Sacrosidase

Sacrosidase is a prescription medication used to treat sucrase deficiency that occurs in people with congenital sucrase-isomaltase deficiency (CSID).

• Sacrosidase is available under the following different brand names: Sucraid

Common side effects of Sacrosidase include:

• stomach pain
• nausea
• vomiting
• diarrhea
• constipation
• sleep problems (insomnia)
• headache
• nervousness
• increased thirst
• dry, hot skin

Serious side effects of Sacrosidase include:

• rash
• itching
• swelling of the face
• tongue, and throat
• trouble with breathing
• chest pain

Rare side effects of Sacrosidase include:

• none

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, coordination loss, unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out.

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Adult and pediatric dosage

Oral concentrate

• 8500 International units/mL

Congenital sucrase-isomaltase deficiency (CSID)

Adult dosage

• 2 mL (17,000 units) orally per meal or snack

Pediatric dosage

• Infants aged older than 5 months
• Infants weighing less than 15 kg: 1 mL (8500 units) orally per meal or snack
• Infants weighing more than 15 kg: 2 mL (17,000 units) orally per meal or snack

Dosage Considerations – Should be Given as Follows:

• See “Dosages”

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, healthcare provider, or pharmacist first.

• Sacrosidase has severe interactions with no other drugs
• Sacrosidase has serious interactions with no other drugs
• Sacrosidase has moderate interactions with no other drugs
• Sacrosidase has minor interactions with the following drug:
  • juice (fruit)

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all the products you use. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your healthcare professional or doctor for additional medical advice, health questions, or concerns.

Contraindications

• Hypersensitivity to Sacrosidase, yeast, yeast products, glycerol, or papain

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Sacrosidase?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Sacrosidase?”

Cautions

• Sacrosidase does not provide isomaltase, dietary starch restriction may be necessary
• Hypersensitivity reactions including bronchospasm reported; initial dose needs to be administered where adequate medical response is available to treat an acute reaction within a few minutes; identify patients at risk by performing a skin test
• Not evaluated for acquired disaccharidase deficiency
• Use caution in patients with diabetes; Sacrosidase enables the absorption of fructose and glucose
• Product may contain papain

Pregnancy and Lactation

• Use with caution if the benefits outweigh the risks during pregnancy. (Not absorbed, unlikely to cause fetal harm)
• Lactation
  • Not absorbed, most likely safe