Ulspira

What Is Ulspira?

Ulspira (nitric oxide for inhalation) is a vasodilator indicated to improve oxygenation and reduce the need for extracorporeal membrane oxygenation in term and near-term (greater than 34 weeks’ gestation) neonates with hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension in conjunction with ventilatory support and other appropriate agents.

What Are Side Effects of Ulspira?

Side effects of Ulspira include:

• low blood pressure (hypotension),
• low blood oxygen (hypoxemia), and
• worsening heart failure.

Seek medical care or call 911 at once if you have the following serious side effects:

• Serious eye symptoms such as sudden vision loss, blurred vision,tunnel vision,eye painor swelling, or seeing halos around lights;
• Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheadedness, or passing out;
• Severe headache,confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Ulspira

The recommended dose of Ulspira is 20 ppm, maintained for up to 14 days or until the underlying oxygen desaturation has resolved.

Ulspira In Children

The safety and efficacy of Ulspira for inhalation has been demonstrated in term and near-term neonates with hypoxic respiratory failure associated with evidence of pulmonary hypertension.

No information about its effectiveness in other age populations is available.

What Drugs, Substances, or Supplements Interact with Ulspira?

Ulspira may interact with other medicines such as:

• nitric oxide donor compounds such as prilocaine, sodium nitroprusside, and nitroglycerine.

Tell your doctor all medications and supplements you use.

Ulspira During Pregnancy and Breastfeeding

Ulspira is not intended for use in adults so it is unlikely to be used during pregnancy or while breastfeeding.

Additional Information

Our Ulspira (nitric oxide for inhalation) Gas Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.