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Deconex Capsule (Guaifenesin, Phenylephrine Hydrochloride): Side Effects, Uses, Dosage, Interactions, Warnings

Deconex

Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 10/10/2022

Drug Summary

What Is Deconex?

Deconex (guaifenesin, phenylephrine hydrochloride capsule) is a combination of an expectorant and a nasal decongestant indicated to temporarily relieve the following symptoms due to the common cold, hay fever (allergic rhinitis), or other upper respiratory allergies: helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes and make coughs more productive, relieves nasal congestion, and reduces swelling of nasal passages. Deconex is available over-the-counter (OTC).

What Are Side Effects of Deconex?

Deconex may cause serious side effects including:

  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • fast, pounding, or uneven heartbeat,
  • severe anxiety, and
  • nervousness

Get medical help right away, if you have any of the symptoms listed above.

Common side effects of Deconex include:

  • dizziness,
  • headache,
  • nausea,
  • trouble sleeping,
  • nervousness,
  • excitability, or
  • weakness.

Seek medical care or call 911 at once if you have the following serious side effects:

  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheadedness, or passing out;
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Deconex

The dose of Deconex for adults and children 12 years of age and over is 1 capsule every 4 hours, not to exceed 6 capsules in 24 hours.

What Drugs, Substances, or Supplements Interact with Deconex?

Deconex may interact with monoamine oxidase inhibitors (MAOIs). Tell your doctor all medications and supplements you use.

Deconex During Pregnancy or Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Deconex. Consult your doctor before breastfeeding.

Additional Information

Our Deconex (guaifenesin, phenylephrine hydrochloride capsule) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

Description for Deconex Capsule

Drug Facts

Active Ingredients (in each capsule)

Guaifenesin 390 mg
Phenylephrine HCl 10 mg

Uses for Deconex Capsule

Purpose

  • Expectorant
  • Nasal Decongestant

Uses

Temporarily relieves these symptoms due to the common cold, hay fever (allergic rhinitis) or other upper respiratory allergies:

  • helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes and make coughs more productive
  • nasal congestion
  • reduces swelling of nasal passages

Dosage for Deconex Capsule

Directions

Do not exceed recommended dosage.

Adults and children 12 years of age and over: 1 capsule every 4 hours, not to exceed 6 capsules in 24 hours.
Children under 12 years of age: Consult a physician.

HOW SUPPLIED

Other Information

Store at controlled room temperature between 15°-30°C (59°-86°F).

Supplied in a tight, light-resistant container with a child-resistant cap.

NDC 50991-582-60

Deconex Capsules are blue-orange capsules imprinted "Deconex" in black ink.

Inactive Ingredients

Croscarmellose Sodium, Dicalcium Phosphate Dihydrate, FD&C Blue #1, FD&C Yellow #6, Gelatin, Magnesium Stearate, Maltodextrin, Povidone, Silicon Dioxide, Stearic Acid, and Titanium Dioxide.

Questions? Comments? Call 1-800-882-1041

Manufactured for: Poly Pharmaceuticals, Quitman, MS 39355, 1 (800) 882-1041. Revised: Nov 2011

Side Effects for Deconex Capsule

No information provided. Please see the WARNINGS AND PRECAUTIONS sections

Drug Interactions for Deconex Capsule

No information provided.

Warnings for Deconex Capsule

Included as part of the PRECAUTIONS section.

Precautions for Deconex Capsule

Do not exceed recommended dosage.

Do not use this product

Ask a doctor before use if you have

  • a cough that lasts or is chronic such as occurs with smoking, asthma, chronic bronchitis, or
    emphysema
  • a cough that occurs with too much phlegm (mucus)
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • trouble urinating due to an enlarged prostate gland

Stop use and ask a doctor if

  • nervousness, dizziness, or sleeplessness occur
  • cough or nasal congestion persists for more than 1 week, tends to recur, or is accompanied by a fever, rash, or persistent headache.
  • A persistent cough may be a sign of a serious condition.
    new symptoms occur

If pregnant or breast feeding, ask a health professional before use.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control
Center right away.

Overdose Information for Deconex Capsule

No information provided.

Contraindications for Deconex Capsule

No information provided.

Clinical Pharmacology for Deconex Capsule

No information provided.

Patient Information for Deconex Capsule

Do not exceed recommended dosage.

Do not use this product

  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use if you have

  • a cough that lasts or is chronic such as occurs with smoking, asthma, chronic bronchitis, or
    emphysema
  • a cough that occurs with too much phlegm (mucus)
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • trouble urinating due to an enlarged prostate gland

Stop use and ask a doctor if

  • nervousness, dizziness, or sleeplessness occur
  • cough or nasal congestion persists for more than 1 week, tends to recur, or is accompanied by a fever, rash, or persistent headache.
  • A persistent cough may be a sign of a serious condition.
    new symptoms occur

If pregnant or breast feeding, ask a health professional before use.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control
Center right away.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.