Gepirone

Gepirone is pending FDA approval for the treatment of a major depressive disorder.

• Gepirone is available under the following different brand names: Travivo.

Dosages of Gepirone:

Dosage Forms and Strengths

• The average dosage of gepirone used in one study was around 40 mg and it appeared to be favorably tolerated by users.

Dosage Considerations – Should be Given as Follows:

• Effective doses of about 0.01 to 40 mg/kg body weight are contemplated. For certain central nervous system disorders, 15 to 90 mg/day, preferably 30-60 mg/day, are recommended.
• One trial showed that a low dose (10 to 45 mg/day) of gepirone can alleviate symptoms of generalized anxiety within 6 weeks of treatment onset. It is unknown as to whether larger doses (e.g. 40 to 80 mg/day) would result in a quicker onset of gepirone’s action.

Common side effects of gepirone include:

• Diarrhea
• Dizziness
• Headaches
• Insomnia
• Lightheadedness
• Nausea
• Restlessness
• Spinning sensation (vertigo)

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Gepirone is pending FDA approval.

Gepirone may interact with:

• CYP3A4 inducers (e.g. butalbital, carbamazepine, phenobarbital, phenytoin, St. John's wort, etc.)
• CYP3A4 inhibitors (e.g. cobicistat, indinavir, itraconazole, ketoconazole, etc.)
• monoamine oxidase inhibitors (MAOIs)
• other antidepressants

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

Warnings

• This medication contains gepirone. Do not take Travivo if you are allergic to gepirone or any ingredients contained in this drug.

Contraindications

• No information available

Effects of Drug Abuse

• No information available

Short-Term Effects

• See "What Are Side Effects Associated with Using Gepirone?"

Long-Term Effects

• See "What Are Side Effects Associated with Using Gepirone?"

Cautions

• No information available

Pregnancy and Lactation

• Gepirone is pending FDA approval. There is no information available regarding the use of gepirone during pregnancy or while breastfeeding. Consult your doctor.