1-[2,4-Dihydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one, 1-[2-(Beta-D-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone, Floridzin, Phloretin-2'-O-glucoside, Phloridzin, Phlorizoside, Phlorrhizin.
Phlorizin is a substance found in some fruit trees, such as the bark of apple trees. It is used to make medicine.
People take phlorizin by mouth for fever, malaria, diabetes, and as an antioxidant.
How does work?
Phlorizin prevents the kidneys from reabsorbing sugar. This lowers blood sugar levels. Phlorizin might also slow tumor growth and lessen bone loss.
Insufficient Evidence to Rate Effectiveness for...
- Diabetes.
- Fever.
- Malaria.
- Other conditions.
It isn't known if phlorizin is safe. It might cause blood sugar levels to drop too low. It might also cause people to feel very hungry.
QUESTION
Next to red peppers, you can get the most vitamin C from ________________. See AnswerDiabetes: Phlorizin might lower blood sugar. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use phlorizin.
Surgery: Phlorizin might lower blood sugar. There is some concern that it might interfere with blood sugar control during and after surgery. Stop using phlorizin at least 2 weeks before a scheduled surgery.
Medications for diabetes (Antidiabetes drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Phlorizin might lower blood sugar. Diabetes medications are also used to lower blood sugar. Taking phlorizin along with diabetes medications might cause blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
The appropriate dose of phlorizin depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for phlorizin. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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