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Phenylephrine/Witch Hazel Topical: Side Effects, Uses, Dosage, Interactions, Warnings

Phenylephrine/Witch Hazel Topical

What Is Phenylephrine/Witch Hazel Topical and How Does It Work?

Phenylephrine/witch hazel topical is an over-the-counter (OTC) product used to treat hemorrhoids.

Phenylephrine/witch hazel topical is available under the following different brand names: Preparation H Cooling Gel.

What Are the Dosages of Phenylephrine/Witch Hazel Topical?

Dosages of Phenylephrine/Witch Hazel Topical:

Dosage Forms and Strengths

Topical Gel

  • 0.25%/50%

Dosage Considerations – Should be Given as Follows:

Hemorrhoids

  • Adults and children 12 years or older: Apply gel externally to clean, dry hemorrhoidal area
  • It may be applied up to 4 times/day, especially at night, in the morning, or after bowel movement that may exacerbate hemorrhoid(s)
  • Children under 12 years: Use is dependent on patient and if the benefit outweighs the risk

Administration

  • Puncture foil seal using the top end of the tube’s cap when using for the first time
  • Apply gel externally

What Are Side Effects Associated with Using Phenylephrine/Witch Hazel Topical?

There are no side effects reported with the usage of phenylephrine/witch hazel topical

  • If ingested, witch hazel can cause nausea, vomiting, or liver damage

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Phenylephrine/Witch Hazel Topical?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

  • Phenylephrine/witch hazel topical has no listed severe interactions with other drugs.
  • Phenylephrine/witch hazel topical has no listed serious interactions with other drugs.
  • Phenylephrine/witch hazel topical has no listed moderate interactions with other drugs.
  • Phenylephrine/witch hazel topical has no listed mild interactions with other drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

What Are Warnings and Precautions for Phenylephrine/Witch Hazel Topical? 

Warnings

  • This medication contains phenylephrine/witch hazel topical. Do not take Preparation H Cooling Gel if you are allergic to phenylephrine/witch hazel topical or any ingredients contained in this drug.
  • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

Contraindications

  • Hypersensitivity to phenylephrine, witch hazel, or inactive components
  • Oral use

Effects of Drug Abuse

  • No information is available

Short-Term Effects

  • See "What Are Side Effects Associated with Using Phenylephrine/Witch Hazel Topical?”

Long-Term Effects

  • See "What Are Side Effects Associated with Using Phenylephrine/Witch Hazel Topical?”

Cautions

  • For external use only
  • Contains phenylephrine, caution with heart disease, high blood pressure (hypertension), hyperthyroidism, diabetes, or prostatic hypertrophy
  • Discontinue and contact physician if hemorrhoids worsen or do not improve within 7 days
  • Discontinue if bleeding, allergic reaction, redness, irritation, swelling, pain, or other symptoms develop or increase
  • This product should not be placed in the rectum using a mechanical device or fingers

Pregnancy and Lactation

  • Use phenylephrine/witch hazel topical with caution during pregnancy if benefits outweigh risks. Animal studies show risk and human studies are not available or neither animal nor human studies were done.
  • It is unknown if phenylephrine/witch hazel topical is distributed in breast milk.
  • Pregnant or breastfeeding patients should seek the advice of a health professional before using over-the-counter (OTC) drugs.
References
https://reference.medscape.com/drug/preparation-h-cooling-gel-phenylephrine-witch-hazel-topical-999741