Loratadine-Pseudoephedrine

Loratadine-Pseudoephedrine are a combination over-the-counter medications used for relieving nasal congestion.

• Loratadine-Pseudoephedrine are available under various brand names: Alavert D-12, Allergy & Congestion Relief, Allergy Relief & Nasal Decongestant, Allergy Relief-D 24 Hour, Claritin-D 12 Hour, Claritin-D 24 Hour, Clear-Atadine-D, Leader Allergy Relief D-24, Loratadine-D 12 Hour, Loratadine-D 24 Hour, Wal-itin D, Wal-itin D 24 Hour

Common side effects of Loratadine-Pseudoephedrine include:

• dry mouth, nose, or throat;
• mild dizziness; or
• sleep problems (insomnia).

Serious side effects of Loratadine-Pseudoephedrine include:

• hives,
• difficulty breathing,
• swelling of the face, lips, tongue, or throat,
• pounding heartbeats or fluttering in your chest; or
• severe dizziness, nervousness, or restless feeling.

Rare side effects of Loratadine-Pseudoephedrine include:

• none

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheartedness, or passing out.

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Adult and pediatric dosage

Tablet, extended-release

• 5 mg/120 mg
• 10 mg/240 mg

Cold, allergy symptoms

Adult dosage

• Loratadine 5 mg/pseudoephedrine 120 mg per tablet: One tablet every 12 hours (maximum: 2 tablets/day)
• Loratadine 10 mg/pseudoephedrine 240 mg per tablet: One tablet daily (maximum: 1 tablet/day)
• Seasonal allergic rhinitis/nasal decongestion

Pediatric dosage

• Children above 12 years and Adolescents:
• 12-hour formulation (loratadine 5 mg and pseudoephedrine 120 mg/tablet): Oral: 1 tablet every 12 hours.
• 24-hour formulation (loratadine 10 mg and pseudoephedrine 240 mg/tablet): Oral: 1 tablet once daily.

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

• Loratadine-Pseudoephedrine have severe interactions with the following drugs:
  • dihydroergotamine
  • dihydroergotamine inhaled
  • dihydroergotamine intranasal
  • ergoloid mesylates
  • ergonovine
  • ergotamine
  • isocarboxazid
  • linezolid
  • mavacamten
  • methylergonovine
• Loratadine-Pseudoephedrine have serious interactions with at least 42 other drugs.
• Loratadine-Pseudoephedrine have moderate interactions with at least 204 other drugs.
• Loratadine-Pseudoephedrine have minor interactions with at least 13 other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all your products. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions or concerns.

Contraindications

• Documented hypersensitivity to drugs or excipients
• Severe hypertension or coronary disease
• Concurrent or within 14 days of MAO inhibitor use.

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Loratadine-Pseudoephedrine?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Loratadine-Pseudoephedrine?”

Cautions

• This medicine may cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you.
• Drinking alcohol can increase certain side effects of this medication.
• Ask a doctor or pharmacist before using other cough or cold medicines that may contain similar ingredients.
• Do not use birth control pills if you are pregnant or if you have recently had a baby.
• Using Loratadine-Pseudoephedrine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
• Do not use Loratadine-Pseudoephedrine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Pregnancy & Lactation

• Do not use this medicine without a doctor's advice if you are pregnant.
• Lactation
  • You should not breastfeed while using this medicine.