What Is Shark Cartilage Used For and How Does it Work?
Shark cartilage suggested uses include cancer prevention and treatment, and treatment of arthritis and psoriasis.
Shark cartilage is available under the following different brand names: AE941, Neovastat, and U995.
What Are Side Effects Associated with Using Shark Cartilage?
Side effects of shark cartilage include:
- Dark urine
- Excessive fatigue
- Extreme itchiness
- Nausea
- Diarrhea
- Pain or swelling in the upper right part of the abdomen
- Yellowing of the skin or white parts of eyes
- Constipation
- Dizziness
- Changes in taste
- Low blood pressure
- Upset stomach
- Vomiting
- Weakness
This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
What Other Drugs Interact with Shark Cartilage?
If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.
- Shark Cartilage has moderate interactions with at least 31 different drugs.
- Mild interactions of shark_cartilage include:
- bitter melon
- calcium acetate
- calcium carbonate
- calcium chloride
- calcium citrate
- calcium gluconate
- fenugreek
- gymnema
- interferon alfa 2b
- juice (fruit)
- leflunomide
- thalidomide
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.
What Are Warnings and Precautions for Shark Cartilage?
Warnings
- This medication contains shark cartilage. Do not take AE941, Neovastat, or U995 if you are allergic to shark cartilage or any ingredients contained in this drug.
- Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.
Contraindications
- Pregnancy, lactation
Effects of Drug Abuse
- No information is available.
Short-Term Effects
- See "What Are Side Effects Associated with Using Shark Cartilage?"
Long-Term Effects
- See "What Are Side Effects Associated with Using Shark Cartilage?"
Cautions
- May contain heavy metal contaminants such as mercury and cadmium
- Do not take in high doses or for long periods of time
Pregnancy and Lactation
- Shark cartilage is not recommended for use during pregnancy or while breastfeeding.
From 
Arthritis Resources
https://reference.medscape.com/drug/ae941-neovastat-shark-cartilage-344479