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Fetzima Drug and Medication User Reviews on RxList

Fetzima

USER REVIEWS

Comment from: Fetzima sucks 45-54 Transgender less than 1 month Caregiver Published: February 13

Horrible medicine....pls stay away. Started taking 80MG since other medicines had stopped working (Pristiq, Wellbutrin). Only could take 4 pills over 4 days - terrible nausea, constipation and trouble urinating within a few hours of taking the 1st pill......chills, headaches on top of it.....vomited multiple times over th3 4 days. Now advised to stop taking it immediately. Spent over $300 for a 30 day supply (since it brand name - not covered by insurance), used only 4 pills and wasted my money....Lesson learnt.....worst medicine ever.

Comment from: MD 45-54 Transgender 1 to 6 months Caregiver Published: January 11

I've dealt with MDD since I was in my teens. Have tried multiple medications and they seem to stop working after awhile. Fetzima is similar in this regard. It worked for awhile and seems like my depression symptoms have gotten worse in the past month or so. I've tried a few of the newer anti-depressants (Caplyta, quetiapine, vilazodone, Pristiq) and they made me very irritable and weird feeling. The only anti-depressant that really worked for me (and then I maxed out the dosage) was Cymbalta. I'm currently taking Auvelity with the Fetzima and it doesn't seem to have any effect. I have not stopped taking the Auvelity so maybe it does.

Comment from: Dee 45-54 Transgender less than 1 month Caregiver Published: October 26

Just started taking this medication and if I take it in the morning I seam to be angry so I started taking it at night along with abilify. I tried at least 13 different medications and Trintellix was wonderful but got sick every day. I always have high hopes but only time will tell. Wishing for the best.

Comment from: Gmall 55-64 Transgender 5 to less than 10 years Caregiver Published: July 23

I have had no side effects at any time while taking Fetzima

Comment from: Lea82 25-34 Transgender 1 to 6 months Caregiver Published: September 17

My main diagnosis is MDD, GAD, OCD, Social Anxiety and possibly bipolar 2(not determined). I had a 14 year love/hate affair with Effexor which helped me with certain things but destroyed my life in other ways, we won’t go there now. I then switched to Zoloft and I did not like how I felt on it. After 1 year on it I switched to Cipralex 20mg and that seemed to be the best fit. My depression was under control but my anxiety was not. I was calm and my sleep was good, too good. I was oversleeping, napping and felt sluggish overall. My doctor added 10mg-30mg of adderall which was a wonderful combination in addition to the cipralex but after a while I did not do too well with the “crashes” and instability that adderall caused. I did my research and in July of 2022 I switched to Fetzima as it was more energizing and motivating. I started with 20mg, 40mg, 60mg up to a max of 80mg in 5 weeks. It’s now September of 2022 and I must say that overall it has not been a good experience. My energy and focus are better but this is pointless because my depression is much worse. I’ve had crying spells and days that I didn’t want to get out of bed. My anxiety has been TERRIBLE. I go to bed bombarded by overwhelming thoughts and worries just to wake up in the morning by the same tormenting thoughts. Also i cannot seem to fall asleep. I end up falling asleep around 5 am and waking up at 8am. I feel nervous, worried, mentally and physically anxious and my heart rate is very high. I feel overall uncomfortable, as if I’m not taking anything. I don’t think this medication is working for me and if it is it’s working in the wrong way. Ready to leave it asap and try something else. Not living like this.

Comment from: Amybee 55-64 Transgender 1 to less than 2 years Caregiver Published: June 09

Fetzima seemed to work for awhile, but the side effects have been horrible. My heart has been beating rapidly and I sweat profusely every day. I did think it was helping my mood for awhile but no longer is. In fact, I think it is now making me depressed. I feel so low and hopeless. I have started to wean off of Fetzima; can’t wait to be off completely.

Comment from: Mike 35-44 Transgender Caregiver Published: February 24

Took on a new roll as a manager January of 2021 had a massive panic attack in October of 2021 due to stress I guess? never had one before I even called 911 as I thought I was having a Heart attack! since then i have had anxiety and panic attacks. my Dr started me on Trintrellx which made me feel light headed and dizzy. then she tried me on Zoloft and that was awful, didn't want to eat felt like nothing mattered and did not want to do anything. so she tried me on this at 20mg a day and so far it seems to be working as before the only thing that would work was lorazepam. fingers crossed and I'll report aging after the 2 weeks are in. stay safe and there is always someone to talk to.

Comment from: Melinda E. 45-54 Female less than 1 month Patient Published: February 06

I have only been taking Fetzima for a very short time and I already feel like my old self from many yrs ago. I am eager to get up and start my day. I set goals that I can accomplish. I have so much energy! I never thought life could be this great for me again. I suffer from MDD. The only thoughts I had all day everyday was wanting to die. For me this is a miracle drug. If you suffer from MDD, I strongly recommend that you talk to your Dr about this medication. I don't have any side effects other than dry mouth but I have had it with other medications that I take. You deserve to live a fullfilled life. Best of luck and prayers your way.

Comment from: funnygirlm 45-54 Female 2 to less than 5 years Patient Published: February 12

I have been on Fetzima for 4 years to date. I started with the starter pack and was increased to 40mg almost immediately. It worked for me within 2 weeks and this lasted for a good year. Then, the usual, no longer really working so my doctor and I agreed to 60mgs (yes I know it doesn't come in this dosage- one 40mg and one 20 mg daily). Again this mg worked for almost 2 years before I need to again raise the mg to 80 mg daily. This is where I am currently and I am doing okay. Not as good as I was but managing. I will most likely end up increasing my dose to 100 before the year is over. I chose to go up by 20 so I could get by on the lowest dose to hopefully prolong my use as changing antidepressants is unpleasant at best and suicidal at worst. I have had MDD for the majority of my life. I have taken zoloft, Wellbutrin, Prozac, and Paxil in the past. Zoloft worked for about 8 months then nothing. Welbutrin made me ill with flu-like symptoms. Prozac made me very aggressive and angry and Paxil made me sick to my stomach and emotionally fragile. I would love to think I could get 10 years out of this drug, but I do not have high hopes. It has worked better than any other med for me. It changed my outlook on life in less than 2 weeks.

Comment from: Amybee 45-54 Female 1 to 6 months Patient Published: October 03

This was added to other medications I take for depression/being on the bipolar spectrum. More than anything else, it has improved my energy level, which tends to be low due to depression. I am taking 40 mg but would like to see if I notice increased improvement at 80 mg or higher.

Comment from: CC 35-44 Female 2 to less than 5 years Patient Published: April 04

I've tried most antidepressants on the market to treat my MDD over the last almost 20 years and none have ever really helped. My doctor prescribed Fetzima to use in combination with Wellbutrin and honestly, I've never felt better. These drugs, along with a great therapist, saved my life. I've been taking it steadily for about 3-4 years and feel great. The only side effect I've noticed is dry mouth. Overall, I'm very pleased with it and hope a generic version comes soon.

Comment from: Debie 45-54 Female Patient Published: January 27

I have been on med for about 2 months. Using it for fibromyalgia brain fog and fatigue. It seems to be working. I have just increased dose to 80 mg. Will see how that works out.

Comment from: 45-54 Female 1 to 6 months Patient Published: November 03

I tool this med for about 2 months. I could not sleep or eat on this medication. I also was extremely angry and had worse anxiety than before starting! I work in pharmacy and know that side effects will usually subside and that is the only reason I stayed it as long as I did. Then I changed jobs, so had a lapse in insurance, when I called about a cash price it was $400. My Dr did not have samples, so I ran out. The withdrawal from this med made me think I was losing my mind! I had my friend hide my gun, because I was afraid I might get to a point where I would hurt my self or another! I have NEVER felt so out of control in my 48 years! How I kept my new job, is nothing short of a miracle. It took about 4-6 weeks to get back to normal. I am back on Prozac and feel better than I have in a long time!

Comment from: Believeinyourself 25-34 Female less than 1 month Patient Published: April 20

I'm 29 female 5 foot 8 and 180lbs solid build with some weight on my mid section The upbeat mood was fantastic but however devastating. I'm on lamotrigine and as unsure as it could be my own reaction. I suffered some horrible symptoms for 3 weeks - Several migraines that lasted for literally 2 weeks straight - Eye pain (I do have glaucoma) - Upset stomach - Once vomited - After coming off I had sever violent mood swings leading to outbursts - Neck pain back pain which on week 4 has not gone away yet -Muscle pain -Muscle flinching as if my brain was getting electro shocked and I could feel it in my body -Sever confusion to the point I couldn't tell what happened and didn't really happen example I thought people said things about me and it seemed real until I realized nothing actually happened this terrified me -Weakness to the point i could hardly get up -Sever chest pain -Always out of breath -Sore nose as if stinging -Blurry eyes -Watery and burning eyes -Broken sleep -Thoughts of losing sanity -Thoughts of suicide and it has been 4 years since the last thought -Weight gain -Out of control hunger -Chills -Sweats -Shaking -Shivering -Difficulty warming up VERY IMPORTANT what hurt the most I couldn't hold my 2 year old or even give her a kiss as I noticed she was showing signs from skin contact. (Could be related to sweating to) This was only 2 weeks and unfortunately at week 4 of writing this im only now starting to feel better. I do warn people dont mix the two unfortunately they do react but again there is only a chance. I was so excited that it worked to a fairly good degree by week 2 but the reaction after the rash was an emergency to stop. I actually sobbed i was so devestated i had to stop. My doctor has tried so hard and we both thought this would work. I trust his judgement and hopefully maybe fetzima can work more on it to minimize the reactions it could be wonderful but it just needs some more work

Comment from: TL3180 55-64 Female less than 1 month Patient Published: June 25

I've been taking 40 mg Lexapro for the last 15 years with decreased efficiency in the last 6 mos. My doctor started me on Fetzima 2 weeks ago; 1st 2 days at 20mg and the last 12 days at 40mg. The last 2 days I've noticed extreme agitation to the dismay of my daughter. However I have also noticed I am less lethargic, less appetite (both desirable) mood and concentration has improved. I start on 80mg beginning tomorrow. Hoping the agitation goes away and this medication will be the one that gives me a better quality of life.

Comment from: Alliekona 45-54 Female 1 to less than 2 years Patient Published: September 30

After being on several different types of anti-depressants over 20 years off and on, I finally feel like I found a RX that works. Fetzima was a game changer for me, 80mg taken in the AM. I also suffer from ADD, and unfortunately I accidentally weaned myself and as a result suffered severe migraines. Been completely off now for about a month and will be meeting with my doctor soon to discuss what's next. Honestly, I feel more "normal" now than ever and I think it's because of taking Fetzima for the last 15 months. I'm not inclined to go back on it, now, but if in the future I find myself chronically depressed again, this will be my go to anti-depressant. This RX was recommended after taking a "GeneSight" test that informed my doctors and myself of what types of medicines would be most effective for me based on MY genes/DNA. I highly recommend everyone take this simple saliva test. It's worth every dollar!

Comment from: Bash99 45-54 Male less than 1 month Patient Published: September 27

This medication has helped me with my depression. I have more energy and focus, and my mood is improved. I'm able to sleep just fine on this medication. No negative side effects so far. I'm on 40 mg and may increase to 80 mg in preparation for my seasonal variation to my mood.

QUESTION

Depression is a(n) __________ . See Answer
Comment from: 45-54 Female 1 to 6 months Patient Published: August 20

I'm on 120mg.. have had stomach pains, crying more, anxiety is worse, feeling worse, can't get out of bed, feeling blue, loss of appetite.

Comment from: nofetzima 65-74 Female 1 to less than 2 years Patient Published: August 12

1 month after starting before minimal improvement. during 1 year taking fetzima NEVER achieved 1)relief of anxiety, 2)ability to multi task, 3} ease to complete projects, 4) sleep improvement

Comment from: Need hope 45-54 Female 1 to 6 months Patient Published: August 03

Anxiety is terrible on this drug, panic attacks, afraid to be alone, heart beats fast, chest pain, constantly crying, shaking, I worry about everything, Constipation, appetite decrease, I think I am having a nervous break down. Feel hopeless

References
Medical Editor: John P. Cunha, DO, FACOEP