uses
What is Regranex used for?Regranex (becaplermin) is commonly used to treat open sores (ulcers) on your legs or feet in certain people with diabetes.Regranex may also be used for other conditions as determined by your health care provider.How does Regranex work (mechanism of action)?Regranex acts like a natural substance in your body that helps cells grow. It works by encouraging the growth of cells that are needed for repair and helping to form new tissue. This can help the sore or ulcer heal. How is Regranex supplied (dosage forms)?Brands and other namesRegranexDosage forms and strengths0.01% topical gelHow should I store Regranex?Regranex should be stored in the refrigerator, at temperatures of 36 F to 46 F (2 C to 8 C). Do not freeze it.
how to use
gel that is applied to the skin
drug interactions
Does Regranex interact with foods or drinks?There are no known interactions between Regranex and foods or drinks.It is unknown if drinking alcohol will affect Regranex.Does Regranex interact with other medicines (drug interactions)?There are no known interactions between Regranex and other medicines. Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.In particular, make sure that you discuss if you are using any other medicines that are applied to the skin.
side effects
What are the most common side effects of Regranex?The most common side effect of Regranex is a skin rash that may look red. Tell your health care provider if you have a rash that bothers you.There may be other side effects of Regranex that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088 (800-332-1088). In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.What are the serious side effects of Regranex?While less common, the most serious side effects of Regranex are described below, along with what to do if they happen.Severe Allergic Reactions. Regranex may cause allergic reactions, which can be serious. Stop using Regranex and get help right away if you have any of the following symptoms of a serious allergic reaction.Breathing problems or wheezingRacing heartFever or general ill feelingSwollen lymph nodesSwelling of the face, lips, mouth, tongue, or throatTrouble swallowing or throat tightnessItching, skin rash, or pale red bumps on the skin called hivesNausea or vomitingDizziness, feeling lightheaded, or faintingStomach crampsJoint painCancer. Some people have developed cancer while using Regranex, including cancers that were not near the area where the medicine was applied. Tell your health care provider about any new symptoms you may get, such as skin growths, lumps, or moles that change in appearance.Skin Reactions. Regranex can rarely cause skin-related side effects at or near the area where you apply the medicine. Tell your health care provider if you have a skin rash, irritation, or burning sensation that feels severe or does not go away.
overdose and misseddose
What should I do if I accidentally use too much Regranex?If you or someone else has used too much Regranex, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.What should I do if I miss a dose of Regranex?If you miss a dose, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only use the next dose. Do not use double or extra doses.
warnings and Precautions
Who should not use Regranex?Allergies to Ingredients. People who are allergic to any of the following should not use Regranex.RegranexBecaplerminAny of the ingredients in the specific product dispensedYour pharmacist can tell you all of the ingredients in Regranex.Skin Cancer. Regranex should not be used if you have skin cancer or tumors at the affected area. Using this medicine on areas with skin cancer could make it grow faster or larger.What should I know about Regranex before using it?Do not use Regranex unless it has been prescribed to you by a health care provider. Use it as prescribed.Do not share Regranex with other people, even if they have the same condition as you. It may harm them.Keep Regranex out of the reach of children. ​​Since this medicine should be kept in a refrigerator, take special care to keep it away from children who also use the refrigerator.Regranex is a topical gel that you apply to the skin. Read the instructions that come with this medicine and make sure you understand how to apply it properly.Your health care provider may also give you special instructions for taking good care of your sore or ulcer. This may include not walking or putting weight on the affected leg or foot. If you have any questions, talk to your health care provider.Wash your hands before and after applying Regranex to your skin. Be careful not to let the tip of the tube touch your ulcer, skin, or any other surfaces. Do not use Regranex near the mouth, eyes, or vagina.Keep all medical appointments to have your ulcer checked. As your ulcer changes in size, your health care provider may change the amount of Regranex you need to apply.What should I tell my health care provider before using Regranex?Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if Regranex is right for you.In particular, make sure that you discuss any of the following.Cancer. Regranex can raise the risk of cancer because it works by helping cells grow. Tell your health care provider if you have cancer or had it in the past. They can help them decide if Regranex is safe for you. Pregnancy. It is not known if or how Regranex could affect pregnancy or harm an unborn baby. Tell your health care provider if you are pregnant or plan to become pregnant.Breastfeeding. It is not known if Regranex passes into breast milk. Tell your health care provider if you are breastfeeding or plan to breastfeed.How can I get more information about Regranex?For more information about Regranex, you can visit the drugmaker’s website at www.smith-nephew.com or call them at 800-876-1261.Â
about
Regranex is used for diabetic sores or ulcers on the feet or legs. It helps heal the ulcer by promoting the growth of new tissue. The most common side effect is a skin rash. Less commonly, Regranex can cause skin irritation or may lead to skin cancer. Regranex is a topical gel that is applied to the affected area.