How Do Keratinocyte Growth Factors Work?

Keratinocyte growth factors are drugs used for treating severe mouth and throat sores associated with chemotherapy and radiation.

Keratinocyte growth factors stimulate cell growth in the mouth and throat. They also bind to specific receptors present on the surface of cells in the lining of the mouth, stomach, and intestines, thus protecting these cells from the harmful effects of certain chemotherapy.

Keratinocyte growth factors are used for treating severe sores in the mouth and throat caused by chemotherapy or radiation that is directed against blood or bone marrow cancers.

Some of the side effects of keratinocyte growth factors include:

• Rash
• Fever
• Itching
• Redness
• Swelling
• Pain
• Discoloration of the mouth or tongue
• Altered taste
• Joint pain
• Cough
• Vaginal redness
• Vaginal swelling
• Cataract

The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

Generic and brand names of keratinocyte growth factors include:

• Kepivance
• Palifermin