Tafluprost

Tafluprost is a prescription medication used for reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

• Tafluprost is available under the following different brand names: Zioptan.

Common side effects of Tafluprost include:

• eye redness
• eye stinging or irritation
• eye itching
• cataracts
• dry eyes
• eye pain
• blurred vision
• headache
• common cold symptoms
• cough
• eye inflammation (allergic conjunctivitis)
• urinary tract infections

Serious side effects of Tafluprost include:

• vision changes
• eye pain/swelling
• swelling/redness of the eyelids

Rare side effects of Tafluprost include:

• none 

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, coordination loss, unsteady, very stiff muscles, high fever, profuse sweating, or tremors.
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights.
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out.

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Adult dosage

Ophthalmic solution

• 0.0015% (0.015mg/mL)

Elevated intraocular pressure

Adult dosage

• Instill 1 drop in the affected eye(s) once daily in the evening.

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, healthcare provider, or pharmacist first.

• Tafluprost has severe interactions with no other drugs
• Tafluprost has serious interactions with the following drugs:
  • bimatoprost
  • latanoprost
  • latanoprostene bunod ophthalmic
  • travoprost ophthalmic
• Tafluprost has moderate interactions with at least 31 other drugs.
• Tafluprost has minor interactions with no other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all the products you use. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your healthcare professional or doctor for additional medical advice, health questions, or concerns.

Contraindications

• None

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Tafluprost?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Tafluprost?”

Cautions

• Causes changes to pigmented tissues; most frequently reported changes have been of the iris, eyelid, and eyelashes; pigmentation changes of the iris are likely permanent Increases in length, color, thickness, and number of eyelashes
• Caution with active intraocular inflammation (may exacerbate the condition)
• Macular edema reported; caution in aphakic patients, in pseudophakic patients with a torn posterior lens capsule, or with known risk factors for macular edema

Pregnancy and Lactation

• Use with caution if the benefits outweigh the risks during pregnancy. Teratogenic when administered IV in rats and rabbits
• Lactation
  • Unknown whether distributed in breast milk