Age 66, had prostate surgery, PSA didn't go down to zero. So given lupron shot preliminary to radiation treatment, also at least 1 more after radiation done. PSA since 2019 zero, but had pretty bad hot flashes day and night for first year or so which were not easy to deal with. Gradually got less severe, gone from day and less at night but still there after 3 years. I hope they go away completely but since this is the only problem I've had since cancer treatments, I don't feel too bad about things.
Lupron depot shot have increased my anxieties and I am having panic attacks regularly. My depression has increased with Tamoxifen and Lupron combination. Oncologist did not tell me this was a side affect when I began treatment. I did tell him I had anxieties and severe depression. Normal coping mechanisms are not working. I have had increased suicidal thoughts. Now I feel like I have to choose between dying because of breast cancer or because of suicidal thoughts. Feel like I'm going crazy.
Young patient. Within the first 4 months, noticed emotional instability, daily hot flashes, discontinuation of menstrual cycle, and a difference in body shape, notably in the hips, chest, and legs. Months 5-8, depressive episodes and ongoing fatigue. Nothing debilitating, but enough to knock even a very optimistic person such as myself to a considerably quieter and antisocial state. Overall, works as advertised and no unexpected side effects have presented.
Kept Psa low. Nine months into quarterly injections, more side effects occured - rash, swelling of ankles, feet, muscle joint and bone pain,. Testicle and penis shrinking in first three months. Slight breast enlargement, weight gain
I can’t deal with all of the symptoms at the same time. It was taking all the good that I put in my body.
Hasn’t been all that bad. I’ve only had a few weeks so far but the experience hasn’t been life changing or anything. I’ve had a few hot flashes and such, and getting an injection so deep in your thigh is never fun, but it’s doing it’s job. Overall it wasn’t as scary as some of these comments make it out to be for me. That may just be because I’m quite young
On Lupron for 2 years. Last injection was 9 months ago. Still having all of the bad side effects. When does this drug wear off?
Worst experience I've had. Gave me hives & water blisters & intense itching all over my body - ears, arms, chest & back, thighs & legs, even my palms & back of hands, top & bottom of feet. It's now 3 months later & still have itching, rashes and scabs & leathery skin. Also still getting hot flashes, shrunken "manhood", slightly enlarged breasts including pain & fluid leaking at the nipples. The fluid dries crusty and is also coming out of every sore & rash area. I refuse to get this poison ever again. My urologist only suggested using Benedryl - which by the way should NOT be used when your prostate is enlarged and blocks urine flow - so there is NO REMEDY to reverse these horrible side effects. The injection I got was a 6 month dose so my hope is within the next 3 months the bad side effects will subside. Just finished 39 sessions of radiation. Oncologist recommended a total of 24 months hormone therapy so this means going back for monthly doses of firmagon for an additional 15 months. Not looking forward to that & may seek other alternatives.
Please note that many of these women are inaccurately reviewing this Lupron Solution when they have actually take Lupron DEPOT, a long-acting whopping dose of the drug. Similar side effects in many cases but they are not reviewing the correct drug.
I have been diagnosed with advanced endometriosis and have been on lupron for over two years. I have suffered severe depression and anxiety along with nightmares and hot flashes. I seriously suggest not taking this medication at all costs. I believe it is very lethal and dangerous.
Has caused my prostate to shrink but has also made me nuts.Brought back unpleasant memories from 50 years ago that I had completley forgotten about and I can't stop thnking about.I have crying spells that last for 15 or 20 minutes almost every day
six month injection for prostate cancer. My reaction has not been good. Lots of bone pain, lower back pain, trouble breathing, enlarged heart, so tired I can hardly get out of bed. The doctor didn't take this part of my health problem: CFS and fibro. I am at the end of the six months and still having all the issues.
Loss of Balance and muscle strength
dont take this poison, it has very bad side effects, and they are permanent, memory loss, fatigue body aches, very high blood pressure ,and a lot more and they are permanent
Prostate removed 2001; Gleason score 7. PSA zero until 2013, when it started to increase. Started quarterly Lupron injections mid-2013. Testosterone and PSA have been zero since then. Fatigue, awakening every 2-3 hrs. at night to urinate and hot flashes are difficult, but overall I consider myself lucky. Daily Vitamin E seems to help hot flashes. Libido and urinary retention were affected by my prostate removal, so are not new issues.
has helped prostate cancer side effects terrible. hives are on going hives since may 30 very debilitating, had them all over body ears eyes mouth. can nonger take for my cancer
I was on Lupron for 6 months 2 years ago. It was wonderful while I was on it, but my endometriosis and fibroid pain were back within 5 months of being off the Lupron. Now, not only do I contend with that pain, but severe joint pain and bone loss, too. All the exercise, diet and supplements have not protected me from what I am going through now.
I am only 1 week into my first shot but so far I have gained 7lbs in a week. My feet are swelling and my "cramps" are worse. So far no good.
I had my prostate and lymph glands removed in 2019 due to prostate cancer. PSA levels were undetectable at < 0.008 until my 3 year checkup in 2022. PSA levels were at 0.06 and went up over the next several months. Started 2 months of external radiation treatment in at the start of 2023 combined with 2 years of ADT. Began ADT in December of 2022 with casodex and another monthly anti-androgen. I had severe hot flashes on the first shot. Oncologist switched me to 6 month Lupron injections. I have just had my 3rd 6 month shot, so I am into my last year of this stuff. It is horrible. I have had frequent hot flashes like everyone else. That is tolerable. I have had progressing joint and bone pain, fatigue, loss of muscle mass, weight gain even though I mostly eat only 1 meal a day, complete loss of sexual function and desire, any penis length that remained after the surgery was completely gone. I have extreme depression and anxiety for which I am in treatment. The worst is the brain fog. I have such a hard time concentrating and remembering things. My ability to stay on task has dropped to zero. Each time I have received my shot, the immediate pain side effects has increased both in intensity and duration. I am 2 weeks since my 3rd injection and just now to the point that I can bend my back and feel some relief from my pain medication. Definitely plan on being on lots of pain medication with lupron. Yes, I will finish out my 2 years of treatment. It has kept my PSA levels undetectable which is supposed to mean that it is working and killing any remaining cancer cells that slipped by the radiation treatments (which also have a list of side effects). If I start to test positive after completion of two years of treatment, would I consider chemotherapy and more lupron? I think I may look for alternatives, even if it is just lots of pain meds and weed. I think I would rather go out feeling good than enduring this again.