Hydroxyamphetamine-Tropicamide

Hydroxyamphetamine-Tropicamide is a topical mydriatic used for pupil dilation (mydriasis) in routine diagnostic procedures and in conditions where short-term pupil dilation is desired.

• Hydroxyamphetamine-Tropicamide is available under the following different brand names: Paremyd

Common side effects of Hydroxyamphetamine-Tropicamide include:

• increased intraocular (eye) pressure
• stinging
• dryness of the mouth
• blurred vision
• sensitivity to light
• slow heart rate
• headache
• allergic reactions
• nausea
• vomiting
• pale skin (pallor)
• muscle rigidity
• central nervous system disturbances
• behavioral disturbances.

Serious side effects of Hydroxyamphetamine-Tropicamide include:

• death owing to myocardial infarction
• ventricular fibrillation
• significant hypotensive episodes

Rare side effects of Hydroxyamphetamine-Tropicamide include:

• none 

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Adult dosage

Ophthalmic solution

• 1%/0.25%

Mydriasis/Cycloplegia

Adult dosage

• Dose: One to two drops in the conjunctival sac

Dosage Considerations – Should be Given as Follows:

• See "Dosages"

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, healthcare provider, or pharmacist first

• Hydroxyamphetamine-Tropicamide has no noted severe interactions with any other drugs
• Hydroxyamphetamine-Tropicamide has no noted serious interactions with any other drugs
• Hydroxyamphetamine-Tropicamide has no noted moderate interactions with any other drugs
• Hydroxyamphetamine-Tropicamide has no noted minor interactions with any other drugs

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all your products. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your healthcare professional or doctor for additional medical advice, or if you have health questions or concerns.

Contraindications

• Hypersensitivity to product components
• Known or suspected angle-closure glaucoma, presence of a shallow anterior chamber unless gonioscopic observation of the chamber angle is possible; the presence of narrow-angle where pupil dilation may precipitate angle-closure glaucoma

Effects of drug abuse

• None

Short-Term Effects

• See "What Are Side Effects Associated with Using Hydroxyamphetamine-Tropicamide?"

Long-Term Effects

• See "What Are Side Effects Associated with Using Hydroxyamphetamine-Tropicamide?"

Cautions

• Monitor patients with cardiac disorders, diabetes mellitus, hypertension, or hyperthyroidism
• May cause increased intraocular pressure (use with caution in patients with glaucoma)
• Possibility of undiagnosed glaucoma should be considered
• The elderly may experience intraocular pressure increase following use; use caution

Pregnancy and Lactation

• Use with caution if the benefits outweigh the risks during pregnancy
• Lactation
  • Unknown if excreted in breast milk; use caution