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Chlor-Trimeton (Chlorpheniramine Maleate): Side Effects, Uses, Dosage, Interactions, Warnings

Chlor-Trimeton

Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 5/31/2023

Drug Summary

What Is Chlor-Trimeton?

Chlor-Trimeton (chlorpheniramine maleate) is an antihistamine used to treat sneezing, itching, watery eyes, and runny nose caused by allergies or the common cold. Chlor-Trimeton is available in generic form and over-the-counter (OTC).

What Are Side Effects of Chlor-Trimeton?

Common side effects of Chlor-Trimeton include:

  • drowsiness,
  • dizziness,
  • blurred vision,
  • dry mouth/nose/throat,
  • nausea,
  • stomach pain,
  • constipation,
  • problems with memory or concentration,
  • nervousness, or
  • restlessness or excitability (especially in children).

Dosage for Chlor-Trimeton

Dose for Chlor-Trimeton for adults and children 12 years of age and older: One tablet every 4 to 6 hours, not to exceed 6 tablets in 24 hours or as directed by a physician. Children 6 through 11 years: Half the adult dose every 4 to 6 hours, not to exceed 3 whole tablets in 24 hours. Children under 6: Consult a doctor.

What Drugs, Substances, or Supplements Interact with Chlor-Trimeton?

Some medications may interact with Chlor-Trimeton, including antidepressants, diuretics (water pills), glycopyrrolate, mepenzolate, aspirin or salicylates, atropine, belladonna, benztropine, dimenhydrinate, methscopolamine, scopolamine, bronchodilators, MAO inhibitors, bladder or urinary medications, or irritable bowel medications. Tell your doctor all drugs you are taking.

Chlor-Trimeton During Pregnancy and Breastfeeding

Chlor-Trimeton is not expected to be harmful to a fetus. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Chlor-Trimeton can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breastfeeding.

Additional Information

Our Chlor-Trimeton Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

Description for Chlor-Trimeton

Chlor-Trimeton (chlorpheniramine maleate)

Active ingredient (in each tablet): Chlorpheniramine Maleate 12 mg.

Inactive ingredients: acacia, calcium phosphate tribasic, calcium sulfate, carnauba wax, corn starch, FD&C yellow No. 6, FD&C yellow No. 6 aluminum lake, lactose monohydrate, magnesium stearate, neutral soap, oleic acid, pharmaceutical ink, povidone, rosin, sucrose, talc, titanium dioxide, white wax, zein

Chlorpheniramine

Uses for Chlor-Trimeton

Purpose: Antihistamine

Uses:

  • temporarily relieves the following symptoms due to hay fever or other upper respiratory allergies:
    • sneezing
    • runny nose
    • itchy, watery eyes
    • itching of the nose or throat

Dosage for Chlor-Trimeton

Directions

  • adults and children 12 years and over: 1 tablet every 12 hours. Do not exceed 2 tablets in 24 hours.
  • children under 12 years of age: ask a doctor

HOW SUPPLIED

Other information

  • each tablet contains: calcium 30 mg
  • store between 20 and 25°C (68 and 77°F)

Side Effects for Chlor-Trimeton

When using this product

  • excitability may occur, especially in children
  • drowsiness may occur
  • avoid alcoholic beverages
  • alcohol, sedatives and tranquilizers may increase drowsiness
  • use caution when driving a motor vehicle or operating machinery

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Drug Interactions for Chlor-Trimeton

No information provided.

Warnings for Chlor-Trimeton

Ask a doctor before use if you have

Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers

When using this product

  • excitability may occur, especially in children
  • drowsiness may occur
  • avoid alcoholic beverages
  • alcohol, sedatives and tranquilizers may increase drowsiness
  • use caution when driving a motor vehicle or operating machinery

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

Precautions for Chlor-Trimeton

No information provided.

Overdose Information for Chlor-Trimeton

No information provided.

Contraindications for Chlor-Trimeton

Ask a doctor before use if you have

  • a breathing problem such as emphysema or chronic bronchitis
  • glaucoma
  • trouble urinating due to an enlarged prostate gland

Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers

Clinical Pharmacology for Chlor-Trimeton

Competes with histamine for H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract.

Patient Information for Chlor-Trimeton

See WARNINGS section.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.