Fluocinonide

Fluocinonide is a prescription cream corticosteroid, indicated for the relief of the inflammatory and hive manifestations of corticosteroid-responsive dermatoses.

Fluocinonide is available under the following different brand names: Lidemol, Lidex, Lyderm, Tiamol, Topactin, Topsyn, and Vanos.

Adult and Pediatric Dosages:

Cream

• 0.05%
• 0.1%

Ointment/Gel/Topical Solution

• 0.05%

Dosage Considerations – Should be Given as Follows:

Corticosteroid Responsive Dermatoses

Adult:

• Apply thin layer topically each day or every 12 hours to affected areas

Pediatric:

• Apply thin layer topically each day or every 12 hours to affected areas; limit to the minimum amount necessary for therapeutic efficacy

Psoriasis

• Apply thin layer topically each day or every 12 hours to affected areas

Atopic Dermatitis

• Apply thin layer topically each day to affected areas

Side effects of fluocinonide include:

• thinning of the skin
• stretch marks
• acne form lesions
• pigmentation changes
• hypothalamic-pituitary-adrenal suppression (with higher potency used over 2 weeks)
• high pressure within the skull
• loss of skin pigmentation
• skin softening and breakdown
• sweat rash or prickly heat
• infection of hair follicles
• high blood sugar (hyperglycemia)
• Cushing's syndrome
• Spider veins
• burning
• irritation
• glucose in the urine
• itching
• dryness
• abnormal hair growth
• facial rash
• contact allergy
• secondary infection

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

• Fluocinonide has no known severe interactions with other drugs.
• Fluocinonide has no known serious interactions with other drugs.
• Fluocinonide has no known moderate interactions with other drugs.
• Fluocinonide has no known mild interactions with other drugs.

This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns or for more information about this medicine.

Warnings

This medication contains fluocinonide. Do not take Lidemol, Lidex, Lyderm, Tiamol, Topactin, Topsyn, or Vanos if you are allergic to fluocinonide or any ingredients contained in this drug.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately

Contraindications

• Underlying infection (fungal, viral, tubercular skin lesions, or herpes simplex).
• Hypersensitivity
• Ophthalmic use

Effects of Drug Abuse

• No information available

Short-Term Effects

• See "What Are Side Effects Associated with Using Fluocinonide?"

Long-Term Effects

• Chronic topical corticosteroid therapy may interfere with growth and development in children
• Kaposi's sarcoma reported with prolonged corticosteroid therapy
• See "What Are Side Effects Associated with Using Fluocinonide?"

Cautions

• Chronic topical corticosteroid therapy may interfere with growth and development in children
• Use medium to very high potency for less than 2 weeks to reduce local and systemic side effects
• Use low potency for chronic therapy
• Kaposi's sarcoma reported with prolonged corticosteroid therapy
• Avoid medium to very high potency on face, folds, groin because can increase steroid absorption
• If possible, use lower potency for children (increase BSA/kg, therefore increase systemic absorption)
• Children may exhibit greater susceptibility to corticosteroid-induced HPA axis suppression and Cushing's syndrome due to larger skin surface area to body weight ratio

Pregnancy and Lactation

• Use fluocinonide during pregnancy with caution if benefits outweigh risks
• Animal studies show risk and human studies are not available, or neither animal nor human studies were done
• Excretion of fluocinonide into breast milk is unknown, therefore use with caution if breastfeeding
• Consult your treating physician prior to use