Baie de Goji, Barberry Matrimony Vine, Chinese Boxthorn, Chinese Wolfberry, Di Gu Pi, Digupi, Duke of Argyll's Teaplant, Duke of Argyll's Teatree, Fructus Lycii Chinensis, Fructus Lycii, Fruit de Lycium, Goji Berry, Goji de l'Himalaya, Goji Juice, Gou Qi Zi, Gouqizi, Himalayan Goji, Jus de Goji, Kuko, Licium Barbarum, Lyciet Commun, Lyciet de Barbarie, Lyciet de Chine, Lycii Berries, Lycii Chinensis, Lycii Fructus, Lycii Fruit, Lycium barbarum, Lycium chinense, Lycium Fruit, Matrimony Vine, Ning Xia Gou Qi, Tibetan Goji, Wolfberry.
Goji is a native Chinese deciduous shrub with bright red berries. The dried berries and root bark are used to make medicine.
Goji is used for many conditions, but so far, there isn't enough scientific evidence to determine whether or not it is effective for any of them.
Goji is used for diabetes, high blood pressure, poor circulation, fever, malaria, and cancer. It's also used for erectile dysfunction (ED), dizziness, ringing in the ears (tinnitus); and to reduce fever, sweating, irritability, thirst, nosebleeds, cough, and wheezing.
Some people use goji as an eye tonic for blurred vision, for macular degeneration, and for other eye disorders. Goji is also used to strengthen muscles and bone, and as a blood, liver, and kidney tonic.
In foods, the berries are eaten raw or used in cooking.
The use of goji was first described in the first century AD in Chinese literature. Traditionally, goji has been used to promote longevity. Legend claims that one herbalist who used goji in combination with other tonic herbs lived 252 years.
How does work?
Lycium contains chemicals that might help lower blood pressure and blood sugar.
QUESTION
See AnswerInsufficient Evidence to Rate Effectiveness for...
- Dry eyes. Early research suggests that using Hialid eye drops and drinking a specific product (Runmushu Oral Liquid) containing rehmannia root, figwort, lilyturf root, dendrobium stem, goji fruit, chrysanthemum, and sticktight for one month may improve symptoms of dry eyes better than Hialid eye drops alone in older women.
- Quality of life. Some early research shows that drinking goji juice (GoChi, Freelife International LLC) for 14-30 days improves energy levels, athletic performance, sleep quality, sharpness of the mind, calmness, feelings of health and contentment, mood, and bowel regularity. However, other evidence suggests that drinking the same goji juice does not improve short-term memory or eyesight in healthy adults.
- Weight loss. Early research suggests that drinking goji juice (GoChi, Freelife International LLC) for 2 weeks in addition to following a diet and exercise program may decrease waist size in healthy, overweight adults. However, it does not appear to improve weight or body fat.
- Diabetes.
- High blood pressure.
- Fever.
- Malaria.
- Cancer.
- Blood circulation problems.
- Sexual problems (impotence).
- Dizziness.
- Ringing in the ears (tinnitus).
- Other conditions.
Goji is POSSIBLY SAFE when taken appropriately by mouth, short-term. It can cause some side effects such as nausea and vomiting.
Pregnancy and breast-feeding: Taking goji by mouth during pregnancy is LIKELY UNSAFE. It contains a chemical, betaine, which could cause miscarriage. Don't use goji if you are pregnant or breast-feeding.
Allergy to protein in certain products: Goji might cause an allergic reaction in people who are allergic to tobacco, peaches, tomatoes, and nuts.
Low blood pressure: Goji might lower blood pressure. If your blood pressure is already low, taking goji might make it drop too much.
High blood pressure: Goji might lower blood pressure. It might cause blood pressure to drop too much if you are taking medications for high blood pressure.
Diabetes: Goji root bark might lower blood sugar. It might cause blood sugar to drop too much if you are taking medications for diabetes. Monitor your blood sugar levels carefully.
Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Some medications are changed and broken down by the liver. Goji might decrease how quickly the liver breaks down some medications. Taking goji along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking goji, talk to your healthcare provider if you take any medications that are changed by the liver.
Some medications that are changed by the liver include amitriptyline (Elavil), diazepam (Valium), zileuton (Zyflo), celecoxib (Celebrex), diclofenac (Voltaren), fluvastatin (Lescol), glipizide (Glucotrol), ibuprofen (Advil, Motrin), irbesartan (Avapro), losartan (Cozaar), phenytoin (Dilantin), piroxicam (Feldene), tamoxifen (Nolvadex), tolbutamide (Tolinase), torsemide (Demadex), warfarin (Coumadin), and others.
Medications for diabetes (Antidiabetes drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Goji bark might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking goji bark along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
Medications for high blood pressure (Antihypertensive drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Goji seems to decrease blood pressure. Taking goji along with medications for high blood pressure might cause your blood pressure to go too low.
Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDIURIL), furosemide (Lasix), and many others.
Warfarin (Coumadin)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Warfarin (Coumadin) is used to slow blood clotting. Goji might increase how long warfarin (Coumadin) is in the body, and increase the chances of bruising and bleeding. Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.
The appropriate dose of goji depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for goji. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
SLIDESHOW
See SlideshowNatural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Adams, M., Wiedenmann, M., Tittel, G., and Bauer, R. HPLC-MS trace analysis of atropine in Lycium barbarum berries. Phytochem.Anal. 2006;17(5):279-283. View abstract.
Amagase H, Sun B Nance DM. Clinical studies of improving general well-being by a standardized Lycium barbarum fruit juice. Planta Med 2008;74:1175-1176.
Amagase, H. and Nance, D. M. Lycium barbarum increases caloric expenditure and decreases waist circumference in healthy overweight men and women: pilot study. J.Am.Coll.Nutr. 2011;30(5):304-309. View abstract.
Amagase, H., Sun, B., and Borek, C. Lycium barbarum (goji) juice improves in vivo antioxidant biomarkers in serum of healthy adults. Nutr.Res. 2009;29(1):19-25. View abstract.
Amagase, H., Sun, B., and Nance, D. M. Immunomodulatory effects of a standardized Lycium barbarum fruit juice in Chinese older healthy human subjects. J.Med.Food 2009;12(5):1159-1165. View abstract.
Arroyo-Martinez, Q., Saenz, M. J., Arguelles, Arias F., and Acosta, M. S. Lycium barbarum: a new hepatotoxic "natural" agent? Dig.Liver Dis. 2011;43(9):749. View abstract.
Asano, N., Kato, A., Miyauchi, M., Kizu, H., Tomimori, T., Matsui, K., Nash, R. J., and Molyneux, R. J. Specific alpha-galactosidase inhibitors, N-methylcalystegines--structure/activity relationships of calystegines from Lycium chinense. Eur J Biochem 9-1-1997;248(2):296-303. View abstract.
Benzie, I. F., Chung, W. Y., Wang, J., Richelle, M., and Bucheli, P. Enhanced bioavailability of zeaxanthin in a milk-based formulation of wolfberry (Gou Qi Zi; Fructus barbarum L.). Br J Nutr 2006;96(1):154-160. View abstract.
Breithaupt, D. E., Weller, P., Wolters, M., and Hahn, A. Comparison of plasma responses in human subjects after the ingestion of 3R,3R'-zeaxanthin dipalmitate from wolfberry (Lycium barbarum) and non-esterified 3R,3R'-zeaxanthin using chiral high-performance liquid chromatography. Br.J Nutr. 2004;91(5):707-713. View abstract.
Bucheli, P., Vidal, K., Shen, L., Gu, Z., Zhang, C., Miller, L. E., and Wang, J. Goji berry effects on macular characteristics and plasma antioxidant levels. Optom.Vis.Sci. 2011;88(2):257-262. View abstract.
Chan, H. C., Chang, R. C., Koon-Ching, Ip A., Chiu, K., Yuen, W. H., Zee, S. Y., and So, K. F. Neuroprotective effects of Lycium barbarum Lynn on protecting retinal ganglion cells in an ocular hypertension model of glaucoma. Exp Neurol. 2007;203(1):269-273. View abstract.
Chang, R. C. and So, K. F. Use of Anti-aging Herbal Medicine, Lycium barbarum, Against Aging-associated Diseases. What Do We Know So Far? Cell Mol.Neurobiol. 8-21-2007; View abstract.
Chao, J. C., Chiang, S. W., Wang, C. C., Tsai, Y. H., and Wu, M. S. Hot water-extracted Lycium barbarum and Rehmannia glutinosa inhibit proliferation and induce apoptosis of hepatocellular carcinoma cells. World J Gastroenterol 7-28-2006;12(28):4478-4484. View abstract.
Cheng, C. Y., Chung, W. Y., Szeto, Y. T., and Benzie, I. F. Fasting plasma zeaxanthin response to Fructus barbarum L. (wolfberry; Kei Tze) in a food-based human supplementation trial. Br.J Nutr. 2005;93(1):123-130. View abstract.
Chin, Y. W., Lim, S. W., Kim, S. H., Shin, D. Y., Suh, Y. G., Kim, Y. B., Kim, Y. C., and Kim, J. Hepatoprotective pyrrole derivatives of Lycium chinense fruits. Bioorg.Med Chem Lett 1-6-2003;13(1):79-81. View abstract.
Ching, L. S. and Mohamed, S. Alpha-tocopherol content in 62 edible tropical plants. J.Agric.Food Chem. 2001;49(6):3101-3105. View abstract.
Deng, H. B., Cui, D. P., Jiang, J. M., Feng, Y. C., Cai, N. S., and Li, D. D. Inhibiting effects of Achyranthes bidentata polysaccharide and Lycium barbarum polysaccharide on nonenzyme glycation in D-galactose induced mouse aging model. Biomed Environ.Sci 2003;16(3):267-275. View abstract.
Du, G., Liu, L., and Fang, J. Experimental study on the enhancement of murine splenic lymphocyte proliferation by Lycium barbarum glycopeptide. J Huazhong.Univ Sci Technolog.Med Sci 2004;24(5):518-20, 527. View abstract.
Duan, C. L., Qiao, S. Y., Wang, N. L., Zhao, Y. M., Qi, C. H., and Yao, X. S. [Studies on the active polysaccharides from Lycium barbarum L.]. Yao Xue.Xue.Bao. 2001;36(3):196-199. View abstract.
Franco, M., Monmany, J., Domingo, P., and Turbau, M. [Autoimmune hepatitis triggered by consumption of Goji berries]. Med.Clin.(Barc.) 9-22-2012;139(7):320-321. View abstract.
Fu, J. X. [Measurement of MEFV in 66 cases of asthma in the convalescent stage and after treatment with Chinese herbs]. Zhong.Xi.Yi.Jie.He.Za Zhi. 1989;9(11):658-9, 644. View abstract.
Gan, L. and Zhang, S. [Determination of four fractions of Lycium barbarum polysaccharides in different varieties]. Zhong.Yao Cai. 2001;24(2):107-108. View abstract.
Gan, L., Hua, Zhang S., Liang, Yang, X, and Bi, Xu H. Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum. Int Immunopharmacol. 2004;4(4):563-569. View abstract.
Gan, L., Wang, J., and Zhang, S. [Inhibition the growth of human leukemia cells by Lycium barbarum polysaccharide]. Wei Sheng Yan.Jiu. 2001;30(6):333-335. View abstract.
Gan, L., Zhang, S. H., Liu, Q., and Xu, H. B. A polysaccharide-protein complex from Lycium barbarum upregulates cytokine expression in human peripheral blood mononuclear cells. Eur J Pharmacol 6-27-2003;471(3):217-222. View abstract.
Gomez-Bernal, S., Rodriguez-Pazos, L., Martinez, F. J., Ginarte, M., Rodriguez-Granados, M. T., and Toribio, J. Systemic photosensitivity due to Goji berries. Photodermatol.Photoimmunol.Photomed. 2011;27(5):245-247. View abstract.
Gong, H., Shen, P., Jin, L., Xing, C., and Tang, F. Therapeutic effects of Lycium barbarum polysaccharide (LBP) on irradiation or chemotherapy-induced myelosuppressive mice. Cancer Biother.Radiopharm. 2005;20(2):155-162. View abstract.
Gribanovski-Sassu, O., Pellicciari, R., and Cataldi, Hiughez C. Leaf pigments of Lycium europaeum: seasonal effect on zeaxanthin and lutein formation. Ann Ist.Super.Sanita 1969;5(1):51-53. View abstract.
Ha, K. T., Yoon, S. J., Choi, D. Y., Kim, D. W., Kim, J. K., and Kim, C. H. Protective effect of Lycium chinense fruit on carbon tetrachloride-induced hepatotoxicity. J Ethnopharmacol 1-15-2005;96(3):529-535. View abstract.
Hai-Yang, G., Ping, S., Li, J. I., Chang-Hong, X., and Fu, T. Therapeutic effects of Lycium barbarum polysaccharide (LBP) on mitomycin C (MMC)-induced myelosuppressive mice. J Exp Ther Oncol 2004;4(3):181-187. View abstract.
Han, S. H., Lee, H. H., Lee, I. S., Moon, Y. H., and Woo, E. R. A new phenolic amide from Lycium chinense Miller. Arch Pharm Res 2002;25(4):433-437. View abstract.
Hansel, R. and Huang, J. T. [Lycium chinense, II: A semiquantitative assay of the withanolides (author's transl)]. Arch Pharm (Weinheim) 1977;310(1):35-38. View abstract.
Hansel, R., Huang, J. T., and Rosenberg, D. [Two withanolides from Lycium chinense]. Arch Pharm (Weinheim) 1975;308(8):653-654. View abstract.
He, Y. L., Ying, Y., Xu, Y. L., Su, J. F., Luo, H., and Wang, H. F. [Effects of Lycium barbarum polysaccharide on tumor microenvironment T-lymphocyte subsets and dendritic cells in H22-bearing mice]. Zhong.Xi.Yi.Jie.He.Xue.Bao. 2005;3(5):374-377. View abstract.
Hiserodt, R. D., Adedeji, J., John, T. V., and Dewis, M. L. Identification of monomenthyl succinate, monomenthyl glutarate, and dimenthyl glutarate in nature by high performance liquid chromatography-tandem mass spectrometry. J Agric Food Chem 6-2-2004;52(11):3536-3541. View abstract.
Hsu, H. Y., Yang, J. J., Ho, Y. H., and Lin, C. C. Difference in the effects of radioprotection between aerial and root parts of Lycium chinense. J Ethnopharmacol 1999;64(2):101-108. View abstract.
Huang, L. J., Tian, G. Y., and Ji, G. Z. Structure elucidation of glycan of glycoconjugate LbGp3 isolated from the fruit of Lycium barbarum L. J Asian Nat Prod Res 1999;1(4):259-267. View abstract.
Huang, L. J., Tian, G. Y., Wang, Z. F., Dong, J. B., and Wu, M. P. [Studies on the glycoconjugates and glycans from Lycium barbarum L in inhibiting low density lipoprotein (LDL) peroxidation]. Yao Xue.Xue.Bao. 2001;36(2):108-111. View abstract.
Huang, L., Lin, Y., Tian, G., and Ji, G. [Isolation, purification and physico-chemical properties of immunoactive constituents from the fruit of Lycium barbarum L.]. Yao Xue.Xue.Bao. 1998;33(7):512-516. View abstract.
Huang, X., Yang, M., Wu, X., and Yan, J. [Study on protective action of lycium barbarum polysaccharides on DNA imparments of testicle cells in mice]. Wei Sheng Yan.Jiu. 2003;32(6):599-601. View abstract.
Huang, Y., Lu, J., Shen, Y., and Lu, J. [The protective effects of total flavonoids from Lycium Barbarum L. on lipid peroxidation of liver mitochondria and red blood cell in rats]. Wei Sheng Yan.Jiu. 3-30-1999;28(2):115-116. View abstract.
Huang, Y., Tan, A., Shen, Y., and Lu, J. [Scavenging effect of total flavonoids of lycium barbarum L on active oxygen radicals and inhibitory effects on heat output from L1210 cells]. Wei Sheng Yan.Jiu. 1998;27(2):109-11, 115. View abstract.
IMAI, S., MURATA, T., FUJIOKA, S., and GOTO, M. [ISOLATION OF BETA-SITOSTEROL-BETA-DGLUCOSIDE FROM THE LEAVES OF LYCIUM CHINENSE MILL.]. Yakugaku Zasshi 1963;83:1092. View abstract.
Jia, Y. X., Dong, J. W., Wu, X. X., Ma, T. M., and Shi, A. Y. [The effect of lycium barbarum polysaccharide on vascular tension in two-kidney, one clip model of hypertension]. Sheng Li Xue.Bao. 1998;50(3):309-314. View abstract.
Jung, K., Chin, Y. W., Kim, Y. C., and Kim, J. Potentially hepatoprotective glycolipid constituents of Lycium chinense fruits. Arch Pharm Res 2005;28(12):1381-1385. View abstract.
Kim, H. P., Kim, S. Y., Lee, E. J., Kim, Y. C., and Kim, Y. C. Zeaxanthin dipalmitate from Lycium chinense has hepatoprotective activity. Res Commun.Mol.Pathol Pharmacol 1997;97(3):301-314. View abstract.
Kim, H. P., Lee, E. J., Kim, Y. C., Kim, J., Kim, H. K., Park, J. H., Kim, S. Y., and Kim, Y. C. Zeaxanthin dipalmitate from Lycium chinense fruit reduces experimentally induced hepatic fibrosis in rats. Biol Pharm Bull. 2002;25(3):390-392. View abstract.
Kim, S. Y., Choi, Y. H., Huh, H., Kim, J., Kim, Y. C., and Lee, H. S. New antihepatotoxic cerebroside from Lycium chinense fruits. J Nat Prod 1997;60(3):274-276. View abstract.
Kim, S. Y., Lee, E. J., Kim, H. P., Kim, Y. C., Moon, A., and Kim, Y. C. A novel cerebroside from lycii fructus preserves the hepatic glutathione redox system in primary cultures of rat hepatocytes. Biol Pharm Bull. 1999;22(8):873-875. View abstract.
Lee, C. J., Lee, J. H., Seok, J. H., Hur, G. M., Park, Js J., Bae, S., Lim, J. H., and Park, Y. C. Effects of betaine, coumarin and flavonoids on mucin release from cultured hamster tracheal surface epithelial cells. Phytother Res 2004;18(4):301-305. View abstract.
Lee, D. G., Jung, H. J., and Woo, E. R. Antimicrobial property of (+)-lyoniresinol-3alpha-O-beta-D-glucopyranoside isolated from the root bark of Lycium chinense Miller against human pathogenic microorganisms. Arch Pharm Res 2005;28(9):1031-1036. View abstract.
Lee, D. G., Park, Y., Kim, M. R., Jung, H. J., Seu, Y. B., Hahm, K. S., and Woo, E. R. Anti-fungal effects of phenolic amides isolated from the root bark of Lycium chinense. Biotechnol.Lett 2004;26(14):1125-1130. View abstract.
Li, G., Yang, J., Ren, B., and Wang, Z. [Effect of lycium barbarum L on defending free radicals of mice caused by hypoxia]. Wei Sheng Yan.Jiu. 2002;31(1):30-31. View abstract.
Li, J., Qu, W. J., Zhang, S. J., and Lv, H. Y. [Study on antioxidant activity of pigment of Lycium ruthenicum]. Zhongguo Zhong.Yao Za Zhi. 2006;31(14):1179-1183. View abstract.
Lin, J. Y., Lu, S., Liou, Y. L., and Liou, H. L. Increased IgA and IgG serum levels using a novel yam-boxthorn noodle in a BALB/c mouse model. Food Chem Toxicol 2006;44(2):170-178. View abstract.
Lin, R. D., Hou, W. C., Yen, K. Y., and Lee, M. H. Inhibition of monoamine oxidase B (MAO-B) by Chinese herbal medicines. Phytomedicine 2003;10(8):650-656. View abstract.
Liu, B. [Effects of Lycium barbarum L and Drynaria fortunei J Smith on in vitro attachment and growth of human gingival fibroblasts on root surfaces]. Zhonghua Kou Qiang.Yi.Xue.Za Zhi. 1992;27(3):159-61, 190. View abstract.
Liu, X. L., Sun, J. Y., Li, H. Y., Zhang, L., and Qian, B. C. [Extraction and isolation of active component for inhibiting PC3 cell proliferation in vitro from the fruit of Lycium barbarum L.]. Zhongguo Zhong.Yao Za Zhi. 2000;25(8):481-483. View abstract.
Lu, C. X. and Cheng, B. Q. [Radiosensitizing effects of Lycium barbarum polysaccharide for Lewis lung cancer]. Zhong.Xi.Yi.Jie.He.Za Zhi. 1991;11(10):611-2, 582. View abstract.
Lu, X., Xian, X., Lu, W., Wu, X., and Gu, H. [The regulation of Lycium barbarum on apoptosis of rat spleen in vitro]. Zhong.Yao Cai. 1999;22(5):250-251. View abstract.
Luo, Q., Cai, Y., Yan, J., Sun, M., and Corke, H. Hypoglycemic and hypolipidemic effects and antioxidant activity of fruit extracts from Lycium barbarum. Life Sci 11-26-2004;76(2):137-149. View abstract.
Luo, Q., Li, Z., Huang, X., Yan, J., Zhang, S., and Cai, Y. Z. Lycium barbarum polysaccharides: Protective effects against heat-induced damage of rat testes and H2O2-induced DNA damage in mouse testicular cells and beneficial effect on sexual behavior and reproductive function of hemicastrated rats. Life Sci 7-10-2006;79(7):613-621. View abstract.
Luo, Q., Yan, J., and Zhang, S. [Effects of pure and crude Lycium barbarum polysaccharides on immunopharmacology]. Zhong.Yao Cai. 1999;22(5):246-249. View abstract.
Luo, Q., Yan, J., and Zhang, S. [Isolation and purification of Lycium barbarum polysaccharides and its antifatigue effect]. Wei Sheng Yan.Jiu. 3-30-2000;29(2):115-117. View abstract.
Miao, Y., Xiao, B., Jiang, Z., Guo, Y., Mao, F., Zhao, J., Huang, X., and Guo, J. Growth inhibition and cell-cycle arrest of human gastric cancer cells by Lycium barbarum polysaccharide. Med.Oncol. 2010;27(3):785-790. View abstract.
Mino, Y. Amino acid sequences of ferredoxins from Scopolia japonica and Lycium chinense: their similarities to that of Datura arborea. Biol Pharm Bull. 2002;25(10):1367-1369. View abstract.
Monzon, Ballarin S., Lopez-Matas, M. A., Saenz, Abad D., Perez-Cinto, N., and Carnes, J. Anaphylaxis associated with the ingestion of Goji berries (Lycium barbarum). J.Investig.Allergol.Clin.Immunol. 2011;21(7):567-570. View abstract.
Ni, H., Qing, D., Kaisa, S., and Lu, J. [The study on the effect of LBP on cleaning hydroxygen free radical by EPR technique]. Zhong.Yao Cai. 2004;27(8):599-600. View abstract.
Parr, A. J., Mellon, F. A., Colquhoun, I. J., and Davies, H. V. Dihydrocaffeoyl polyamines (kukoamine and allies) in potato (Solanum tuberosum) tubers detected during metabolite profiling. J Agric Food Chem 6-29-2005;53(13):5461-5466. View abstract.
Paul Hsu, C. H., Nance, D. M., and Amagase, H. A meta-analysis of clinical improvements of general well-being by a standardized Lycium barbarum. J.Med.Food 2012;15(11):1006-1014. View abstract.
Peng, X. and Tian, G. Structural characterization of the glycan part of glycoconjugate LbGp2 from Lycium barbarum L. Carbohydr Res 3-9-2001;331(1):95-99. View abstract.
Peng, X. M., Wang, Z. F., and Tian, G. Y. [Physico-chemical properties and activity of glycoconjugate LbGp2 from Lycium barbarum L.]. Yao Xue.Xue.Bao. 2001;36(8):599-602. View abstract.
Peng, Y., Ma, C., Li, Y., Leung, K. S., Jiang, Z. H., and Zhao, Z. Quantification of zeaxanthin dipalmitate and total carotenoids in Lycium fruits (Fructus Lycii). Plant Foods Hum.Nutr 2005;60(4):161-164. View abstract.
Qin, X., Yamauchi, R., Aizawa, K., Inakuma, T., and Kato, K. Structural features of arabinogalactan-proteins from the fruit of Lycium chinense Mill. Carbohydr Res 6-22-2001;333(1):79-85. View abstract.
Ren, B., Ma, Y., Shen, Y., and Gao, B. [Protective action of Lycium barbarum L. (LbL) and betaine on lipid peroxidation of erythrocyte membrane induced by H2O2]. Zhongguo Zhong.Yao Za Zhi. 1995;20(5):303-4, inside. View abstract.
Shabana, M. M., Mirhom, Y. W., Genenah, A. A., Aboutabl, E. A., and Amer, H. A. Study into wild Egyptian plants of potential medicinal activity. Ninth communication: hypoglycaemic activity of some selected plants in normal fasting and alloxanised rats. Arch Exp Veterinarmed. 1990;44(3):389-394. View abstract.
Shin, Y. G., Cho, K. H., Kim, J. M., Park, M. K., and Park, J. H. Determination of betaine in Lycium chinense fruits by liquid chromatography-electrospray ionization mass spectrometry. J Chromatogr A 10-1-1999;857(1-2):331-335. View abstract.
Sin, H. P., Liu, D. T., and Lam, D. S. Lifestyle modification, nutritional and vitamins supplements for age-related macular degeneration. Acta Ophthalmol. 2013;91(1):6-11. View abstract.
Stoner, G. D., Wang, L. S., Seguin, C., Rocha, C., Stoner, K., Chiu, S., and Kinghorn, A. D. Multiple berry types prevent N-nitrosomethylbenzylamine-induced esophageal cancer in rats. Pharm.Res 2010;27(6):1138-1145. View abstract.
Sun, H., Hu, Y., Zhang, J. M., Li, S. Y., and He, W. [Effects of one Chinese herbs on improving cognitive function and memory of Alzheimer's disease mouse models]. Zhongguo Zhong.Yao Za Zhi. 2003;28(8):751-754. View abstract.
Suzuki, M., Osawa, S., and Hirano, M. A Lycium chinense Miller component inducing ovulation in adult female rabbits. Tohoku J Exp Med 1972;106(3):219-231. View abstract.
Tierra, M. Planetary Herbology. Twin Lakes: Lotus Press;1988.
Toyada-Ono, Y., Maeda, M., Nakao, M., Yoshimura, M., Sugiura-Tomimori, N., Fukami, H., Nishioka, H., Miyashita, Y., and Kojo, S. A novel vitamin C analog, 2-O-(beta-D-Glucopyranosyl)ascorbic acid: examination of enzymatic synthesis and biological activity. J Biosci.Bioeng. 2005;99(4):361-365. View abstract.
Toyoda-Ono, Y., Maeda, M., Nakao, M., Yoshimura, M., Sugiura-Tomimori, N., and Fukami, H. 2-O-(beta-D-Glucopyranosyl)ascorbic acid, a novel ascorbic acid analogue isolated from Lycium fruit. J Agric Food Chem 4-7-2004;52(7):2092-2096. View abstract.
Vidal, K., Bucheli, P., Gao, Q., Moulin, J., Shen, L. S., Wang, J., Blum, S., and Benyacoub, J. Immunomodulatory effects of dietary supplementation with a milk-based wolfberry formulation in healthy elderly: a randomized, double-blind, placebo-controlled trial. Rejuvenation.Res. 2012;15(1):89-97. View abstract.
Wang, L. H., Jiang, Z. S., and Chen, Z. F. [Inhibitory effects of Chinese medicines on SOS responses in E. coli and their mechanism]. Yi.Chuan Xue.Bao. 1991;18(1):90-96. View abstract.
Wang, Y., Zhao, H., Sheng, X., Gambino, P. E., Costello, B., and Bojanowski, K. Protective effect of Fructus Lycii polysaccharides against time and hyperthermia-induced damage in cultured seminiferous epithelium. J Ethnopharmacol. 2002;82(2-3):169-175. View abstract.
Wei, D., Li, Y. H., and Zhou, W. Y. [Observation on therapeutic effect of runmushu oral liquid in treating xerophthalmia in postmenopausal women]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2009;29(7):646-649. View abstract.
Wei, R. B., Huo, H. R., Li, X. Q., Zhou, A. X., Shen, H., and Tian, J. L. [Study on antiinflammatory effect of a compound TCM agent containing ant extractive in animal models]. Zhongguo Zhong.Yao Za Zhi. 2002;27(3):215-218. View abstract.
Wei, Y., Zhang, T. Y., Zhang, S., and Liu, Q. H. [Separation of standard proteins and actual samples using cross-axis counter current chromatography]. Se.Pu. 2001;19(2):188-190. View abstract.
Weller, P. and Breithaupt, D. E. Identification and quantification of zeaxanthin esters in plants using liquid chromatography-mass spectrometry. J.Agric.Food Chem. 11-19-2003;51(24):7044-7049. View abstract.
Wineman, E., Portugal-Cohen, M., Soroka, Y., Cohen, D., Schlippe, G., Voss, W., Brenner, S., Milner, Y., Hai, N., and Ma'or, Z. Photo-damage protective effect of two facial products, containing a unique complex of Dead Sea minerals and Himalayan actives. J.Cosmet.Dermatol. 2012;11(3):183-192. View abstract.
Wu, B. Y., Zou, J. H., and Meng, S. C. [Effect of wolfberry fruit and epimedium on DNA synthesis of the aging-youth 2BS fusion cells]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2003;23(12):926-928. View abstract.
Wu, H., Guo, H., and Zhao, R. Effect of Lycium barbarum polysaccharide on the improvement of antioxidant ability and DNA damage in NIDDM rats. Yakugaku Zasshi 2006;126(5):365-371. View abstract.
Wu, S. J., Ng, L. T., and Lin, C. C. Antioxidant activities of some common ingredients of traditional chinese medicine, Angelica sinensis, Lycium barbarum and Poria cocos. Phytother Res 2004;18(12):1008-1012. View abstract.
Xie, C., Xu, L. Z., Li, X. M., Li, K. M., Zhao, B. H., and Yang, S. L. [Studies on chemical constituents in fruit of Lycium barbarum L.]. Zhongguo Zhong.Yao Za Zhi. 2001;26(5):323-324. View abstract.
Xie, H. and Zhang, S. [Determination of taurine in Lycium barbarum L. by high performance liquid chromatography with OPA-urea pre-column derivatization]. Se.Pu. 1997;15(1):54-56. View abstract.
Xu, M., Zhang, H., and Wang, Y. [The protective effects of Lycium barbarum polysaccharide on alloxan-induced isolated islet cells damage in rats]. Zhong.Yao Cai. 2002;25(9):649-651. View abstract.
Xu, S. L., Huang, J., and Tian, G. Y. [Effects of LbGp on the intracellular free calcium concentration of cardiomyocytes induced by hypoxia and KCl]. Zhongguo Zhong.Yao Za Zhi. 2005;30(7):534-538. View abstract.
Xu, Y., He, L., Xu, L., and Liu, Y. [Advances in immunopharmacological study of Lycium barbarum L.]. Zhong.Yao Cai. 2000;23(5):295-298. View abstract.
Yahara, S., Shigeyama, C., Ura, T., Wakamatsu, K., Yasuhara, T., and Nohara, T. Cyclic peptides, acyclic diterpene glycosides and other compounds from Lycium chinense Mill. Chem Pharm Bull.(Tokyo) 1993;41(4):703-709. View abstract.
Yin, J., Tezuka, Y., Kouda, K., Tran, Q. L., Miyahara, T., Chen, Y., and Kadota, S. Antiosteoporotic activity of the water extract of Dioscorea spongiosa. Biol Pharm Bull. 2004;27(4):583-586. View abstract.
Yu, M. S., Ho, Y. S., So, K. F., Yuen, W. H., and Chang, R. C. Cytoprotective effects of Lycium barbarum against reducing stress on endoplasmic reticulum. Int J Mol.Med 2006;17(6):1157-1161. View abstract.
Yu, M. S., Leung, S. K., Lai, S. W., Che, C. M., Zee, S. Y., So, K. F., Yuen, W. H., and Chang, R. C. Neuroprotective effects of anti-aging oriental medicine Lycium barbarum against beta-amyloid peptide neurotoxicity. Exp Gerontol. 2005;40(8-9):716-727. View abstract.
Zhang, B., Zhang, X., and Li, W. [The injury of Xenopus laevis oocytes membrane and its acetylcholine receptor by free radical and the protection of lycium barbarum polysaccharide]. Zhongguo Ying.Yong.Sheng Li Xue.Za Zhi. 1997;13(4):322-325. View abstract.
Zhang, M., Chen, H., Huang, J., Li, Z., Zhu, C., and Zhang, S. Effect of lycium barbarum polysaccharide on human hepatoma QGY7703 cells: inhibition of proliferation and induction of apoptosis. Life Sci 3-18-2005;76(18):2115-2124. View abstract.
Zhang, X. [Experimental research on the role of Lycium barbarum polysaccharide in anti-peroxidation]. Zhongguo Zhong.Yao Za Zhi. 1993;18(2):110-2, 128. View abstract.
Zhao, H., Alexeev, A., Chang, E., Greenburg, G., and Bojanowski, K. Lycium barbarum glycoconjugates: effect on human skin and cultured dermal fibroblasts. Phytomedicine 2005;12(1-2):131-137. View abstract.
Zhao, R., Li, Q., and Xiao, B. Effect of Lycium barbarum polysaccharide on the improvement of insulin resistance in NIDDM rats. Yakugaku Zasshi 2005;125(12):981-988. View abstract.
Zhi, F., Zheng, W., Chen, P., and He, M. [Study on the extraction process of polysaccharide from Lycium barbarum]. Zhong.Yao Cai. 2004;27(12):948-950. View abstract.
Zhou, X., Xu, G., and Wang, Q. [Chemical constituents in the roots of Lycium chinense Mill.]. Zhongguo Zhong.Yao Za Zhi. 1996;21(11):675-6, 704. View abstract.
Agricultural Research Service. Dr. Duke's phytochemical and ethnobotanical databases. www.ars-grin.gov/cgi-bin/duke/farmacy2.pl?575 (Accessed 31 January 2001).
Amagase H, Nance DM. A randomized, double-blind, placebo-controlled, clinical study of the general effects of a standardized Lycium barbarum (goji) juice, GoChi. J Altern Complement Med 2008;14:403-12. View abstract.
Cao GW, Yang WG, Du P. [Observation of the effects of LAK/IL-2 therapy combining with Lycium barbarum polysaccharides in the treatment of 75 cancer patients]. Chung Hua Chung Liu Tsa Chih 1994;16:428-31. View abstract.
Carnes, J., de Larramendi, C. H., Ferrer, A., Huertas, A. J., Lopez-Matas, M. A., Pagan, J. A., Navarro, L. A., Garcia-Abujeta, J. L., Vicario, S., and Pena, M. Recently introduced foods as new allergenic sources: sensitisation to Goji berries (Lycium barbarum). Food Chem. 4-15-2013;137(1-4):130-135. View abstract.
Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
Huang KC. The Pharmacology of Chinese Herbs. 2nd ed. Boca Raton, FL: CRC Press, LLC 1999.
Kim SY, Lee EJ, Kim HP, et al. LCC, a cerebroside from lycium chinense, protects primary cultured rat hepatocytes exposed to galactosamine. Phytother Res 2000;14:448-51. View abstract.
Lam AY, Elmer GW, Mohutsky MA. Possible interaction between warfarin and Lycium Barbarum. Ann Pharmacother 2001;35:1199-201. View abstract.
Larramendi, C. H., Garcia-Abujeta, J. L., Vicario, S., Garcia-Endrino, A., Lopez-Matas, M. A., Garcia-Sedeno, M. D., and Carnes, J. Goji berries (Lycium barbarum): risk of allergic reactions in individuals with food allergy. J.Investig.Allergol.Clin.Immunol. 2012;22(5):345-350. View abstract.
Law M. Plant sterol and stanol margarines and health. BMJ 2000;320:861-4. View abstract.
Leung H, Hung A, Hui AC, Chan TY. Warfarin overdose due to the possible effects of Lycium barbarum L. Food Chem Toxicol 2008;46:1860-2. View abstract.
Rivera, C. A., Ferro, C. L., Bursua, A. J., and Gerber, B. S. Probable interaction between Lycium barbarum (goji) and warfarin. Pharmacotherapy 2012;32(3):e50-e53. View abstract.