Neomycin/Polymyxin B/Gramicidin Ophthalmic

Neomycin/polymyxin B/gramicidin ophthalmic is used to treat and prevent ocular (eye) infection and/or inflammation.

Neomycin/polymyxin B/gramicidin ophthalmic is available under the following different brand names: Gramicidin, Neosporin Ophthalmic Solution, and Neocin-PG.

Dosages of Neomycin/Polymyxin B/Gramicidin Ophthalmic:

Dosage Forms and Strengths

Ophthalmic Solution

• (1.75 mg/10,000/0.025 mg)/1mL (10mL)

Dosage Considerations – Should be Given as Follows:

Treatment and Prevention of Ocular Infection and/or Inflammation

• 1-2 drops every 4-6 hours for 7-10 days; if severe 2 drops every 1 hour if necessary

Side effects of neomycin/polymyxin B/gramicidin ophthalmic include:

• Hypersensitivity
• Eye itching, swelling, and redness
• Local transient irritation
• Vesicular and maculopapular dermatitis
• Angioneurotic edema
• Hives

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

• Neomycin/polymyxin B/gramicidin ophthalmic has no listed severe interactions with other drugs.
• Neomycin/polymyxin B/gramicidin ophthalmic has no listed serious interactions with other drugs.
• Neomycin/polymyxin B/gramicidin ophthalmic has no listed moderate interactions with other drugs.
• Neomycin/polymyxin B/gramicidin ophthalmic has no listed mild interactions with other drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

Warnings

• This medication contains neomycin/polymyxin B/gramicidin ophthalmic. Do not take Gramicidin, Neosporin Ophthalmic Solution, or Neocin-PG if you are allergic to neomycin/polymyxin B/gramicidin ophthalmic or any ingredients contained in this drug.
• Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

Contraindications

• Aminoglycoside/neomycin hypersensitivity; hypersensitivity to any product component

Effects of Drug Abuse

• No information available

Short-Term Effects

• See "What Are Side Effects Associated with Using Neomycin/Polymyxin B/Gramicidin Ophthalmic?”

Long-Term Effects

• See "What Are Side Effects Associated with Using Neomycin/Polymyxin B/Gramicidin Ophthalmic?”

Cautions

• Watch for neomycin ocular sensitivity
• Defects in visual acuity may occur with prolonged use
• Posterior sub papular cataract formation, and secondary ocular infections were reported with prolonged use

Pregnancy and Lactation

• Use neomycin/polymyxin B/gramicidin ophthalmic with caution during pregnancy if the benefits outweigh the risks. Animal studies show risk and human studies are not available or neither animal nor human studies were done.
• It is unknown if neomycin/polymyxin B/gramicidin ophthalmic is excreted in breast milk. Use caution while breastfeeding.