Iodoquinol

Iodoquinol is a prescription medication used to treat the symptoms of an intestinal infection called amebiasis 

• Iodoquinol is available under the following different brand names: Yodoxin

Adult dosage

Tablets

• 210 mg
• 650 mg

Intestinal Amebiasis

Adult dosage

• 650 mg orally after meals every 8 hours for 20 days; not to exceed 2 g/day

Pediatric dosage

• 30-40 mg /kg /day divided orally every 8 hours after meals for 20 days; not to exceed 1.95 g/day

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”

Common side effects of Iodoquinol include:

• diarrhea
• nausea or vomiting
• stomach pain
• headache
• itching of the rectal area

Serious side effects of Iodoquinol include:

• blurred vision or any vision change.
• clumsiness or unsteadiness.
• decreased vision or eye pain.
• increased weakness.
• muscle pain.
• numbness, tingling, pain, or weakness in hands or feet.

Rare side effects of Iodoquinol include:

• none

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
• Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; sudden dizziness, lightheartedness, or passing out.

This is not a complete list of side effects and other serious side effects or health problems that may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

• Iodoquinol has severe interactions with no other drugs.
• Iodoquinolhas serious interactions with the following drugs:
  • axicabtagene ciloleucel
  • brexucabtagene autoleucel
  • ciltacabtagene autoleucel
  • idecabtagene vicleucel
  • lisocabtagene maraleucel
  • tisagenlecleucel
• Iodoquinol has no noted moderate interactions with any other drugs.
• Iodoquinol has minor interactions with the following drugs:
  • cadexomer iodine
  • iodinated glycerol
  • iodine

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all your products. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions or concerns.

Contraindications

• Hypersensitivity to 8-hydroxyquinoline or Iodoquinol
• Iodine sensitivity
• Pre-existing optic neuropathy
• Hepatic damage

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Iodoquinol?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Iodoquinol?”

Cautions

• Caution in thyroid disease
• Interferes with thyroid tests for up to 6 months after discontinuation
• Do not repeat the course before 2-3 weeks
• Not effective in amebic hepatitis or liver abscess
• Avoid long-term therapy (associated with optic neuritis and optic atrophy)

Pregnancy and Lactation

• Use with caution if the benefits outweigh the risks during pregnancy.
• Lactation
  • Unknown