Phenylephrine/Cocoa

Phenylephrine/cocoa butter rectal is an over-the-counter medication used to temporarily relieve swelling, burning, pain, and itching caused by hemorrhoids.

• Phenylephrine/cocoa butter rectal is available under the following different brand names: Preparation H Suppository

Adult and pediatric dosage

Rectal ointment

• 0.25%/85.39%
• Hemorrhoids
• Adult dosage
• Insert 1 suppository rectally
• May apply up to 4 times/day, especially at night, in the morning, or after bowel movements that may exacerbate hemorrhoid(s)
• Pediatric dosage
• Children below 12 years: Use is dependent on the patient and if the benefit outweighs the risk
• Children above 12 years: Insert 1 suppository rectally
• May apply up to 4 times/day, especially at night, in the morning, or after bowel movements that may exacerbate hemorrhoid(s)

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”

Common side effects of Phenylephrine/Cocoa butter rectal include:

•  mild pain/stinging.

Serious side effects of Phenylephrine/Cocoa butter rectal include:

• allergic reaction: rash, itching/swelling especially of the face/tongue/throat, severe dizziness, and trouble breathing.

Rare side effects of Phenylephrine/Cocoa butter rectal include:

• none 

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first

• Phenylephrine/Cocoa butter rectal has no noted severe interactions with any other drugs.
• Phenylephrine/Cocoa butter rectal has no noted serious interactions with any other drugs
• Phenylephrine/Cocoa butter rectal has no noted moderate interactions with any other drugs.
• Phenylephrine/Cocoa butter rectal has no noted minor interactions with any other drugs. 

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all the products you use. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions or concerns.

Contraindications

• Hypersensitivity

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Phenylephrine/Cocoa butter rectal?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Phenylephrine/Cocoa butter rectal?”

Cautions

• For rectal use only
• Contains phenylephrine, caution for heart disease, hypertension, hyperthyroidism, diabetes, or prostatic hypertrophy
• Discontinue and contact physician if hemorrhoids worsen or do not improve within 7 days
• Discontinue if bleeding, allergic reaction, redness, irritation, swelling, pain, or other symptoms develop or increase

Pregnancy and Lactation

• Use with caution if the benefits outweigh the risks during pregnancy.

Lactation

• Unknown whether distributed in breast milk
• Pregnant or breastfeeding patients should seek the advice of a health professional before using OTC drugs