Natamycin Ophthalmic

Natamycin Ophthalmic is a prescription medication used for the treatment of fungal keratitis and fungal blepharitis/conjunctivitis. 

• Natamycin Ophthalmic is available under the following different brand names: Natacyn.

Common side effects of Natamycin Ophthalmic include:

• Tearing,
• Watery eyes, and
• Feeling like something is in the eye.

Serious side effects of Natamycin Ophthalmic include:

• Hives,
• Difficulty breathing,
• Swelling of the face, lips, tongue, or throat,
• Vision changes,
• Eye redness or irritation,
• Swelling of the eye,
• Eye pain or numbness, and
• Chest pain

Rare side effects of Natamycin Ophthalmic include:

• None 

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out. 

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Adult dosage

Ophthalmic suspension

• 5%

Fungal Keratitis

Adult dosage

• 1 drop in conjunctival sac every 1-2 hours
• May decrease to 1 drop 6-8 times/day after 3-4 days.
• Continue for 14-21 days until the infection is eradicated.

Fungal Blepharitis/Conjunctivitis

Adult dosage

• 1 drop in a conjunctival sac 4-6 times/day

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

• Natamycin Ophthalmic has no noted severe interactions with any other drugs.
• Natamycin Ophthalmic has no noted serious interactions with any other drugs.
• Natamycin Ophthalmic has no noted moderate interactions with any other drugs.
• Natamycin Ophthalmic has no noted minor interactions with any other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all your products. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your healthcare professional or doctor for additional medical advice or health questions or concerns.

Contraindications

• Hypersensitivity
• Concurrent use with topical corticosteroid

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Natamycin Ophthalmic?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Natamycin Ophthalmic?”

Cautions

• For keratitis, consider alternative Transmit if no improvement in 7-10 days.

Pregnancy and Lactation

• Use with caution if the benefits outweigh the risks during pregnancy.
• Lactation
  • No problems were reported.