HOW DO CHOLINERGIC TOXICITY ANTIDOTES WORK?
Cholinergic toxicity antidotes are used to treat cholinergic toxicity that may be caused because of insecticides, nerve agents, medications, and mushrooms.
Cholinergic toxicity may result from drugs or substances that mimic or enhance the action of the neurohormone acetylcholine. Acetylcholine is an important neurohormone in the parasympathetic nervous system responsible for muscle contractions and secretions from the gland. Cholinergic toxicity occurs due to the excess acetylcholine present in the body leading to:
- Vomiting
- Abdominal cramping
- Decreased heart rate
- Paralysis
- Confusion
- Headache
- Drowsiness
- Bronchoconstriction (narrowing of the airways of the lung)
Cholinergic toxicity antidotes compete with acetylcholine and inhibit its action, thereby reversing the cholinergic toxicity.
HOW ARE CHOLINERGIC TOXICITY ANTIDOTES USED?
Cholinergic toxicity antidotes are used to treat:
- Organophosphates and carbamates insecticide poisoning
- Bronchospasm
- Sinus bradycardia (slow heartbeat)
WHAT ARE SIDE EFFECTS OF CHOLINERGIC TOXICITY ANTIDOTES?
Cholinergic toxicity antidotes can cause the following side effects:
- Blurred vision
- Dizziness
- Pain at the injection site
- Double vision
- Headache
- Seizure
- Drowsiness
- Nausea
- Cardiac arrest
- Dry eyes
- Rash
- Dry skin
- Increased blood pressure
- Decreased renal function
- Muscular weakness
The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.
