Tapinarof Topical

Tapinarof Topical is a prescription medication used for the treatment of plaque psoriasis.

• Tapinarof Topical is available under the following different brand names: Vtama

Common side effects of Tapinarof Topical include:

• nasal congestion, 
• sore throat, 
• respiratory tract infection, 
• runny or stuffy nose, 
• sneezing, 
• cough, 
• cold symptoms, 
• headache, 
• itching, and
• flu-like symptoms

Serious side effects of Tapinarof Topical include:

• hives, 
• difficulty breathing, 
• swelling of the face, lips, tongue, or throat, 
• dizziness
• inflammation of hair follicles at the application site, and
• itchy rash

Rare side effects of Tapinarof Topical include:

• none 

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out.

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Adult dosage

Topical cream

• 10 mg/g (1%)

Plaque Psoriasis

Adult dosage

• Apply a thin layer to affected areas once daily

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

• Tapinarof Topical has no noted severe interactions with any other drugs.
• Tapinarof Topical has no noted serious interactions with any other drugs.
• Tapinarof Topical has no noted moderate interactions with any other drugs.
• Tapinarof Topical has no noted minor interactions with any other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all your products. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your healthcare professional or doctor for additional medical advice, or if you have health questions or concerns.

Contraindications

• None

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Tapinarof Topical?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Tapinarof Topical?”

Cautions

• Apply the medication to skin lesions only, and avoid unaffected areas of skin
• Advise patients that medication is for external use only

Pregnancy and Lactation

• Available data in pregnant women are insufficient to evaluate for drug-associated risk of major birth defects, miscarriage, or other adverse maternal or fetal outcomes
• Lactation
  • No data is available regarding the presence of the drug in human milk, its effects on the breastfed infant, or milk production; the drug was detected in rat offspring following subcutaneous administration to pregnant female rats, which suggests that the drug was transferred into the milk of lactating rats; when the drug is present in animal milk, the drug will likely be present in human milk
  • Developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for therapy and any potential adverse effects on the breastfed infant from therapy or underlying maternal condition