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Risperdal vs. Invega for Schizophrenia: Differences & Side Effects

Risperdal vs. Invega

Are Risperdal and Invega the Same Thing?

Risperdal (risperidone) and Invega (paliperidone) are antipsychotic drugs prescribed to treat schizophrenia.

Risperdal is also used to treat bipolar mania and autism.

Side effects of Risperdal and Invega that are similar include dizziness, drowsiness, headache, weight gain, dry mouth, restlessness, nausea, stomach pain or upset, or cough.

What Are Possible Side Effects of Risperdal?

Common side effects of Risperdal include:

  • extrapyramidal effects (sudden, often jerky, involuntary motions of the head, neck, arms, body, or eyes),
  • dizziness,
  • tiredness,
  • drowsiness,
  • fatigue,
  • fever,
  • weight gain,
  • feeling hot or cold,
  • headache,
  • dry mouth,
  • increased appetite,
  • restlessness,
  • anxiety,
  • sleep problems (insomnia),
  • nausea,
  • vomiting,
  • stomach pain,
  • constipation,
  • cough,
  • sore throat,
  • runny or stuffy nose,
  • or skin rash.

Tell your doctor if you experience serious side effects of Risperdal including difficulty swallowing, muscle spasms, shaking (tremor), mental/mood changes, or signs of infection (such as fever, persistent sore throat).

What Are Possible Side Effects of Invega?

Common side effects of Invega include:

  • drowsiness,
  • dizziness,
  • headache,
  • lightheadedness,
  • abdominal/stomach pain,
  • upset stomach,
  • nausea,
  • weight gain,
  • cough,
  • dry mouth,
  • breast swelling or discharge,
  • changes in menstrual periods,
  • restlessness,
  • shaking (tremor),
  • blurred vision,
  • decreased sex drive,
  • impotence, or
  • difficulty having an orgasm.

Tell your doctor if you have serious side effects of Invega including:

  • difficulty swallowing,
  • muscle spasms,
  • mental/mood changes, or
  • signs of infection (such as fever, persistent sore throat),
  • high fever,
  • sweating,
  • confusion,
  • fast or uneven heartbeats,
  • feeling like you might pass out,
  • tremors (uncontrolled shaking),
  • trouble swallowing,
  • sudden numbness or weakness, especially on one side of the body,
  • sudden and severe headache, or problems with vision, speech, or balance,
  • fever, chills, body aches, flu symptoms, or
  • white patches or sores inside your mouth or on your lips.

What is Risperdal?

Risperdal (risperidone) is an atypical antipsychotic prescribed to treat:

  • schizophrenia,
  • bipolar mania,
  • and autism.

What is Invega?

Invega (paliperidone) is an antipsychotic medication used to treat schizophrenia.

What Drugs Interact With Risperdal?

Risperdal may interact with other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety), carbamazepine, fluoxetine, paroxetine, phenytoin, phenobarbital, or rifampin.

Risperdal may also interact with cimetidine, ranitidine, clozapine, valproic acid, or medicines used to treat Parkinson's Disease.

What Drugs Interact With Invega?

Invega may interact with other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety), or carbamazepine.

Invega may also interact with arsenic trioxide, blood pressure medications, droperidol, antibiotics, anti-malaria medications, heart rhythm medicine, medicine to prevent or treat nausea and vomiting, medicines to treat psychiatric disorders, or migraine headache medicines.

How Should Risperdal Be Taken?

Risperdal dose ranges from 0.5 mg to 8mg/day.

How Should Invega Be Taken?

The recommended dose of Invega Extended-Release Tablets for the treatment of schizophrenia in adults is 6 mg once daily, and the recommended dose for adolescents 12-17 years of age is 3 mg once daily.

Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

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If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References

FDA. Risperdal Drug Information.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020272s056,020588s044,021346s033,021444s03lbl.pdf
Invega Product Information.
http://www.invega.com/