uses
What is ganirelix used for?Ganirelix is commonly used in fertility treatments. Specifically, it is used to delay your ovaries from releasing eggs too early (ovulation). Ganirelix may also be used for other conditions as determined by your healthcare provider.How does ganirelix work (mechanism of action)?Ganirelix is a type of medicine called a gonadotropin-releasing hormone (GnRH) antagonist. It blocks a specific hormone, called luteinizing hormone (LH), from being produced. LH tells the body to ovulate, so when ganirelix blocks LH, it prevents ovulation. This makes it possible for your healthcare provider to control when you ovulate for timing fertility treatments properly.How is ganirelix supplied (dosage forms)?Brands and other namesAntagonFyremadelDosage forms and strengths250 mcg/0.5 mL prefilled syringeHow should I store ganirelix?Ganirelix should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C) for shorter periods of time, such as when transporting it. Store in a cool, dry place and protect from light.
how to use
liquid that is injected under the skin
drug interactions
Does ganirelix interact with foods or drinks?There are no known interactions between ganirelix and foods or drinks.It is unknown if drinking alcohol will affect ganirelix.Does ganirelix interact with other medicines (drug interactions)?There are no known interactions between ganirelix and other medicines. Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.
side effects
What are the most common side effects of ganirelix?The most common side effects of ganirelix are listed below. Tell your healthcare provider if you have any of these side effects that bother you.Pelvic and stomach painHeadacheOvarian hyperstimulation syndrome (see below)Vaginal bleedingPain, discoloration or redness, or swelling at the injection siteNauseaThere may be other side effects of ganirelix that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.What are the serious side effects of ganirelix?While less common, the most serious side effects of ganirelix are described below, along with what to do if they happen.Severe Allergic Reactions. Ganirelix may cause allergic reactions, which can be serious. Stop using ganirelix and get help right away if you have any of the following symptoms of a serious allergic reaction.Breathing problems or wheezingRacing heartFever or general ill feelingSwollen lymph nodesSwelling of the face, lips, mouth, tongue, or throatTrouble swallowing or throat tightnessItching, skin rash, or pale red bumps on the skin called hivesNausea or vomitingDizziness, feeling lightheaded, or faintingStomach crampsJoint painOvarian Hyperstimulation Syndrome. Ganirelix can cause a condition called ovarian hyperstimulation syndrome, which can sometimes be serious. This condition causes the ovaries to become swollen and painful, and they may leak fluid. Stop using ganirelix and tell your healthcare provider right away if you have any of the following symptoms.Severe stomach pain or swellingTrouble breathingSevere nausea or vomitingRapid weight gainLess urine (pee) than usual
overdose and misseddose
What should I do if I accidentally use too much ganirelix?If you or someone else has used too much ganirelix, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.What should I do if I miss a dose of ganirelix?Ganirelix is meant to be used only as instructed for your treatment. Use it as your healthcare provider recommends. Do not use double or extra doses. If you miss a dose, call your healthcare provider right away to learn what to do.
warnings and Precautions
Who should not use ganirelix?Allergies to Ingredients. People who are allergic to any of the following should not use ganirelix.GanirelixFyremadelAny gonadotropin-releasing hormone (GnRH) medicineAny of the ingredients in the specific product dispensedYour pharmacist can tell you all of the ingredients in ganirelix products.Pregnancy. Do not use ganirelix If you are pregnant or think you are pregnant. If you become pregnant, contact your healthcare provider right away. See the Pregnancy section for more details.What should I know about ganirelix before using it?Do not use ganirelix unless it has been prescribed to you by a healthcare provider. Use it as prescribed.Do not share ganirelix with other people, even if they have the same condition as you. It may harm them.Keep ganirelix out of the reach of children.Before you start ganirelix, your healthcare provider will explain how long you will need to use it and the monitoring involved with your fertility treatment. Attend all check-ups and tests as directed.Follow the instructions your healthcare provider gives you in order to give yourself the injection. If you have questions about how to prepare or give yourself the injection, contact your healthcare provider before it is time to give your injection.What should I tell my healthcare provider before using ganirelix?Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if ganirelix is right for you.Pregnancy. Ganirelix may cause harm to an unborn baby and should not be used while you are pregnant. It is safe to be used in fertility treatments to become pregnant, but tell your healthcare provider if you become pregnant while using ganirelix.Breastfeeding. It is not known if ganirelix passes into breast milk. You should not use ganirelix while breastfeeding. Tell your healthcare provider if you are breastfeeding or plan to breastfeed.
about
Ganirelix is used in fertility treatments. Common side effects include pain, discoloration or redness, or swelling at the injection site. Nausea and headache can also occur. Ganirelix is an injection that you will give yourself after training from your healthcare provider.