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Horse Chestnut Seed: Side Effects, Uses, Dosage, Interactions, Warnings

Horse Chestnut Seed

What Is Horse Chestnut Seed and How Does It Work?

Horse Chestnut Seed is a herbal supplement used for the treatment of diarrhea, fever, varicose veins, hemorrhoids, and enlarged prostate.

  • Horse Chestnut Seed is available under the following different brand names: aescin, Aesculaforce, aesculus hippocastanum, chestnut, de marronier d'Inde, eschilo, escine, graine de marronier d'Inde, HCSE, hippocastani semen, marron europeen, marronier, rosskastanie, Spanish chestnut, venastat, venostat, venostatin, Venostasin

What Are Side Effects Associated with Using Horse Chestnut Seed?

Common side effects of Horse Chestnut Seed include:

  • upset stomach.
  • headache, dizziness; or
  • itching

Serious side effects of Horse Chestnut Seed include:

  • severe skin redness, 
  • swelling, 
  • itching, or rash.

Rare side effects of Horse Chestnut Seed include:

  • none 

Seek medical care or call 911 at once if you have the following serious side effects:

  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out.
This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

What Are the Dosages of Horse Chestnut Seed?

Suggested Dosing

Seed Extract

  • 250-750 mg/d orally in divided doses
  • Tincture
  • 1-4 ml orally three times a day

Other Information

  • Extract standardized to 20-22% saponins

Dosage Considerations – Should be Given as Follows

  • See “Dosages”

What Other Drugs Interact with Horse Chestnut Seed?

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first

  • Horse Chestnut Seed has severe interactions with no other drugs.
  • Horse Chestnut Seed has serious interactions with no other drugs.
  • Horse Chestnut Seed has moderate interactions with at least 69 other drugs.
  • Horse Chestnut Seed has minor interactions with at least 35 other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all your products. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your healthcare professional or doctor for additional medical advice, or if you have health questions or concerns.

What Are Warnings and Precautions for Horse Chestnut Seed?

Contraindications

  • Hepatitic impairment, infectious GI conditions, inflammatory GI conditions, renal impairment

Effects of drug abuse

  • None

Short-Term Effects

  • See “What Are Side Effects Associated with Using Horse Chestnut Seed?”

Long-Term Effects

  • See “What Are Side Effects Associated with Using Horse Chestnut Seed?”

Cautions

  • Bleeding disorders, concurrent hypoglycemic agents, diabetes mellitus
  • WARNING: use only standardized seed extract; raw seed, leaf, bark, or flower is possibly fatal

Pregnancy and Lactation

  • raw seed unsafe; avoid use

Lactation

  • avoid use
References
https://reference.medscape.com/drug/aescin-aesculaforce-horse-chestnut-seed-344492#0