Podophyllum Resin

Podophyllum Resin is a prescription medication used for treating warts on the genitals caused by a common sexually transmitted infection

• Podophyllum Resin is available under the following different brand names: Podocon-25

Adult and pediatric dosage

Solution

• 25%

Condyloma Acuminata

Adult and pediatric dosage

• Use a supplied applicator to apply thoroughly to the lesion; allow it to dry thoroughly; leave the first application in contact for only a few minutes (30-40 min) to test for sensitivity

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”

Common side effects of the Podophyllum Resin include:

• swelling, redness, or tenderness of treated skin,
• itching, and
• burning pain

Serious side effects of the Podophyllum Resin include:

• change in the mental state,
• confusion,
• agitation,
• seizures,
• loss of consciousness,
• drowsiness,
• lightheadedness,
• weak or shallow breathing,
• severe constipation,
• little or no urination,
• weakness, numbness, tingling in the arms or legs,
• easy bruising or bleeding (nosebleeds, bleeding gums),
• bloody or tarry stools,
• coughing up blood,
• vomit that looks like coffee grounds,
• upper stomach pain,
• loss of appetite,
• chest pain,
• pounding heartbeats,
• fluttering in the chest, and
• shortness of breath

Rare side effects of the Podophyllum Resin include:

• none 

This is not a complete list of side effects and other serious side effects or health problems that may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

• Podophyllum Resin has no noted severe interactions with any other drugs.
• Podophyllum Resin has no noted serious interactions with any other drugs.
• Podophyllum Resin has no noted moderate interactions with any other drugs.
• Podophyllum Resin has no noted minor interactions with any other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all the products you use. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions or concerns.

Contraindications

• Hypersensitivity
• Avoid EtOH for several hours after treatment
• Mucosal tissue, moles, birthmarks, large/extensive genital warts, bleeding warts
• Avoid in patients with diabetes or circulatory problems
• Breastfeeding

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Podophyllum Resin?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Podophyllum Resin?”

Cautions

• Only to be applied by a doctor
• Limit application to a small area of intact skin
• Avoid eyes; may cause corneal damage
• Use not recommended if wart or surrounding tissue inflamed/irritated
• Use of large amounts of the product is not recommended

Pregnancy and Lactation

• Do not use it in pregnancy. The risks involved outweigh the potential benefits. Safer alternatives exist.
• Lactation
  • Unknown; avoid breastfeeding