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Lidocaine Transdermal: Side Effects, Uses, Dosage, Interactions, Warnings

Lidocaine Transdermal

What Is Lidocaine Transdermal and How Does It Work?

Lidocaine Transdermal is a prescription or over-the-counter medication used for relieving temporary pain and pain associated with postherpetic neuralgia.

  • Lidocaine Transdermal is available under the following different brand names: Lidoderm, Ztlido, Lidocare Patch

What Are Dosages of Lidocaine Transdermal?

Adult and pediatric dosage

Transdermal patch

  • 5%; 700mg/patch (Lidoderm; Rx)
  • 1.8%; 36mg/patch (ZTlido; Rx)
  • 4% (Lidocare Patch; OTC)

Postherpetic Neuralgia Pain

Adult dosage

  • Lidoderm 5% Transdermal patch: Apply to intact skin to cover the most painful area
  • Apply up to 3 patches, only once for up to 12 hours within 24 hours

Temporary Pain Relief

Adult and pediatric dosage

  • Lidocare 4% Transdermal patch: Apply patch to the affected area every 8-12 hours or as needed
  • May leave patch on the skin for up to 8, but no more than 12 hours

Dosage Considerations – Should be Given as Follows: 

  • See “Dosages”

What Are Side Effects Associated with Using Lidocaine Transdermal?

Common side effects of Lidocaine Transdermal include:

  • mild irritation where the medication is applied, and
  • numbness in places where the medicine is accidentally applied.

Serious side effects of Lidocaine Transdermal include:

  • severe burning,
  • stinging,
  • irritation at the application site,
  • swelling or redness,
  • sudden dizziness or drowsiness after application,
  • confusion,
  • blurred vision,
  • ringing in the ears, and
  • unusual sensations of temperature.

Rare side effects of Lidocaine Transdermal include:

  • none 

This is not a complete list of side effects and other serious side effects or health problems that may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

What Other Drugs Interact with Lidocaine Transdermal?

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

  • Lidocaine Transdermal has no noted severe interactions with any other drugs.
  • Lidocaine Transdermal has no noted serious interactions with any other drugs.
  • Lidocaine Transdermal has no noted moderate interactions with any other drugs.
  • Lidocaine Transdermal has no noted minor interactions with any other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all the products you use. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions or concerns.

What Are Warnings and Precautions for Lidocaine Transdermal?

Contraindications

  • Known history of sensitivity to local anesthetics of the amide-type, or to any other component of the product

Effects of drug abuse

  • None

Short-Term Effects

  • See “What Are Side Effects Associated with Using Lidocaine Transdermal?”

Long-Term Effects

  • See “What Are Side Effects Associated with Using Lidocaine Transdermal?”

Cautions

  • Patients allergic to para-aminobenzoic acid (PABA) derivatives (e.g., procaine, tetracaine, benzocaine) have not shown cross-sensitivity to lidocaine; however, be aware of the potential for cross-sensitivity in patients allergic to PABA derivatives, especially if the etiologic agent is uncertain
  • If irritation or a burning sensation occurs during application, advise patients to remove the patch and do not reapply until the irritation subsides
  • When used concomitantly with other products containing local anesthetic agents, the amount of lidocaine absorbed from all formulations must be considered
  • Dispose of used lidocaine patches properly to avoid toxicity in small children or pets; used lidocaine patches contain a large amount of lidocaine
  • Application to broken or inflamed skin, although not tested, may result in higher blood concentrations of lidocaine from increased absorption; apply only to intact skin
  • External heat sources (e.g., heating pads, electric blanket), longer duration of application, application of more than recommended number of patches, smaller patients, impaired elimination may contribute to increasing systemic absorption from Transdermal patch; advise patients of proper application and duration
  • Severe hepatic impairment may decrease systemic elimination of lidocaine
  • If eye contact occurs, immediately wash out the eye with water or saline and protect the eye until sensation returns

Pregnancy and Lactation

  • There are no available data regarding use in pregnant women
  • Reproduction studies with lidocaine have been performed in rats at doses up to 30 mg/kg SC and have revealed no evidence of harm to the fetus due to lidocaine
  • There are, however, no adequate and well-controlled studies on pregnant women
  • Because animal reproduction studies are not always predictive of human response, should be used during pregnancy only if needed
  • Lactation
    • There are no available data regarding use in breastfeeding women; caution if administered
    • Lidocaine is excreted in human milk, and the milk: plasma ratio of lidocaine is 0.4
References
Medscape. Lidocaine Transdermal.

https://reference.medscape.com/drug/lidoderm-ztlido-lidocaine-Transdermal-1000223#6