Vitreous: A clear, jelly-like substance that fills the middle of the eye. Also called the vitreous humor, "humor" in medicine referring to a fluid (or semifluid) substance. From Eye Health Resources Supplements for Vision and Healthy Eyes12 Devices That Can Help Your Low VisionOvercoming DME: A Guide to Treatment Featured Centers What Are the Best PsA Treatments for You?Understanding Biologics 10 Things People With Depression Wish You Knew