Flunisolide Intranasal

Flunisolide Intranasal is a prescription medication used for the treatment of Seasonal Allergic Rhinitis.

• Flunisolide Intranasal is available under the following different brand names: Nasalide

Common side effects of Flunisolide Intranasal include:

• burning or stinging in the nose
• stuffy nose
• sneezing
• minor nosebleed
• changes in the sense of smell or taste
• watery eyes
• irritation in the nose
• sore throat
• nausea
• vomiting
• headache

Serious side effects of Flunisolide Intranasal include:

• hives
• difficulty breathing
• swelling of the face, lips, tongue, or throat
• severe or ongoing nosebleeds
• itching, irritation, sores, or white patches in the nose, mouth, or throat
• crusting around the nostrils
• any wound that will not heal
• fever
• chills
• weakness
• flu symptoms

Rare side effects of Flunisolide Intranasal include:

• none 

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors;
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out.

This is not a complete list of side effects and other serious side effects or health problems that may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

Adult and pediatric dosage

Nasal spray

• 25 mcg/actuation
• 29 mcg/actuation

Seasonal Allergic Rhinitis

Adult dosage

• 2 sprays each nostril two times a day; may increase to three or four times a day

Pediatric dosage

• Less than 6 years: Safety and efficacy not established.
• 6-14 years: 1 spray each nostril three times a day, or 2 sprays each nostril twice a day

Administration

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

• Flunisolide Intranasal has no noted severe interactions with any other drugs.
• Flunisolide Intranasal has no noted serious interactions with any other drugs.
• Flunisolide Intranasal has no noted moderate interactions with any other drugs.
• Flunisolide Intranasal has no noted minor interactions with any other drugs.

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your healthcare professional or doctor for additional medical advice, or if you have health questions, concerns.

Contraindications

• Hypersensitivity
• Do not use with untreated local infection involving the nasal mucosa
• Recent nasal surgery/injury

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Flunisolide Intranasal?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Flunisolide Intranasal?”

Cautions

• Replacement of systemic corticosteroids with topical administration can be accompanied by signs of adrenal insufficiency: some patients may experience withdrawal symptoms.
• Intranasal corticosteroids may cause a reduction in growth velocity when administered to pediatric patients with rare reports of nasal septal perforation
• Temporary or permanent loss of sense of smell or taste reported.
• Because of the inhibitory effect of corticosteroids on wound healing, a nasal corticosteroid should be used with caution in patients who have experienced recent nasal septal ulcers, recurrent epistaxis, nasal surgery or trauma, until healing has occurred.
• Systemic corticoid effects typical of Cushing's syndrome are minimal with recommended doses of topical steroids, this potential increases with excessive doses.
• Corticosteroids are known to cause immunosuppression resulting in increased susceptibility to infection.

Pregnancy and Lactation

• There are no studies in pregnant women to inform a drug-associated risk for birth defects or miscarriage; there are clinical considerations with use in pregnant women to inform a drug-associated risk; in animal reproduction studies, flunisolide administered to pregnant rats and rabbits during organogenesis produced fetal structural abnormalities; dose in rats and rabbits was approximately 3 and 1 times maximum recommended human daily dose, respectively.
• Lactation
  • There is no information on the presence of flunisolide in human milk, or effects on the breastfed child, or on milk production; because other corticosteroids are excreted in human milk, exercise caution when administering therapy to nursing women.
  • The developmental and health benefits of breastfeeding should be considered along with mother’s clinical need and any potential adverse effects on breastfed infant from therapy or from underlying maternal conditions.