Magaldrate

Magaldrate is used to treat heartburn, sour stomach, acid indigestion, hyperphosphatemia, and magnesium deficiency. Magaldrate is used off-label to treat gastric and duodenal ulcers and gastroesophageal reflux disease (GERD).

• Magaldrate is discontinued.
• Magaldrate is available under the following different brand names: Riopan.

Dosages of Magaldrate:

Dosage Forms and Strengths

Oral Suspension

• 540mg/5mL

Oral Suspension: Magaldrate-Simethicone

• 540mg - 40mg/5mL

Dosage Considerations – Should be Given as Follows:

Heartburn, Sour Stomach, and Acid Indigestion

• 5-10 mL (1-2 teaspoonfuls; 540-1080 mg) between meals and at bedtime; not to exceed 80 mL (16 teaspoonfuls) in 24-hour period

Other Indications and Uses

• Hyperphosphatemia, magnesium deficiency
• Off-label: Gastric and duodenal ulcer, GERD
• Neutralizes gastric acid, increases gastric pH

Safety and efficacy not established in pediatric patients

Common side effects of magaldrate include:

Aluminum oxide

• Chalky taste
• Constipation
• Fecal impaction
• Stomach cramps

Other side effects of magaldrate include:

Aluminum oxide

• Nausea
• Vomiting
• Aluminum intoxication
• Low blood phosphates (hypophosphatemia)
• Bone softening (osteomalacia)

Magnesium oxide

• Diarrhea
• High blood magnesium (hypermagnesemia)

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

• Magaldrate has no listed severe interactions with other drugs.
• Magaldrate has no listed serious interactions with other drugs.
• Magaldrate has no listed moderate interactions with other drugs.
• Magaldrate has no listed mild interactions with other drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

Warnings

This medication contains magaldrate. Do not take Riopan if you are allergic to magaldrate or any ingredients contained in this drug.

Contraindications

• Hypersensitivity to any component

Effects of Drug Abuse

• No information available

Short-Term Effects

• See "What Are Side Effects Associated with Using Magaldrate?"

Long-Term Effects

• See "What Are Side Effects Associated with Using Magaldrate?"

Cautions

• Renal failure, magnesium-restricted diet
• May increase or decrease rate and/or degree of absorption of concomitantly administered oral drugs by changing gastrointestinal (GI) transit time or by binding the drug

Pregnancy and Lactation

• Use magaldrate with caution during pregnancy if the benefits outweigh the risks. Animal studies show risk and human studies are not available or neither animal nor human studies were done.
• It is not known whether magaldrate is excreted in breast milk. Use caution while breastfeeding.