Uterine rupture: A tear in the uterus. A uterine rupture is a very serious situation. Causes include trauma, labor with an unusually big baby, multiple gestation, and vaginal delivery after a prior C-section (in which the old C-section scar ruptures). Uterine rupture can lead to hysterectomy, urologic injury, the need for blood transfusion, and even the death of the mother and baby.
