Tradipitant

Tradipitant is used for the prevention of vomiting caused by motion (motion sickness).

• Tradipitant is available under the following different brand names: Nereus.

Common side effects of tradipitant include:

• Drowsiness
• Headache
• Tiredness

Serious side effects of tradipitant include:

• Decreased Alertness or Coordination: Tradipitant can affect your alertness or coordination. Do not drive or do other activities that require alertness or coordination until you know how tradipitant affects you. This effect may be worse if you also take other medicines that cause drowsiness or strong liver enzyme (CYP3A4) inhibitors.

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Dosage Forms & Strengths

• Capsule: 85 mg

Prevention of vomiting induced by motion

Adult Dose:

• 85 mg or 170 mg taken as a single dose by mouth.
• Take the dose about 60 minutes before an activity that is expected to cause motion sickness.
• Do not take more than one dose in a 24-hour period.
• Take on an empty stomach, at least 1 hour before or 2 hours after a full meal.

Pediatric Dose:

• Safety and effectiveness in children have not been established.

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if tradipitant is right for you.

Some other medicines may alter the blood levels of tradipitant. Tell your health care provider about all medicines that you take or have recently taken.

This may not be a complete list of medicines that can interact with tradipitant. Always check with your health care provider.

Contraindications:

• No Known Contraindications.

Cautions:

• Liver Problems: Tradipitant should be avoided in people with any degree of liver problems (hepatic impairment).
• Kidney Problems: Tradipitant should be avoided in people with severe kidney problems (renal impairment).

Pregnancy:

• There is not enough information to know if tradipitant is safe to use during pregnancy or if it causes birth defects or miscarriage.

Lactation:

• It is not known if the medicine passes into breast milk or if it can affect a nursing baby.