How Do Antiviral Endonuclease Inhibitors Work?

Antiviral endonuclease inhibitors inhibit the cap-dependent endonuclease present in the influenza virus. The cap-dependent endonuclease is an enzyme essential for the initiation of viral replication. Thus, by inhibiting cap-dependent endonuclease, viral replication is prevented, which reduces the viral load and influenza infection.

Antiviral endonuclease inhibitors are used for treating influenza infection.

Some of the side effects of antiviral endonuclease inhibitors include:

• Diarrhea/bloody diarrhea
• Nausea
• Headache
• Swelling of the face, eyelids, and tongue 
• Dysphonia, angioedema, anaphylactic reactions
• Rash and itching
• Vomiting
• Hallucinations
• Confusion

The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

Generic and brand names of antiviral endonuclease inhibitors include:

• Baloxavir marboxil
• Xofluza