Literally saved my life. I tried over a dozen other antidepressants first and none of them worked until this one. I did have a stroke several months after starting to take Nardell, although it is very unlikely to be related.
Drastically changed my life for the better. Only medication to work after trying six different ssri's.
Severe social anxiety and treatment-resistant depression had become constant companions in my life, overshadowing any sense of joy or fulfillment. Despite years of trying different medications and therapies, I felt like I was stuck in a never-ending cycle of despair. That was until I discovered Nardil. From the moment I started taking it, I noticed a significant shift in my social anxiety. The racing thoughts and paralyzing fear began to subside, allowing me to engage in social situations with greater confidence and ease. Nardil gave me the ability to navigate social interactions without the constant worry of being judged or rejected. In addition to its impact on social anxiety, Nardil also proved to be a game-changer in my battle against treatment-resistant depression. It lifted the heavy fog of sadness and despair, replacing it with a renewed sense of hope and optimism. Nardil has truly been a lifeline for me, offering a path towards healing and a brighter future."
Gave me lots of side effects with no relief from depression and only a slight decrease in anxiety. Gave it 2 months. When I went to 45mg I was constantly dizzy, couldn't stop crying, almost fainting. If you are sensitive to meds this one is probably not for you.
I was having severe anxiety and at times suicidal impulses- After taking Nardil for several weeks I began to feel euphoric and very energized- IE I became manic and very hard to be around with friends and family- I did not realize that I was manic- I began to shop non-stop- One night I suddently felt despondent and suicidal- In retrospect, the Nardil made me suicidal- I also gained a lot of weight- When finally I was taken off the Nardil I lost the weight and stopped the manic shopping- I also stopped having the euphoric feeling that I could do anything in the world- In the long run, I did much better with SSRIs- The one positive thing about Nardil was that I came to understand how it feels to be manic- As I am a Mental Health Professional this has been useful-
This medication is a life saver. Been on it over 30 years. Have stopped it a couple of times to try “NEWER” drugs…….LORD THAT WAS A MISTAKE!!!! Had to go right back to the one that works, NARDIL!! It has saved my life. I am a longtime nurse and understand about how meds work. Diet is easy if the patient is trustworthy and just needs to be sure they understand med contraindications and the meds they can and cannot take. It is very easy to take and certainly worth following a few rules to have a happy non-depressed.. ……it is sooooooooooooo worth taking this med. I think most Psy mds should consider using on more treatment resistant patients. I am SO THANKFUL FOR THIS MEDICATION. my depression is disabling, on Nardil, I am super NORMAL and HAPPY.
I was put on Nardil 40 years ago for Post Partum Psychosis. Dose was a bit low at the beginning, but after a month and an increase in the dosage of Nardil - I was normal. What I experienced with my PPP was beyond any description - I was terribly to come off because I thought my symptoms would come back. They didn’t - very successful treatment. My one worry is Tardive Dyskenesia. Otherwise, I would recommend it for my 19 year old granddaughter.
Was given this for treatment resistant post natal depression and it was the only treatment that worked and gave me my life back.
Have been on for over 30 years. It has allowed me to have a successful career, an active sport and social life. I am now retired but am a qualified tennis tournament referee and could not do this complex task without the concentration level Nardil allows me to have. Whilst early on I did experience the tyramine reaction I find that food and drink with low levels of tyramine are fine. This includes most cheeses, alcoholic drinks except real ale. The only side effect I have had is a loss of libido, which was an issue when I was on 60mg a day, but is unnoticeable at my maintenance level of 30mg a day.
very good experience. has allowed me to function, work, and live a happy life. I have never had any problems with the MAOI diet or any bad effects. It is disgraceful that this medication is so under prescribed.
After many years trying other medications without success, finally I am free of anxiety and depression. Thank you Nardil!
Allowed me to lead a relatively normal life again. Parenting, working and studying all at once. This medication saved my life.
Best antidepressant ever! SSRIs are useless. Nardil is great for anxiety too
I have been on nardil for 30 Years and it has been the only medication that relieved my anxiety. Before Nardil I had problems with agoraphobia and had taken many other medications which did no good. After starting Nardil in a few months I was able to go out in public again without having the annoying anxiety following me. I had very few side effects after starting Nardil and have been very happy with it for the past 30 years.
Helped when nothing else did.
Saved my life
The only antidepressant in 30+ years that has allowed me to function well and work full time and not feel ‘drugged’
only medication that helped after trying numerous other antidepresants.
Best medication ever. Nothing compares. Now in Australia we are experiencing shortage. I have contacted the pharmaceutical companies, and keep pushing them to keep getting it. Everybody on this life-saving medication please do the same. It is still available via Lupin Pharmaceuticals, but with shortages.

Nardil is extremely effective. It totally changed my life, got rid of the severe depression (MDD) that made even getting out of the bed a huge struggle. I was dealing with absolutely no motivation, no pleasure in anything, constant suicidal thoughts, feeling completely overwhelmed. Nardil cured me of all. I need 60 mg minimum dose and it took a while to kick in. The side effects were not so bad, mostly constipation and sleepiness. I do not notice any now. I haven’t had any trouble with the diet restrictions, basically don't even notice it. No SSRI, TCA, atypical antipsychotic, anti-convulsant, etc I've tried comes close to Nardil. So happy i found this medication (which I researched about before telling my doctor).