Chloroprocaine Ophthalmic

Chloroprocaine Ophthalmic is a prescription topical gel indicated for ocular surface anesthesia.

• Chloroprocaine Ophthalmic is available under the following different brand names: Iheezo

Common side effects of Chloroprocaine Ophthalmic include:

• mydriasis,
• conjunctival hyperemia
• eye irritation.

Serious side effects of Chloroprocaine Ophthalmic include:

• none

Rare side effects of Chloroprocaine Ophthalmic include:

• none 

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, light-headedness, or passing out

This is not a complete list of side effects and other serious side effects or health problems that may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Adult dosage

Ophthalmic gel

• 3% (24 mg chloroprocaine/800 mg gel) as 1.25 mL single-use vial

Ocular Surface Anesthesia

Adult dosage

• Apply 3 drops topically to the ocular surface in the area of planned procedure
• May reapply as needed to maintain an anesthetic effect

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, healthcare provider, or pharmacist first.

• Chloroprocaine Ophthalmic has no noted severe interactions with any other drugs.
• Chloroprocaine Ophthalmic has no noted serious interactions with any other drugs.
• Chloroprocaine Ophthalmic has no noted moderate interactions with any other drugs.
• Chloroprocaine Ophthalmic has no noted minor interactions with any other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all the products you use. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your healthcare professional or doctor for additional medical advice, or if you have health questions or concerns.

Contraindications

• History of hypersensitivity to product components

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Chloroprocaine Ophthalmic?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Chloroprocaine Ophthalmic?”

Cautions

• Not for injection or intraocular administration
• Corneal injury owing to insensitivity may occur; instruct patients to not touch their eye(s) for at least 10-20 minutes after anesthetic applied to avoid accidental injuries
• Prolonged use of topical ocular anesthetic may produce permanent corneal opacification and ulceration with accompanying visual loss
• Do not touch the dropper tip to any surface to avoid contaminating the gel
• Indicated for administration under the direct supervision of a healthcare provider; not intended for patient self-administration

Pregnancy and Lactation

• There are no adequate and well-controlled studies of chloroprocaine use in pregnant women to inform drug-associated risk. There are no animal reproduction studies for chloroprocaine
• Lactation
  • There are no data on the presence of chloroprocaine in human milk, the effects on the breastfed infant, or milk production. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for chloroprocaine and any potential adverse effects on the breastfed infant from this drug