lot of different medications. I experience side effects very easily which is why I was put on pristiq. I only made it two days because the side effects were insane. I felt like I was on adderall and sleep medication all at the same time. So much energy, but so tired. On day two, I couldn’t even get off the couch. My anxiety was so bad. I had a migraine and terrible nausea. When I woke up on day 3, I felt like my brain had been abused and made the decision to give it a break. I don’t doubt this works for people, but it definitely wasn’t for me.

Related Reading: pristiq | adderall | anxiety

Comment from: Hpbggg 35-44 Transgender 1 to 6 months Caregiver Published: December 14

40 pound weight gain in only four months despite increasing exercise and marathon training

Comment from: Hava 65-74 Transgender 2 to less than 5 years Caregiver Published: December 02

Pristiq is one of the easiest most effective and quickly acting antidepressants I have ever used. And I have been taking many. No side effects, no weight gain, no anxiety, insomnia etc But it requires consistency. If you miss your dose you may feel somewhat under the weather, so be punctual!

Related Reading: pristiq | anxiety | insomnia

References
Medical Editor: John P. Cunha, DO, FACOEP